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Magnetic Resonance Imaging (MRI) provides detailed structural information, while functional MRI (fMRI) captures temporal brain activity. In this work, we present a multimodal deep learning framework that integrates MRI and fMRI for…

计算机视觉与模式识别 · 计算机科学 2026-03-17 Anima Kujur , Zahra Monfared

We propose a novel framework for integrating fragmented multi-modal data in Alzheimer's disease (AD) research using large language models (LLMs) and knowledge graphs. While traditional multimodal analysis requires matched patient IDs across…

机器学习 · 计算机科学 2025-08-19 Kanan Kiguchi , Yunhao Tu , Katsuhiro Ajito , Fady Alnajjar , Kazuyuki Murase

Deep learning has shown outstanding performance in identifying intricate structures in complex high-dimensional data, especially in the domain of computer vision. The application of deep learning to early detection and automated…

图像与视频处理 · 电气工程与系统科学 2019-08-22 Taeho Jo , Kwangsik Nho , Andrew J. Saykin

We propose a Bayesian latent variable model to estimate covariate-assisted dependence structures across multiple modalities of multivariate data that may be observed asynchronously. This setting commonly arises in longitudinal biomedical…

统计方法学 · 统计学 2026-05-27 Kun Qian , Hyung G. Park

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

计算机视觉与模式识别 · 计算机科学 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

An ideal embodied agent should possess lifelong learning capabilities to handle long-horizon and complex tasks, enabling continuous operation in general environments. This not only requires the agent to accurately accomplish given tasks but…

人工智能 · 计算机科学 2026-03-24 Sen Wang , Bangwei Liu , Zhenkun Gao , Lizhuang Ma , Xuhong Wang , Yuan Xie , Xin Tan

Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel…

机器学习 · 计算机科学 2022-09-27 Michal Golovanevsky , Carsten Eickhoff , Ritambhara Singh

Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

人工智能 · 计算机科学 2025-12-01 Niccolo Marini , Zhaohui Liang , Sivaramakrishnan Rajaraman , Zhiyun Xue , Sameer Antani

We present a practical health-theme machine learning (ML) application concerning `AI for social good' domain for `Producing Good Outcomes' track. In particular, the solution is concerning the problem of a potential elderly adult dementia…

神经元与认知 · 定量生物学 2019-11-28 Tomasz M. Rutkowski , Masato S. Abe , Marcin Koculak , Mihoko Otake-Matsuura

Deep learning has been successful in predicting neurodegenerative disorders, such as Alzheimer's disease, from magnetic resonance imaging (MRI). Combining multiple imaging modalities, such as T1-weighted (T1) and diffusion-weighted imaging…

The variational autoencoder (VAE) is a popular deep latent variable model used to analyse high-dimensional datasets by learning a low-dimensional latent representation of the data. It simultaneously learns a generative model and an…

机器学习 · 计算机科学 2023-11-21 Mine Öğretir , Siddharth Ramchandran , Dimitrios Papatheodorou , Harri Lähdesmäki

This study investigates the potential of multimodal data integration, which combines electroencephalogram (EEG) data with sociodemographic characteristics like age, sex, education, and intelligence quotient (IQ), to diagnose mental diseases…

Modern data analytics take advantage of ensemble learning and transfer learning approaches to tackle some of the most relevant issues in data analysis, such as lack of labeled data to use to train the analysis models, sparsity of the…

In this paper, an innovative multi-modal deep learning model is proposed to deeply integrate heterogeneous information from medical images and clinical reports. First, for medical images, convolutional neural networks were used to extract…

机器学习 · 计算机科学 2024-05-29 Ziyan Yao , Fei Lin , Sheng Chai , Weijie He , Lu Dai , Xinghui Fei

Deep learning systems often struggle with processing long sequences, where computational complexity can become a bottleneck. Current methods for automated dementia detection using speech frequently rely on static, time-agnostic features or…

声音 · 计算机科学 2025-10-02 Chukwuemeka Ugwu , Oluwafemi Oyeleke

Deep learning has revolutionized biomedical research by providing sophisticated methods to handle complex, high-dimensional data. Multimodal deep learning (MDL) further enhances this capability by integrating diverse data types such as…

The ensemble empirical mode decomposition (EEMD) and its complete variant (CEEMDAN) are adaptive, noise-assisted data analysis methods that improve on the ordinary empirical mode decomposition (EMD). All these methods decompose possibly…

统计计算 · 统计学 2017-07-04 P. J. J. Luukko , J. Helske , E. Räsänen

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

机器学习 · 计算机科学 2025-11-07 Anzhuo Xie , Wei-Chen Chang

Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. Despite the many advantages of joint modeling, the standard forms suffer from limitations that arise…

机器学习 · 统计学 2018-07-10 Bryan Lim , Mihaela van der Schaar

The advent of Large Multimodal Models (LMMs) offers a promising technology to tackle the limitations of modular design in autonomous driving, which often falters in open-world scenarios requiring sustained environmental understanding and…

机器人学 · 计算机科学 2026-01-21 Long Zhang , Yuchen Xia , Bingqing Wei , Zhen Liu , Shiwen Mao , Zhu Han , Mohsen Guizani