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Gleason grading specified in ISUP 2014 is the clinical standard in staging prostate cancer and the most important part of the treatment decision. However, the grading is subjective and suffers from high intra and inter-user variability. To…

Prostate cancer is the most prevalent cancer among men in Western countries, with 1.1 million new diagnoses every year. The gold standard for the diagnosis of prostate cancer is a pathologists' evaluation of prostate tissue. To potentially…

图像与视频处理 · 电气工程与系统科学 2020-10-23 Hans Pinckaers , Wouter Bulten , Jeroen van der Laak , Geert Litjens

Digital pathology is not only one of the most promising fields of diagnostic medicine, but at the same time a hot topic for fundamental research. Digital pathology is not just the transfer of histopathological slides into digital…

Prostate cancer (PCa) was the most frequently diagnosed cancer among American men in 2023. The histological grading of biopsies is essential for diagnosis, and various deep learning-based solutions have been developed to assist with this…

图像与视频处理 · 电气工程与系统科学 2024-09-16 Ekaterina Redekop , Mara Pleasure , Zichen Wang , Anthony Sisk , Yang Zong , Kimberly Flores , William Speier , Corey W. Arnold

Prostate cancer is one of the most frequently diagnosed malignancies in men worldwide. However, precise prediction of biochemical recurrence (BCR) after radical prostatectomy remains challenging due to the multifocality of tumors…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Yesung Cho , Dongmyung Shin , Sujeong Hong , Jooyeon Lee , Seongmin Park , Geongyu Lee , Jongbae Park , Hong Koo Ha

Architecture, size, and shape of glands are most important patterns used by pathologists for assessment of cancer malignancy in prostate histopathological tissue slides. Varying structures of glands along with cumbersome manual observations…

图像与视频处理 · 电气工程与系统科学 2019-10-10 Malay Singh , Emarene Mationg Kalaw , Wang Jie , Mundher Al-Shabi , Chin Fong Wong , Danilo Medina Giron , Kian-Tai Chong , Maxine Tan , Zeng Zeng , Hwee Kuan Lee

Prostate cancer ranks among the leading health issues impacting men, with the Gleason scoring system serving as the primary method for diagnosis and prognosis. This system relies on expert pathologists to evaluate samples of prostate tissue…

图像与视频处理 · 电气工程与系统科学 2024-10-04 Amin Malekmohammadi , Ali Badiezadeh , Seyed Mostafa Mirhassani , Parisa Gifani , Majid Vafaeezadeh

Explainable AI (XAI) in medical histopathology is essential for enhancing the interpretability and clinical trustworthiness of deep learning models in cancer diagnosis. However, the black-box nature of these models often limits their…

图像与视频处理 · 电气工程与系统科学 2025-05-06 Raktim Kumar Mondol , Ewan K. A. Millar , Peter H. Graham , Lois Browne , Arcot Sowmya , Erik Meijering

Pancreatic cancers have one of the worst prognoses compared to other cancers, as they are diagnosed when cancer has progressed towards its latter stages. The current manual histological grading for diagnosing pancreatic adenocarcinomas is…

图像与视频处理 · 电气工程与系统科学 2022-06-20 Biraja Ghoshal , Bhargab Ghoshal , Allan Tucker

Background: Transrectal ultrasound guided systematic biopsies of the prostate is a routine procedure to establish a prostate cancer diagnosis. However, the 10-12 prostate core biopsies only sample a relatively small volume of the prostate,…

图像与视频处理 · 电气工程与系统科学 2022-04-20 Bojing Liu , Yinxi Wang , Philippe Weitz , Johan Lindberg , Johan Hartman , Lars Egevad , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

Deep neural networks are starting to show their worth in critical applications such as assisted cancer diagnosis. However, for their outputs to get accepted in practice, the results they provide should be explainable in a way easily…

计算机视觉与模式识别 · 计算机科学 2025-12-22 Martin Krebs , Jan Obdržálek , Vít Musil , Tomáš Brázdil

Prostate cancer is among the most common cancer in males and its heterogeneity is well known. Its early detection helps making therapeutic decision. There is no standard technique or procedure yet which is full-proof in predicting cancer…

机器学习 · 计算机科学 2018-12-18 Khalid Raza , Atif N Hasan

Skin cancer is also one of the most common and dangerous types of cancer in the world that requires timely and precise diagnosis. In this paper, a deep-learning architecture of the multi-class skin lesion classification on the HAM10000…

计算机视觉与模式识别 · 计算机科学 2026-01-06 Md. Maksudul Haque , Rahnuma Akter , A S M Ahsanul Sarkar Akib , Abdul Hasib

This research presents an innovative approach to cancer diagnosis and prediction using explainable Artificial Intelligence (XAI) and deep learning techniques. With cancer causing nearly 10 million deaths globally in 2020, early and accurate…

人工智能 · 计算机科学 2024-12-24 Badaru I. Olumuyiwa , The Anh Han , Zia U. Shamszaman

Prostate cancer is one of the most prevalent cancers worldwide. One of the key factors in reducing its mortality is based on early detection. The computer-aided diagnosis systems for this task are based on the glandular structural analysis…

图像与视频处理 · 电气工程与系统科学 2021-05-25 Julio Silva-Rodríguez , Elena Payá-Bosch , Gabriel García , Adrián Colomer , Valery Naranjo

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

图像与视频处理 · 电气工程与系统科学 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

Radiology reporting generative AI holds significant potential to alleviate clinical workloads and streamline medical care. However, achieving high clinical accuracy is challenging, as radiological images often feature subtle lesions and…

计算机视觉与模式识别 · 计算机科学 2024-11-19 Yijian Gao , Dominic Marshall , Xiaodan Xing , Junzhi Ning , Giorgos Papanastasiou , Guang Yang , Matthieu Komorowski

We investigate the connection between visual semantic features defined in PI-RADS and associated risk factors, moving beyond abnormal imaging findings, establishing a shared framework between medical and AI professionals by creating a…

We present a method for classifying the expertise of a pathologist based on how they allocated their attention during a cancer reading. We engage this decoding task by developing a novel method for predicting the attention of pathologists…

Prostate cancer (PCa) is the second deadliest form of cancer in males, and it can be clinically graded by examining the structural representations of Gleason tissues. This paper proposes \RV{a new method} for segmenting the Gleason tissues…

计算机视觉与模式识别 · 计算机科学 2021-07-27 Taimur Hassan , Bilal Hassan , Ayman El-Baz , Naoufel Werghi