相关论文: Comparative Performance Analysis of Crystals in To…
Background: Total-Body imaging offers high sensitivity, single-bed position, and low dose, but high construction costs limit worldwide utilization. This study compares existing and developing tomographs using plastic scintillators via…
A systematic study is conducted to understand the coincident resolving time (CRT) for a pair of Lutetium-yttrium oxyorthosilicate (LYSO) and the plastic scintillation detector bars under the Geant4 framework. Crystals are coupled to a…
Total Body PET (TBPET) scanners have the potential to substantially reduce both acquisition time and administered radiation dose, owing to their high sensitivity. However, their widespread clinical adoption is hindered by the high cost of…
Objective. This study investigates the best achievable performance of a brain-dedicated PET system with high resolution and sensitivity by evaluating different detector configurations, while maintaining a practical system design suitable…
Total Body PET (TBPET) scanners have recently demonstrated the ability to significantly reduce both acquisition time and the administered radioactive dose, thanks to their increased sensitivity. However, their widespread adoption is limited…
The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…
The measurement of the time of flight of the two 511 keV gammas recorded in coincidence in a PET scanner provides an effective way of reducing the random background and therefore increases the scanner sensitivity, provided that the…
Positron Emission Tomography (PET) using time-of-flight information, which can greatly improve the quality of the reconstructed image, has recently become an exciting topic. In this work, 3.2mm*3.2mm*25mm finger-like LYSO crystals were used…
Liquid xenon time projection chambers offer a homogeneous detection medium with excellent intrinsic energy resolution, fast scintillation, and true three-dimensional position sensitivity, making them an attractive alternative to…
The aim of this study was to optimize the design of a monolithic LGSO scintillation crystal and micro parallel-hole collimator for the development of a small-animal single photon emission computed tomography (SPECT) system with compact…
Total-Body PET is one of the most promising medical diagnostics modalities. The high sensitivity provided by Total-Body technology can be advantageous for novel tomography methods like positronium imaging. Several efforts are ongoing to…
This paper describes the characterization of crystal matrices and silicon photomultiplier arrays for a novel Positron Emission Tomography (PET) detector, namely the external plate of the EndoTOFPET-US system. The EndoTOFPET-US collaboration…
The TT-PET collaboration is developing a small animal TOF-PET scanner based on silicon detectors featuring 30 ps RMS time resolution and intended to be inserted in an existing MRI scanner. The TT-PET scanner makes use of a stack of layers…
Total-body positron emission tomography (PET) imaging has the potential to transform medical care of a number of diseases and augment our knowledge of systems biology. Various detector designs and geometries are currently under development…
The purpose of the presented research is estimation of the performance characteristics of the economic Total-Body Jagiellonian-PET system (TB-J-PET) constructed from plastic scintillators. The characteristics are estimated according to the…
Monte Carlo simulation plays an important role in the study of time of flight (TOF) positron emission tomography (PET) prototype. As it can incorporate accurate physical modeling of scintillation detection process, from scintillation light…
We report on the measurements performed using a 22Na source on a detector element for an MRI-compatible TOF-PET endorectal prostate probe, with Depth-Of-Interaction sensitivity. It is made from a LYSO scintillator crystal, wrapped with…
The foreseen CaLIPSO Positron Emission Tomography (PET) scanner is expected to yield simultaneously a fine image resolution, about 1 mm$^3$, and a high contrast. In this paper we present results of simulations for the full CaLIPSO PET…
Coincidence time resolution (CTR) in time-of-flight positron emission tomography (TOF-PET) has significantly improved with advancements in scintillators, photodetectors, and readout electronics. Achieving a CTR of 100 ps remains challenging…
In living organisms the positron-electron annihilation (occurring during the PET imaging) proceeds in about 30% via creation of a metastable ortho-positronium atom. In the tissue, due to the pick-off and conversion processes, over 98% of…