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Large-scale models pre-trained on large-scale datasets have profoundly advanced the development of deep learning. However, the state-of-the-art models for medical image segmentation are still small-scale, with their parameters only in the…

计算机视觉与模式识别 · 计算机科学 2023-04-14 Ziyan Huang , Haoyu Wang , Zhongying Deng , Jin Ye , Yanzhou Su , Hui Sun , Junjun He , Yun Gu , Lixu Gu , Shaoting Zhang , Yu Qiao

Instance segmentation in electron microscopy (EM) volumes is tough due to complex shapes and sparse annotations. Self-supervised learning helps but still struggles with intricate visual patterns in EM. To address this, we propose a…

计算机视觉与模式识别 · 计算机科学 2023-09-06 Yinda Chen , Wei Huang , Xiaoyu Liu , Shiyu Deng , Qi Chen , Zhiwei Xiong

Recent advances in self-supervised deep learning have improved our ability to quantify cellular morphological changes in high-throughput microscopy screens, a process known as morphological profiling. However, most current methods only…

机器学习 · 计算机科学 2026-05-18 Yemin Yu , Emre Hayir , Neil Tenenholtz , Lester Mackey , Ying Wei , David Alvarez-Melis , Ava P. Amini , Alex X. Lu

Analyzing microscopy images to extract biological object properties (e.g., their morphological organization, temporal dynamics, and population density) is fundamental to various biomedical research. Yet conducting this manually is costly…

计算机视觉与模式识别 · 计算机科学 2026-05-15 Xiaofei Hui , Haoxuan Qu , Hossein Rahmani , Shuohong Wang , Jeff W. Lichtman , Jun Liu

We propose a method to facilitate exploration and analysis of new large data sets. In particular, we give an unsupervised deep learning approach to learning a latent representation that captures semantic similarity in the data set. The core…

计算机视觉与模式识别 · 计算机科学 2020-12-23 Gary B Huang , Huei-Fang Yang , Shin-ya Takemura , Pat Rivlin , Stephen M Plaza

Images of the natural world, collected by a variety of cameras, from drones to individual phones, are increasingly abundant sources of biological information. There is an explosion of computational methods and tools, particularly computer…

Histopathological images of tumors contain abundant information about how tumors grow and how they interact with their micro-environment. Better understanding of tissue phenotypes in these images could reveal novel determinants of…

图像与视频处理 · 电气工程与系统科学 2021-04-14 Adalberto Claudio Quiros , Roderick Murray-Smith , Ke Yuan

Analyzing the morphology of cells in microscopy images can provide insights into the mechanism of compounds or the function of genes. Addressing this task requires methods that can not only extract biological information from the images,…

机器学习 · 计算机科学 2021-12-07 Siqi Wang , Manyuan Lu , Nikita Moshkov , Juan C. Caicedo , Bryan A. Plummer

Generative AI has recently propelled the decoding of images from brain activity. How do these approaches scale with the amount and type of neural recordings? Here, we systematically compare image decoding from four types of non-invasive…

图像与视频处理 · 电气工程与系统科学 2025-01-29 Hubert Banville , Yohann Benchetrit , Stéphane d'Ascoli , Jérémy Rapin , Jean-Rémi King

Computational models that predict cellular phenotypic responses to chemical and genetic perturbations can accelerate drug discovery by prioritizing therapeutic hypotheses and reducing costly wet-lab iteration. However, extracting…

计算机视觉与模式识别 · 计算机科学 2025-09-25 Pin-Jui Huang , Yu-Hsuan Liao , SooHeon Kim , NoSeong Park , JongBae Park , DongMyung Shin

We launch EVA, a vision-centric foundation model to explore the limits of visual representation at scale using only publicly accessible data. EVA is a vanilla ViT pre-trained to reconstruct the masked out image-text aligned vision features…

计算机视觉与模式识别 · 计算机科学 2022-12-06 Yuxin Fang , Wen Wang , Binhui Xie , Quan Sun , Ledell Wu , Xinggang Wang , Tiejun Huang , Xinlong Wang , Yue Cao

In recent years, deep learning has made brilliant achievements in Environmental Microorganism (EM) image classification. However, image classification of small EM datasets has still not obtained good research results. Therefore, researchers…

计算机视觉与模式识别 · 计算机科学 2022-02-04 Peng Zhao , Chen Li , Md Mamunur Rahaman , Hao Xu , Hechen Yang , Hongzan Sun , Tao Jiang , Marcin Grzegorzek

Understanding of human visual perception has historically inspired the design of computer vision architectures. As an example, perception occurs at different scales both spatially and temporally, suggesting that the extraction of salient…

计算机视觉与模式识别 · 计算机科学 2023-11-20 Girish Narayanswamy , Yujia Liu , Yuzhe Yang , Chengqian Ma , Xin Liu , Daniel McDuff , Shwetak Patel

Transformer-based models, capable of learning better global dependencies, have recently demonstrated exceptional representation learning capabilities in computer vision and medical image analysis. Transformer reformats the image into…

An image dataset of 10 different size molecules, where each molecule has 2,000 structural variants, is generated from the 2D cross-sectional projection of Molecular Dynamics trajectories. The purpose of this dataset is to provide a…

图像与视频处理 · 电气工程与系统科学 2019-11-19 Yan Zhang , Steve Farrell , Michael Crowley , Lee Makowski , Jack Deslippe

Combining experiments with artificial intelligence algorithms, we propose a new machine learning based approach to extract the cellular force distributions from the microscope images. The full process can be divided into three steps. First,…

We share our recent findings in an attempt to train a universal segmentation network for various cell types and imaging modalities. Our method was built on the generalized U-Net architecture, which allows the evaluation of each component…

计算机视觉与模式识别 · 计算机科学 2022-08-01 Tianqi Guo , Yin Wang , Luis Solorio , Jan P. Allebach

Feature foundation models - usually vision transformers - offer rich semantic descriptors of images, useful for downstream tasks such as (interactive) segmentation and object detection. For computational efficiency these descriptors are…

计算机视觉与模式识别 · 计算机科学 2025-09-01 Ronan Docherty , Antonis Vamvakeros , Samuel J. Cooper

As AI workloads increase in scope, generalization capability becomes challenging for small task-specific models and their demand for large amounts of labeled training samples increases. On the contrary, Foundation Models (FMs) are trained…

人工智能 · 计算机科学 2024-04-19 Aristeidis Tsaris , Philipe Ambrozio Dias , Abhishek Potnis , Junqi Yin , Feiyi Wang , Dalton Lunga

Spatial Transcriptomics (ST) technologies provide biologists with rich insights into single-cell biology by preserving spatial context of cells. Building foundational models for ST can significantly enhance the analysis of vast and complex…

基因组学 · 定量生物学 2025-07-24 Suyuan Zhao , Yizhen Luo , Ganbo Yang , Yan Zhong , Hao Zhou , Zaiqing Nie