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Adaptive experiments improve efficiency by adjusting treatment assignments based on past outcomes, but this adaptivity breaks the i.i.d.\ assumptions that underpin classical asymptotics. At the same time, many questions of interest are…

机器学习 · 统计学 2026-05-05 Houssam Zenati , Bariscan Bozkurt , Arthur Gretton

In application domains such as healthcare, we want accurate predictive models that are also causally interpretable. In pursuit of such models, we propose a causal regularizer to steer predictive models towards causally-interpretable…

机器学习 · 计算机科学 2017-02-24 Mohammad Taha Bahadori , Krzysztof Chalupka , Edward Choi , Robert Chen , Walter F. Stewart , Jimeng Sun

Estimating individualized treatment rules (ITRs) is crucial for tailoring interventions in precision medicine. Typical ITR estimation methods rely on conditional average treatment effects (CATEs) to guide treatment assignments. However,…

统计方法学 · 统计学 2025-10-20 Peng Wu , Qing Jiang , Shanshan Luo , Zhi Geng

Predicting the effects of chemical and genetic perturbations on quantitative cell states is a central challenge in computational biology, molecular medicine and drug discovery. Recent work has leveraged large-scale single-cell data and…

机器学习 · 计算机科学 2026-03-16 Michael Scholkemper , Sach Mukherjee

Nonlinear causal discovery from observational data imposes strict identifiability assumptions on the formulation of structural equations utilized in the data generating process. The evaluation of structure learning methods under assumption…

机器学习 · 统计学 2024-12-17 Georg Velev , Stefan Lessmann

Clinical language processing has received a lot of attention in recent years, resulting in new models or methods for disease phenotyping, mortality prediction, and other tasks. Unfortunately, many of these approaches are tested under…

计算与语言 · 计算机科学 2022-09-30 Travis R. Goodwin , Dina Demner-Fushman

Causal concept effect estimation is gaining increasing interest in the field of interpretable machine learning. This general approach explains the behaviors of machine learning models by estimating the causal effect of human-understandable…

机器学习 · 计算机科学 2024-11-15 Jifan Gao , Guanhua Chen

To gain deeper insights into a complex sensor system through the lens of causality, we present common and individual causal mechanism estimation (CICME), a novel three-step approach to inferring causal mechanisms from heterogeneous data…

机器学习 · 计算机科学 2025-08-21 Jingyi Yu , Tim Pychynski , Marco F. Huber

Automatic chest X-ray report generation is an important area of research aimed at improving diagnostic accuracy and helping doctors make faster decisions. Current AI models are good at finding correlations (or patterns) in medical images.…

机器学习 · 计算机科学 2025-12-16 Satyam Kumar

Causal reasoning and discovery, two fundamental tasks of causal analysis, often face challenges in applications due to the complexity, noisiness, and high-dimensionality of real-world data. Despite recent progress in identifying latent…

机器学习 · 计算机科学 2025-11-18 Dingling Yao , Shimeng Huang , Riccardo Cadei , Kun Zhang , Francesco Locatello

Standard approaches to causal inference, such as Outcome Regression and Inverse Probability Weighted Regression Adjustment (IPWRA), are typically derived through the lens of missing data imputation and identification theory. In this work,…

机器学习 · 统计学 2025-12-23 Ashley Zhang

Heterogeneous treatment effect estimation in high-stakes applications demands models that simultaneously optimize precision, interpretability, and calibration. Many existing tree-based causal inference techniques, however, exhibit high…

机器学习 · 计算机科学 2025-04-21 Yichen Liu

The rapid digitization of real-world data presents an unprecedented opportunity to optimize healthcare delivery and accelerate biomedical discovery. However, these data are often found in unstructured forms such as clinical notes in…

Estimating conditional average treatment effects (CATEs) from observational data is relevant in many fields such as personalized medicine. However, in practice, the treatment assignment is usually confounded by unobserved variables and thus…

统计方法学 · 统计学 2023-01-24 Dennis Frauen , Stefan Feuerriegel

Medical imaging diagnosis increasingly relies on Machine Learning (ML) models. This is a task that is often hampered by severely imbalanced datasets, where positive cases can be quite rare. Their use is further compromised by their limited…

With an increasing focus on precision medicine in medical research, numerous studies have been conducted in recent years to clarify the relationship between treatment effects and patient characteristics. The treatment effects for patients…

统计方法学 · 统计学 2023-09-22 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

Estimating how a treatment affects units individually, known as heterogeneous treatment effect (HTE) estimation, is an essential part of decision-making and policy implementation. The accumulation of large amounts of data in many domains,…

机器学习 · 计算机科学 2022-06-28 Christopher Tran , Elena Zheleva

The Causal Roadmap outlines a systematic approach to asking and answering questions of cause-and-effect: define the quantity of interest, evaluate needed assumptions, conduct statistical estimation, and carefully interpret results. To…

统计方法学 · 统计学 2024-05-30 Nerissa Nance , Maya L. Petersen , Mark van der Laan , Laura B. Balzer

Concept Bottleneck Models (CBMs) are a prominent framework for interpretable AI that map learned visual features to a set of meaningful concepts for task-specific downstream predictions. Their sequential structure enhances transparency by…

Causal learning is the key to obtaining stable predictions and answering \textit{what if} problems in decision-makings. In causal learning, it is central to seek methods to estimate the average treatment effect (ATE) from observational…

机器学习 · 统计学 2022-12-07 Yiyan Huang , Cheuk Hang Leung , Qi Wu , Xing Yan