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Contact inhibition plays a crucial role in the motility of cells, the process of wound healing, and the formation of tumors. By mimicking the mechanical motion of calls crawling on a substrate using a pseudopod, we constructed a minimal…

软凝聚态物质 · 物理学 2016-11-28 Simon Kaspar Schnyder , Yuki Tanaka , John Jairo Molina , Ryoichi Yamamoto

Swarming or collective motion of living entities is one of the most common and spectacular manifestations of living systems having been extensively studied in recent years. A number of general principles have been established. The…

细胞行为 · 定量生物学 2014-06-06 Elod Mehes , Tamas Vicsek

There are rich emergent phase behaviors in non-equilibrium active systems. Flocking and clustering are two representative dynamic phases. The relationship between these two phases is still unclear. In the paper, we numerically investigate…

软凝聚态物质 · 物理学 2023-08-09 Lu Chen , Bokai Zhang , Z. C. Tu

Active fluids are intrinsically out-of-equilibrium systems due to the internal energy injection of the active constituents. We show here that a transition from a motion-less isotropic state towards a flowing polar one can be possibly driven…

软凝聚态物质 · 物理学 2021-05-12 M. G. Giordano , F. Bonelli , L. N. Carenza , G. Gonnella , G. Negro

We study in detail the active Ising model, a stochastic lattice gas where collective motion emerges from the spontaneous breaking of a discrete symmetry. On a 2d lattice, active particles undergo a diffusion biased in one of two possible…

统计力学 · 物理学 2015-10-12 A. P. Solon , J. Tailleur

We study the spontaneous motion, binary collisions, and collective dynamics of "polar disks", i.e. purpose-built particles which, when vibrated between two horizontal plates, move coherently along a direction strongly correlated to their…

软凝聚态物质 · 物理学 2016-01-19 Julien Deseigne , Sébastien Léonard , Olivier Dauchot , Hugues Chaté

We present a comprehensive study of Vicsek-style self-propelled particle models in two and three space dimensions. The onset of collective motion in such stochastic models with only local alignment interactions is studied in detail and…

统计力学 · 物理学 2009-11-13 Hugues Chaté , Francesco Ginelli , Guillaume Grégoire , Franck Raynaud

The collective behavior of active semiflexible filaments is studied with a model of tangentially driven self-propelled worm-like chains. The combination of excluded-volume interactions and self-propulsion leads to several distinct dynamic…

生物物理 · 物理学 2024-06-03 Ozer Duman , Rolf E. Isele-Holder , Jens Elgeti , Gerhard Gompper

We use computer simulations to study the microscopic dynamics of an athermal assembly of soft particles near the fluid-to-solid, jamming transition. Borrowing tools developed to study dynamic heterogeneity near glass transitions, we…

材料科学 · 物理学 2010-06-24 Claus Heussinger , Ludovic Berthier , Jean-Louis Barrat

In order to keep their cohesiveness during locomotion gregarious animals must make collective decisions. Many species boast complex societies with multiple levels of communities. A common case is when two dominant levels exist, one…

生物物理 · 物理学 2017-04-03 Bence Ferdinandy , Katalin Ozogány , Tamás Vicsek

We study the collective dynamics of elongated swimmers in a very thin fluid layer by devising long, filamentous, non-tumbling bacteria. The strong confinement induces weak nematic alignment upon collision, which, for large enough density of…

统计力学 · 物理学 2017-02-22 Daiki Nishiguchi , Ken H. Nagai , Hugues Chaté , Masaki Sano

When interacting motile units self-organize into flocks, they realize one of the most robust ordered state found in nature. However, after twenty five years of intense research, the very mechanism controlling the ordering dynamics of both…

软凝聚态物质 · 物理学 2021-10-04 Amélie Chardac , Ludwig A. Hoffmann , Yoann Poupart , Luca Giomi , Denis Bartolo

Multicellular collective migration is a ubiquitous strategy of cells to translocate spatially in diverse tissue environments to accomplish a wide variety of biological phenomena, viz. embryonic development, wound healing, and tumor…

细胞行为 · 定量生物学 2022-01-20 Ushasi Roy , Tyler Collins , Mohit K. Jolly , Parag Katira

Cell sorting, the segregation of cells with different properties into distinct domains, is a key phenomenon in biological processes such as embryogenesis. We use a phase-field model of a confluent cell layer to study the role of activity in…

生物物理 · 物理学 2024-03-05 James N. Graham , Guanming Zhang , Julia M. Yeomans

A combination of cellular contractility and active phase separation in cell-matrix composites is thought to be an enabler of spatiotemporal patterning in multicellular tissues across scales, from somitogenesis to cartilage condensation. To…

软凝聚态物质 · 物理学 2022-11-21 Sifan Yin , L Mahadevan

Experimental studies of cell motility in culture have shown that under adequate conditions these living organisms possess the ability to organize themselves into complex structures. Such structures may exhibit a synergy that greatly…

统计力学 · 物理学 2021-10-27 G. Nakamura , M. Badoual , E. Fabiani , C. Deroulers

Activity-mediated unjamming of a confluent glassy system is crucial for several biological processes, such as embryogenesis and cancer metastasis. During these processes, the cells progressively change their junction properties,…

软凝聚态物质 · 物理学 2025-05-13 Souvik Sadhukhan , Chandan Dasgupta , Saroj Kumar Nandi

How the cells break symmetry and organize their edge activity to move directionally is a fun- damental question in cell biology. Physical models of cell motility commonly rely on gradients of regulatory factors and/or feedback from the…

We study a two-dimensional crystal composed of active units governed by self-alignment. This mechanism induces a torque that aligns a particle's orientation with its velocity and leads to a phase transition from a disordered to a flocking…

软凝聚态物质 · 物理学 2025-06-17 Marco Musacchio , Alexander P. Antonov , Hartmut Löwen , Lorenzo Caprini

The investigation of collective behaviour in dense assemblies of self-propelled active particles has been motivated by a wide range of biological phenomena. Of particular interest are dynamical transitions of cellular and sub-cellular…

软凝聚态物质 · 物理学 2023-12-05 Yagyik Goswami , G. V. Shivashankar , Srikanth Sastry