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Purpose: The presence of respiratory motion during radiation treatment leads to degradation of the expected dose distribution, both for target coverage and healthy-tissue sparing, particularly for techniques like pencil-beam scanning proton…

This article examines the critical role of fast Monte Carlo dose calculations in advancing proton therapy techniques, particularly in the context of increasing treatment customization and precision. As adaptive radiotherapy and other…

医学物理 · 物理学 2024-04-24 Jason Holmes , Hongying Feng , Lian Zhang , Michael Fix , Steve B. Jiang , Wei Liu

Monte Carlo (MC) simulation is considered the gold standard method for radiotherapy dose calculation. However, achieving high precision requires a large number of simulation histories, which is time consuming. The use of computer graphics…

计算机视觉与模式识别 · 计算机科学 2020-12-24 Ti Bai , Biling Wang , Dan Nguyen , Steve Jiang

Cone beam CT (CBCT) has been widely used for patient setup in image guided radiation therapy (IGRT). Radiation dose from CBCT scans has become a clinical concern. The purposes of this study are 1) to commission a GPU-based Monte Carlo (MC)…

The interplay between the beam delivery time structure and the patient motion makes 4D dose calculation (4DDC) important when treating moving tumors with intensity modulated proton therapy. 4DDC based on phase sorting of a 4DCT suffers from…

医学物理 · 物理学 2023-10-13 Ivar Bengtsson , Erik Engwall , Albin Fredriksson , Lars Glimelius

The diverse near-Earth radiation environment due to cosmic rays and solar radiation has direct impact on human civilization. In the present and upcoming era of increasing air transfer, it is important to have precise idea of radiation dose…

医学物理 · 物理学 2021-12-16 Abhijit Roy , Ritabrata Sarkar , Choonsik Lee

An essential component in proton radiotherapy is the algorithm to calculate the radiation dose to be delivered to the patient. The most common dose algorithms are fast but they are approximate analytical approaches. However their level of…

医学物理 · 物理学 2015-05-20 Pablo P Yepes , Dragan Mirkovic , Phillip J Taddei

Radiation dose is an important performance indicator of a dedicated breast CT (DBCT). In this paper, the method of putting thermoluminescent dosimeters (TLD) into a breast shaped PMMA phantom to study the dose distribution in breasts was…

医学物理 · 物理学 2013-05-14 Shen Shan-Wei , Wang Yan-Fang , Shu Hang , Tang Xiao , Wei Cun-Feng , Song Yu-Shou , Shi Rong-Jian , Wei Long

Cancer is a primary cause of morbidity and mortality worldwide. The radiotherapy plays a more and more important role in cancer treatment. In the radiotherapy, the dose distribution maps in patient need to be calculated and evaluated for…

医学物理 · 物理学 2019-10-18 Zhao Peng , Hongming Shan , Tianyu Liu , Xi Pei , Jieping Zhou , Ge Wang , X. George Xu

Cone-beam breast computed tomography (CT) provides true 3D breast images with isotropic resolution and high-contrast information, detecting calcifications as small as a few hundred microns and revealing subtle tissue differences. However,…

医学物理 · 物理学 2019-12-18 Wenxiang Cong , Hongming Shan , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang

PURPOSE: Permanent breast seed implant (PBSI) using 103Pd is emerging as an effective adjuvant radiation technique for early-stage breast cancer. However, clinical dose evaluations follow the water-based TG-43 approach with its considerable…

Computed Tomography (CT) measures the attenuation coefficient of an object and converts the value assigned to each voxel into a CT number. In radiation therapy, CT number, which is directly proportional to the linear attenuation…

医学物理 · 物理学 2015-03-13 Dong Joo Rhee , Sung-woo Kim , Young Min Moon , Jung Ki Kim , Dong Hyeok Jeong

Computer hardware costs are the limiting factor in producing highly accurate radiation dose calculations on convenient time scales. Because of this, large-scale, full Monte Carlo simulations and other resource intensive algorithms are often…

医学物理 · 物理学 2010-09-28 Roy W. Keyes , Christian Romano , Dorian Arnold , Shuang Luan

Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…

Monte Carlo (MC) simulation is commonly considered to be the most accurate dose calculation method in radiotherapy. However, its efficiency still requires improvement for many routine clinical applications. In this paper, we present our…

医学物理 · 物理学 2015-05-28 Xun Jia , Xuejun Gu , Yan Jiang Graves , Michael Folkerts , Steve B. Jiang

Purpose: To validate the accuracy of 4D Monte Carlo (4DMC) simulations to calculate dose deliveries to a deforming anatomy in the presence of realistic respiratory motion traces. A previously developed deformable lung phantom comprising an…

医学物理 · 物理学 2023-05-04 Sara Gholampourkashi , Joanna E. Cygler , Bernie Lavigne , Emily Heath

Improving effective treatment plans in carbon ion therapy, especially for targeting radioresistant tumors located in deep seated regions while sparing normal tissues, depends on a precise and computationally efficient dose calculation…

医学物理 · 物理学 2025-06-25 Fulya Halıcılar , Metin Arık

Computed tomography (CT) scans are a major source of medical radiation exposure worldwide. In countries like China, the frequency of CT scans has grown rapidly, particularly in routine physical examinations where chest CT scans are…

医学物理 · 物理学 2025-04-10 Zirui Ye , Bei Yao , Haoran Zheng , Li Tao , Ripeng Wang , Yankui Chang , Zhi Chen , Yingming Zhao , Wei Wei , Xie George Xu

In radiotherapy, a trade-off exists between computational workload/speed and dose calculation accuracy. Calculation methods like pencil-beam convolution can be much faster than Monte-Carlo methods, but less accurate. The dose difference,…

医学物理 · 物理学 2020-05-18 Yixun Xing , Ph. D. , You Zhang , Ph. D. , Dan Nguyen , Ph. D. , Mu-Han Lin , Ph. D. , Weiguo Lu , Ph. D. , Steve Jiang , Ph. D

The treatment of breast cancer using radiotherapy involves uncertainties regarding breast positioning. As the studies progress, more is known about the expected breast positioning errors, which are taken into account in the Planning Target…

计算几何 · 计算机科学 2025-03-28 Pierre Galmiche , Hyewon Seo , Yvan Pin , Philippe Meyer , Georges Noël , Michel de Mathelin
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