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This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

计算与语言 · 计算机科学 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Large Language Models (LLMs) have shown remarkable progress in medical question answering (QA), yet their effectiveness remains predominantly limited to English due to imbalanced multilingual training data and scarce medical resources for…

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

计算与语言 · 计算机科学 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

In this paper, we investigate the retrieval-augmented generation (RAG) based on Knowledge Graphs (KGs) to improve the accuracy and reliability of Large Language Models (LLMs). Recent approaches suffer from insufficient and repetitive…

计算与语言 · 计算机科学 2024-04-22 Xinke Jiang , Ruizhe Zhang , Yongxin Xu , Rihong Qiu , Yue Fang , Zhiyuan Wang , Jinyi Tang , Hongxin Ding , Xu Chu , Junfeng Zhao , Yasha Wang

Large Language Models (LLMs) have exhibited impressive generation capabilities, but they suffer from hallucinations when solely relying on their internal knowledge, especially when answering questions that require less commonly known…

计算与语言 · 计算机科学 2023-11-01 Wenting Zhao , Ye Liu , Tong Niu , Yao Wan , Philip S. Yu , Shafiq Joty , Yingbo Zhou , Semih Yavuz

Large Language Models (LLMs) have demonstrated remarkable capabilities in text generation and understanding, yet their reliance on implicit, unstructured knowledge often leads to factual inaccuracies and limited interpretability. Knowledge…

计算与语言 · 计算机科学 2025-06-17 Qinggang Zhang

Large Language Models (LLMs) have recently emerged as a powerful paradigm for Knowledge Graph Completion (KGC), offering strong reasoning and generalization capabilities beyond traditional embedding-based approaches. However, existing…

计算与语言 · 计算机科学 2025-10-14 Wenbin Guo , Xin Wang , Jiaoyan Chen , Lingbing Guo , Zhao Li , Zirui Chen

Large Language Models (LLMs) excel at language understanding but remain limited in knowledge-intensive domains due to hallucinations, outdated information, and limited explainability. Text-based retrieval-augmented generation (RAG) helps…

计算与语言 · 计算机科学 2026-02-09 Larissa Pusch , Alexandre Courtiol , Tim Conrad

Large language models (LLMs) have demonstrated significant potential in clinical decision support. Yet LLMs still suffer from hallucinations and lack fine-grained contextual medical knowledge, limiting their high-stake healthcare…

计算与语言 · 计算机科学 2025-04-22 Pengcheng Jiang , Cao Xiao , Minhao Jiang , Parminder Bhatia , Taha Kass-Hout , Jimeng Sun , Jiawei Han

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

计算与语言 · 计算机科学 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

计算与语言 · 计算机科学 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Large language models (LLMs) have recently emerged as powerful tools, finding many medical applications. LLMs' ability to coalesce vast amounts of information from many sources to generate a response-a process similar to that of a human…

Medical tasks such as diagnosis and treatment planning require precise and complex reasoning, particularly in life-critical domains. Unlike mathematical reasoning, medical reasoning demands meticulous, verifiable thought processes to ensure…

In recent years, Large Language Models (LLMs) have demonstrated an impressive ability to encode knowledge during pre-training on large text corpora. They can leverage this knowledge for downstream tasks like question answering (QA), even in…

计算与语言 · 计算机科学 2024-06-11 Juraj Vladika , Phillip Schneider , Florian Matthes

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

计算与语言 · 计算机科学 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang

Large language models (LLMs) have demonstrated impressive generative capabilities with the potential to innovate in medicine. However, the application of LLMs in real clinical settings remains challenging due to the lack of factual…

Answering real-world complex queries, such as complex product search, often requires accurate retrieval from semi-structured knowledge bases that involve blend of unstructured (e.g., textual descriptions of products) and structured (e.g.,…

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

人工智能 · 计算机科学 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu
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