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Large-scale longitudinal molecular profiling is now firmly established in biomedical research, prompted by the need to uncover coordinated biomarker trajectories reflecting the dynamics of underlying biological mechanisms and characterise…

统计方法学 · 统计学 2026-03-24 Salima Jaoua , Daniel Temko , Hélène Ruffieux

Boolean matrix factorisation aims to decompose a binary data matrix into an approximate Boolean product of two low rank, binary matrices: one containing meaningful patterns, the other quantifying how the observations can be expressed as a…

机器学习 · 统计学 2017-02-28 Tammo Rukat , Chris C. Holmes , Michalis K. Titsias , Christopher Yau

Implementing Bayesian variable selection for linear Gaussian regression models for analysing high dimensional data sets is of current interest in many fields. In order to make such analysis operational, we propose a new sampling algorithm…

统计计算 · 统计学 2010-02-16 Leonardo Bottolo , Sylvia Richardson

Identifying differentially expressed genes from RNA sequencing data remains a challenging task because of the considerable uncertainties in parameter estimation and the small sample sizes in typical applications. Here we introduce Bayesian…

应用统计 · 统计学 2014-11-11 Matthias Katzfuss , Andreas Neudecker , Simon Anders , Julien Gagneur

Although Bayesian density estimation using discrete mixtures has good performance in modest dimensions, there is a lack of statistical and computational scalability to high-dimensional multivariate cases. To combat the curse of…

统计方法学 · 统计学 2014-10-29 Ye Wang , Antonio Canale , David Dunson

Statistical uncertainties are rarely incorporated in machine learning algorithms, especially for anomaly detection. Here we present the Bayesian Anomaly Detection And Classification (BADAC) formalism, which provides a unified statistical…

机器学习 · 统计学 2019-02-26 Ethan Roberts , Bruce A. Bassett , Michelle Lochner

This paper presents an efficient Bayesian framework for solving nonlinear, high-dimensional model calibration problems. It is based on a Variational Bayesian formulation that aims at approximating the exact posterior by means of solving an…

应用统计 · 统计学 2015-11-02 Isabell M. Franck , P. S. Koutsourelakis

Low-dimensional embeddings for data from disparate sources play critical roles in multi-modal machine learning, multimedia information retrieval, and bioinformatics. In this paper, we propose a supervised dimensionality reduction method…

机器学习 · 计算机科学 2021-01-15 Yanjun Li , Bihan Wen , Hao Cheng , Yoram Bresler

In tissue characterization and cancer diagnostics, multimodal imaging has emerged as a powerful technique. Thanks to computational advances, large datasets can be exploited to discover patterns in pathologies and improve diagnosis. However,…

计算机视觉与模式识别 · 计算机科学 2023-03-21 Eva Breznik , Elisabeth Wetzer , Joakim Lindblad , Nataša Sladoje

Bayesian mixture models are widely used for clustering of high-dimensional data with appropriate uncertainty quantification. However, as the dimension of the observations increases, posterior inference often tends to favor too many or too…

统计方法学 · 统计学 2022-11-22 Noirrit Kiran Chandra , Antonio Canale , David B. Dunson

This paper proposes a new method for solving Bayesian decision problems. The method consists of representing a Bayesian decision problem as a valuation-based system and applying a fusion algorithm for solving it. The fusion algorithm is a…

人工智能 · 计算机科学 2013-03-26 Prakash P. Shenoy

Boolean tensor decomposition approximates data of multi-way binary relationships as product of interpretable low-rank binary factors, following the rules of Boolean algebra. Here, we present its first probabilistic treatment. We facilitate…

机器学习 · 统计学 2018-05-15 Tammo Rukat , Chris C. Holmes , Christopher Yau

We introduce a new dataset, MELINDA, for Multimodal biomEdicaL experImeNt methoD clAssification. The dataset is collected in a fully automated distant supervision manner, where the labels are obtained from an existing curated database, and…

计算与语言 · 计算机科学 2020-12-18 Te-Lin Wu , Shikhar Singh , Sayan Paul , Gully Burns , Nanyun Peng

Deep learning has revolutionized the early detection of breast cancer, resulting in a significant decrease in mortality rates. However, difficulties in obtaining annotations and huge variations in distribution between training sets and real…

计算机视觉与模式识别 · 计算机科学 2024-09-02 Yuxiang Yang , Xinyi Zeng , Pinxian Zeng , Binyu Yan , Xi Wu , Jiliu Zhou , Yan Wang

Important objectives in cancer research are the prediction of a patient's risk based on molecular measurements such as gene expression data and the identification of new prognostic biomarkers (e.g. genes). In clinical practice, this is…

应用统计 · 统计学 2020-04-17 Katrin Madjar , Manuela Zucknick , Katja Ickstadt , Jörg Rahnenführer

Bayesian optimization is an effective methodology for the global optimization of functions with expensive evaluations. It relies on querying a distribution over functions defined by a relatively cheap surrogate model. An accurate model for…

Clustering algorithms have wide applications and play an important role in data analysis fields including time series data analysis. However, in time series analysis, most of the algorithms used signal shape features or the initial value of…

机器学习 · 统计学 2020-04-30 Daisuke Kaji , Kazuho Watanabe , Masahiro Kobayashi

We present Bayesian Diffusion Models (BDM), a prediction algorithm that performs effective Bayesian inference by tightly coupling the top-down (prior) information with the bottom-up (data-driven) procedure via joint diffusion processes. We…

计算机视觉与模式识别 · 计算机科学 2024-04-23 Haiyang Xu , Yu Lei , Zeyuan Chen , Xiang Zhang , Yue Zhao , Yilin Wang , Zhuowen Tu

Data augmentation is a crucial regularization technique for deep neural networks, particularly in medical image classification. Mainstream data augmentation (DA) methods are usually applied at the image level. Due to the specificity and…

计算机视觉与模式识别 · 计算机科学 2024-06-28 Yaoyao Zhu , Xiuding Cai , Xueyao Wang , Xiaoqing Chen , Yu Yao , Zhongliang Fu

We introduce Interactive Bayesian Distributional Robustness (IBDR), a novel Bayesian inference framework that allows modeling the interactions between particles, thereby enhancing ensemble quality through increased particle diversity. IBDR…

机器学习 · 计算机科学 2025-06-10 Ngoc-Quan Pham , Tuan Truong , Quyen Tran , Tan Nguyen , Dinh Phung , Trung Le