相关论文: Quantum enhanced real-time sensing of protein-gold…

Absorption measurement is an exceptionally versatile tool for many applications in science and engineering. For absorption measurements using laser beams of light, the sensitivity is theoretically limited by the shot noise due to the…

Kinetic models are essential for describing how molecules interact in a variety of biochemical processes. The estimation of a model's kinetic parameters by experiment enables researchers to understand how pathogens, such as viruses,…

Absorption and gain processes are fundamental to any light-matter interaction and a precise measurement of these parameters is important for various scientific and technological applications. Quantum probes, specifically the squeezed states…

Absorption spectroscopy is a widely used technique that permits the detection and characterization of gas species at low concentrations. We propose a sensing strategy combining the advantages of frequency modulation spectroscopy with the…

We investigate the use of twin-mode quantum states of light with symmetric statistical features in their photon number for improving intensity-sensitive surface plasmon resonance (SPR) sensors. For this purpose, one of the modes is sent…

Among the known resources of quantum metrology, one of the most practical and efficient is squeezing. Squeezed states of atoms and light improve the sensing of the phase, magnetic field, polarization, mechanical displacement. They promise…

We present results from an instrument combining surface acoustic wave (SAW) propagation and surface plasmon resonance (SPR) measurements. The objective is to use two independent methods, the former based on adsorbed mass change measurements…

Label-free optical microscopy through absorption or scattering spectroscopy provides fundamental insights across biology and materials science, yet its sensitivity remains fundamentally limited by photon shot noise. While recent…

The measurement of parameters that describe kinetic processes is important in the study of molecular interactions. It enables a deeper understanding of the physical mechanisms underlying how different biological entities interact with each…

Stimulated Raman scattering (SRS) microscopy has emerged as a powerful technique for probing the spatiotemporal dynamics of molecular bonds with exceptional sensitivity, resolution, and speed. However, classically, its performance remains…

We investigate the sensitivity of gravitational acceleration estimation using squeezed probe states in a quantum metrology framework. In particular, we analyze how the squeezing phase, beyond its amplitude, affects the attainable precision.…

Quantum metrology enables estimation of optical phase shifts with precision beyond the shot-noise limit. One way to exceed this limit is to use squeezed states, where the quantum noise of one observable is reduced at the expense of…

Stimulated Raman scattering (SRS) microscopy is a powerful label-free imaging technique that probes the vibrational response of chemicals with high specificity and sensitivity. High-power, quantum-enhanced SRS microscopes have been recently…

Quantum entanglement, in the form of spin squeezing, is known to improve the sensitivity of atomic instruments to static or slowly-varying quantities. Sensing transient events presents a distinct challenge, requires different analysis…

Quantum enhanced sensing is a powerful technique in which nonclassical states are used to improve the sensitivity of a measurement. For enhanced mechanical displacement sensing, squeezed states of light have been shown to reduce the photon…

This thesis presents three studies in quantum-enhanced sensing and target detection. The first study explores covert target detection using optical or microwave probes, establishing quantum-mechanical limits on the error probabilities of…

Photonic sensors have many applications in a range of physical settings, from measuring mechanical pressure in manufacturing to detecting protein concentration in biomedical samples. A variety of sensing approaches exist, and plasmonic…

Stimulated Raman spectroscopy has become a powerful tool to study the spatiodynamics of molecular bonds with high sensitivity, resolution and speed. However, sensitivity and speed of state-of-the-art stimulated Raman spectroscopy are…

Recovering both amplitude and phase information from a system is a fundamental goal of optical imaging. At the same time, it is crucial to operate at low photon doses to avoid altering the sample, particularly in biological applications.…

Spin-squeezed states constitute a valuable entanglement resource capable of surpassing the standard quantum limit (SQL). However, spin-squeezed states only enable sub-SQL uncertainty within a narrow parametric window near some specific…