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In healthcare, applying deep learning models to electronic health records (EHRs) has drawn considerable attention. EHR data consist of a sequence of medical visits, i.e. a multivariate time series of diagnosis, medications, physical…

机器学习 · 计算机科学 2018-10-19 Jing Mei , Shiwan Zhao , Feng Jin , Eryu Xia , Haifeng Liu , Xiang Li

Medication recommendation systems have gained significant attention in healthcare as a means of providing tailored and effective drug combinations based on patients' clinical information. However, existing approaches often suffer from…

机器学习 · 计算机科学 2024-08-13 Zihao Zhao , Yi Jing , Fuli Feng , Jiancan Wu , Chongming Gao , Xiangnan He

The treatment effects of medications play a key role in guiding medical prescriptions. They are usually assessed with randomized controlled trials (RCTs), which are expensive. Recently, large-scale electronic health records (EHRs) have…

The problem of accelerating drug discovery relies heavily on automatic tools to optimize precursor molecules to afford them with better biochemical properties. Our work in this paper substantially extends prior state-of-the-art on…

化学物理 · 物理学 2019-10-22 Wengong Jin , Regina Barzilay , Tommi Jaakkola

Hierarchical text classification (HTC) is essential for various real applications. However, HTC models are challenging to develop because they often require processing a large volume of documents and labels with hierarchical taxonomy.…

计算与语言 · 计算机科学 2023-11-08 SangHun Im , Gibaeg Kim , Heung-Seon Oh , Seongung Jo , Donghwan Kim

Hierarchical text classification (HTC) is a special sub-task of multi-label classification (MLC) whose taxonomy is constructed as a tree and each sample is assigned with at least one path in the tree. Latest HTC models contain three…

计算与语言 · 计算机科学 2024-08-13 Zhijian Chen , Zhonghua Li , Jianxin Yang , Ye Qi

This work presents Homomorphic Encryption Intermediate Representation (HEIR), a unified approach to building homomorphic encryption (HE) compilers. HEIR aims to support all mainstream techniques in homomorphic encryption, integrate with all…

Next point-of-interest (POI) recommendation is a critical task in location-based social networks, yet remains challenging due to a high degree of variation and personalization exhibited in user movements. In this work, we explore the latent…

信息检索 · 计算机科学 2023-10-24 Jiayi Xie , Zhenzhong Chen

We propose a method to match anatomical locations between pairs of medical images in longitudinal comparisons. The matching is made possible by computing a descriptor of the query point in a source image based on a hierarchical sparse…

图像与视频处理 · 电气工程与系统科学 2023-09-26 Halid Ziya Yerebakan , Yoshihisa Shinagawa , Mahesh Ranganath , Simon Allen-Raffl , Gerardo Hermosillo Valadez

Medical coding translates free-text clinical documentation into standardized codes drawn from classification systems that contain tens of thousands of entries and are updated annually. It is central to billing, clinical research, and…

人工智能 · 计算机科学 2026-04-01 Joakim Edin , Andreas Motzfeldt , Simon Flachs , Lars Maaløe

How data is represented and operationalized is critical for building computational solutions that are both effective and efficient. A common approach is to represent data objects as binary vectors, denoted \textit{hash codes}, which require…

信息检索 · 计算机科学 2021-09-07 Casper Hansen

A pharmacological effect of a drug on cells, organs and systems refers to the specific biochemical interaction produced by a drug substance, which is called its mechanism of action. Drug repositioning (or drug repurposing) is a fundamental…

机器学习 · 计算机科学 2020-05-19 Dehua Chen , Amir Jalilifard , Adriano Veloso , Nivio Ziviani

Hierarchical text classification is a challenging subtask of multi-label classification due to its complex label hierarchy. Existing methods encode text and label hierarchy separately and mix their representations for classification, where…

计算与语言 · 计算机科学 2022-03-24 Zihan Wang , Peiyi Wang , Lianzhe Huang , Xin Sun , Houfeng Wang

Characterizing users' interests accurately plays a significant role in an effective recommender system. The sequential recommender system can learn powerful hidden representations of users from successive user-item interactions and dynamic…

社会与信息网络 · 计算机科学 2020-11-24 Lingxiao Zhang , Jiangpeng Yan , Yujiu Yang , Xiu Li

We are interested in building collaborative filtering models for recommendation systems where users interact with slates instead of individual items. These slates can be hierarchical in nature. The central idea of our approach is to learn…

信息检索 · 计算机科学 2020-10-15 Ehtsham Elahi , Ashok Chandrashekar

The growing demand for key healthcare resources such as clinical expertise and facilities has motivated the emergence of artificial intelligence (AI) based decision support systems. We address the problem of predicting clinical workups for…

机器学习 · 计算机科学 2020-07-24 Morteza Noshad , Ivana Jankovic , Jonathan H. Chen

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

人工智能 · 计算机科学 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

Retrosynthesis is essential for designing synthetic pathways for complex molecules and can be revolutionized by AI to automate and accelerate chemical synthesis planning for drug discovery and materials science. Here, we propose a…

化学物理 · 物理学 2024-12-02 Seongeun Yun , Won Bo Lee

Existing Masked Image Modeling methods apply fixed mask patterns to guide the self-supervised training. As those mask patterns resort to different criteria to depict image contents, sticking to a fixed pattern leads to a limited vision cues…

计算机视觉与模式识别 · 计算机科学 2025-04-15 Zhanzhou Feng , Shiliang Zhang

Objective: To transform heterogeneous clinical data from electronic health records into clinically meaningful constructed features using data driven method that rely, in part, on temporal relations among data. Materials and Methods: The…

机器学习 · 计算机科学 2017-06-22 Edward Choi , Andy Schuetz , Walter F. Stewart , Jimeng Sun