相关论文: scMEDAL for the interpretable analysis of single-c…

We propose a masked self-supervised learning framework, called BRepMAE, for automatically extracting a valuable representation of the input computer-aided design (CAD) model to recognize its machining features. Representation learning is…

Single-cell RNA sequencing (scRNA-seq) technology provides high-throughput gene expression data to study the cellular heterogeneity and dynamics of complex organisms. Graph neural networks (GNNs) have been widely used for automatic cell…

The rise of single-cell sequencing technologies has revolutionized the exploration of drug resistance, revealing the crucial role of cellular heterogeneity in advancing precision medicine. By building computational models from existing…

Existing semi-supervised medical segmentation co-learning frameworks have realized that model performance can be diminished by the biases in model recognition caused by low-quality pseudo-labels. Due to the averaging nature of their…

Spatial transcriptomics (ST) provides spatially resolved measurements of gene expression, enabling characterization of the molecular landscape of human tissue beyond histological assessment as well as localized readouts that can be aligned…

Single-cell RNA sequencing has transformed biology by enabling the measurement of gene expression at cellular resolution, providing information for cell types, states, and disease contexts. Recently, single-cell foundation models have…

Advances in deep learning (DL) have resulted in impressive accuracy in some medical image classification tasks, but often deep models lack interpretability. The ability of these models to explain their decisions is important for fostering…

To achieve high-levels of autonomy, modern robots require the ability to detect and recover from anomalies and failures with minimal human supervision. Multi-modal sensor signals could provide more information for such anomaly detection…

Learning from large heterogeneous graphs presents significant challenges due to the scale of networks, heterogeneity in node and edge types, variations in nodal features, and complex local neighborhood structures. This paper advocates for…

To enhance the performance of affective models and reduce the cost of acquiring physiological signals for real-world applications, we adopt multimodal deep learning approach to construct affective models from multiple physiological signals.…

Stochastic differential equations (SDEs) provide a natural framework for modelling intrinsic stochasticity inherent in many continuous-time physical processes. When such processes are observed in multiple individuals or experimental units,…

Large-scale multimodal contrastive learning has recently achieved impressive success in learning rich and transferable representations, yet it remains fundamentally limited by the uniform treatment of feature dimensions and the neglect of…

Graph Neural Networks (GNNs) have shown promise in learning dynamic functional connectivity for distinguishing phenotypes from human brain networks. However, obtaining extensive labeled clinical data for training is often…

Automated anomaly detection is essential for managing information and communications technology (ICT) systems to maintain reliable services with minimum burden on operators. For detecting varying and continually emerging anomalies as…

Sparse autoencoders (SAEs) emerged as a promising tool for mechanistic interpretability of transformer-based foundation models. Very recently, SAEs were also adopted for the visual domain, enabling the discovery of visual concepts and their…

The single-cell RNA sequencing (scRNA-seq) technology enables researchers to study complex biological systems and diseases with high resolution. The central challenge is synthesizing enough scRNA-seq samples; insufficient samples can impede…

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

As AI models achieve remarkable capabilities across diverse domains, understanding what representations they learn and how they encode concepts has become increasingly important for both scientific progress and trustworthy deployment.…

Automatic segmentation of diverse heterogeneous brain lesions using multi-modal MRI is a challenging problem in clinical neuroimaging, mainly because of the lack of generalizability and high prediction variance of pathology-specific deep…

Deep learning approaches achieve state-of-the-art performance for classifying radiology images, but rely on large labelled datasets that require resource-intensive annotation by specialists. Both semi-supervised learning and active learning…