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相关论文: MEG: Medical Knowledge-Augmented Large Language Mo…

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Large Language Models (LLMs) excel at language understanding but remain limited in knowledge-intensive domains due to hallucinations, outdated information, and limited explainability. Text-based retrieval-augmented generation (RAG) helps…

计算与语言 · 计算机科学 2026-02-09 Larissa Pusch , Alexandre Courtiol , Tim Conrad

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

计算与语言 · 计算机科学 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman

The ability of knowledge graphs to represent complex relationships at scale has led to their adoption for various needs including knowledge representation, question-answering, and recommendation systems. Knowledge graphs are often…

计算与语言 · 计算机科学 2023-05-18 Jason Youn , Ilias Tagkopoulos

Clinical diagnosis is time-consuming, requiring intensive interactions between patients and medical professionals. While large language models (LLMs) could ease the pre-diagnostic workload, their limited domain knowledge hinders effective…

计算与语言 · 计算机科学 2026-03-03 Liwen Sun , Xiang Yu , Ming Tan , Zhuohao Chen , Anqi Cheng , Ashutosh Joshi , Chenyan Xiong

Integrating large language models (LLMs) with knowledge graphs derived from domain-specific data represents an important advancement towards more powerful and factual reasoning. As these models grow more capable, it is crucial to enable…

人工智能 · 计算机科学 2024-04-19 Stefan Dernbach , Khushbu Agarwal , Alejandro Zuniga , Michael Henry , Sutanay Choudhury

Large Language Models (LLMs) are often criticized for lacking true "understanding" and the ability to "reason" with their knowledge, being seen merely as autocomplete systems. We believe that this assessment might be missing a nuanced…

人工智能 · 计算机科学 2024-06-18 Venkat Venkatasubramanian

Large language models (LLMs) have demonstrated impressive generative capabilities with the potential to innovate in medicine. However, the application of LLMs in real clinical settings remains challenging due to the lack of factual…

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

人工智能 · 计算机科学 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Large Language Models (LLMs) demonstrate remarkable capabilities, yet struggle with hallucination and outdated knowledge when tasked with complex knowledge reasoning, resulting in factually incorrect outputs. Previous studies have attempted…

计算与语言 · 计算机科学 2025-01-07 Derong Xu , Xinhang Li , Ziheng Zhang , Zhenxi Lin , Zhihong Zhu , Zhi Zheng , Xian Wu , Xiangyu Zhao , Tong Xu , Enhong Chen

Large language models (LLMs) acquire knowledge across diverse domains such as science, history, and geography encountered during generative pre-training. However, due to their stochasticity, it is difficult to predict what LLMs have…

计算与语言 · 计算机科学 2026-01-27 Kartik Sharma , Yiqiao Jin , Rakshit Trivedi , Srijan Kumar

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

定量方法 · 定量生物学 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Knowledge-intensive tasks pose a significant challenge for Machine Learning (ML) techniques. Commonly adopted methods, such as Large Language Models (LLMs), often exhibit limitations when applied to such tasks. Nevertheless, there have been…

机器学习 · 计算机科学 2024-05-20 Albert Sawczyn , Jakub Binkowski , Piotr Bielak , Tomasz Kajdanowicz

Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external…

计算与语言 · 计算机科学 2025-02-20 Yucheng Shi , Tianze Yang , Canyu Chen , Quanzheng Li , Tianming Liu , Xiang Li , Ninghao Liu

In this paper, we present a novel diagnostic framework that integrates Knowledge Graphs (KGs) and Large Language Models (LLMs) to support system diagnostics in high-reliability systems such as nuclear power plants. Traditional diagnostic…

人工智能 · 计算机科学 2025-09-01 Saman Marandi , Yu-Shu Hu , Mohammad Modarres

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

The problem of answering questions using knowledge from pre-trained language models (LMs) and knowledge graphs (KGs) presents two challenges: given a QA context (question and answer choice), methods need to (i) identify relevant knowledge…

计算与语言 · 计算机科学 2022-12-14 Michihiro Yasunaga , Hongyu Ren , Antoine Bosselut , Percy Liang , Jure Leskovec

Large language models (LLMs) have made significant progress in general-purpose natural language processing tasks. However, LLMs are still facing challenges when applied to domain-specific areas like telecommunications, which demands…

计算与语言 · 计算机科学 2025-05-22 Dun Yuan , Hao Zhou , Di Wu , Xue Liu , Hao Chen , Yan Xin , Jianzhong , Zhang

Recent advancements in Large Language Models (LLMs) have drawn increasing attention since the learned embeddings pretrained on large-scale datasets have shown powerful ability in various downstream applications. However, whether the learned…

计算与语言 · 计算机科学 2023-02-07 Jielin Qiu , William Han , Jiacheng Zhu , Mengdi Xu , Michael Rosenberg , Emerson Liu , Douglas Weber , Ding Zhao

Large language models (LLMs) are increasingly used in the mental health domain, yet it remains unclear how well they capture related biomedical knowledge and how reliably they apply it to clinically salient structured judgments. Here, we…