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Envelope methodology is succinctly pitched as a class of procedures for increasing efficiency in multivariate analyses without altering traditional objectives \citep[first sentence of page 1]{cook2018introduction}. This description is true…

统计方法学 · 统计学 2020-02-05 Daniel J. Eck

A platform trial is an innovative clinical trial design that uses a master protocol to evaluate multiple treatments, where patients are often assigned to different subsets of treatment arms based on individual characteristics, enrollment…

Background: Pairwise and network meta-analyses using fixed effect and random effects models are commonly applied to synthesise evidence from randomised controlled trials. The models differ in their assumptions and the interpretation of the…

统计方法学 · 统计学 2017-08-04 Shijie Ren , Jeremy E. Oakley , John W. Stevens

Multiple imputation has become one of the standard methods in drawing inferences in many incomplete data applications. Applications of multiple imputation in relatively more complex settings, such as high-dimensional clustered data, require…

统计方法学 · 统计学 2025-04-08 Qiushuang Li , Recai Yucel

We propose a general method to carry out a valid Bayesian analysis of a finite-dimensional `targeted' parameter in the presence of a finite-dimensional nuisance parameter. We apply our methods to causal inference based on estimating…

统计方法学 · 统计学 2026-02-03 Magid Sabbagh , David A. Stephens

An inference procedure is proposed to provide consistent estimators of parameters in a modal regression model with a covariate prone to measurement error. A score-based diagnostic tool exploiting parametric bootstrap is developed to assess…

统计方法学 · 统计学 2024-07-02 Qingyang Liu , Xianzheng Huang

This paper develops new tools to quantify uncertainty in optimal decision making and to gain insight into which variables one should collect information about given the potential cost of measuring a large number of variables. We investigate…

统计方法学 · 统计学 2021-05-11 Yunan Wu , Lan Wang , Haoda Fu

Multiple imputation provides an effective way to handle missing data. When several possible models are under consideration for the data, the multiple imputation is typically performed under a single-best model selected from the candidate…

统计方法学 · 统计学 2018-11-30 Gyuhyeong Goh , Jae Kwang Kim

Bayesian hierarchical Poisson models are an essential tool for analyzing count data. However, designing efficient algorithms to sample from the posterior distribution of the target parameters remains a challenging task for this class of…

统计方法学 · 统计学 2025-02-10 Aldo Gardini , Fedele Greco , Carlo Trivisano

The correct use and interpretation of models depends on several steps, two of which being the calibration by parameter estimation and the analysis of uncertainty. In the biological literature, these steps are seldom discussed together, but…

定量方法 · 定量生物学 2015-08-17 André Chalom , Paulo Inácio de Knegt López de Prado

In mortality modelling, cohort effects are often taken into consideration as they add insights about variations in mortality across different generations. Statistically speaking, models such as the Renshaw-Haberman model may provide a…

统计方法学 · 统计学 2024-08-01 Yiping Guo , Johnny Siu-Hang Li

Typical causal effects are defined based on the marginal distribution of potential outcomes. However, many real-world applications require causal estimands involving the joint distribution of potential outcomes to enable more nuanced…

统计方法学 · 统计学 2026-04-17 Peng Wu , Xiaojie Mao

Deep latent variable models (DLVMs) combine the approximation abilities of deep neural networks and the statistical foundations of generative models. Variational methods are commonly used for inference; however, the exact likelihood of…

机器学习 · 统计学 2018-06-29 Pierre-Alexandre Mattei , Jes Frellsen

Among Bayesian methods, Monte-Carlo dropout provides principled tools for evaluating the epistemic uncertainty of neural networks. Its popularity recently led to seminal works that proposed activating the dropout layers only during…

机器学习 · 计算机科学 2023-02-07 Emanuele Ledda , Giorgio Fumera , Fabio Roli

Expectation propagation is a general prescription for approximation of integrals in statistical inference problems. Its literature is mainly concerned with Bayesian inference scenarios. However, expectation propagation can also be used to…

统计方法学 · 统计学 2018-05-23 P. Hall , I. M. Johnstone , J. T. Ormerod , M. P. Wand , J. C. F. Yu

The authors propose a robust semi-parametric empirical likelihood method to integrate all available information from multiple samples with a common center of measurements. Two different sets of estimating equations are used to improve the…

统计方法学 · 统计学 2012-10-03 Hsiao-Hsuan Wang , Yuehua Wu , Yuejiao Fu , Xiaogang Wang

Nonlinear mixed effects models have received a great deal of attention in the statistical literature in recent years because of their flexibility in handling longitudinal studies, including human immunodeficiency virus viral dynamics,…

统计方法学 · 统计学 2021-09-28 Fernanda L. Schumacher , Dipak K. Dey , Victor H. Lachos

Paired cluster-randomized experiments (pCRTs) are common across many disciplines because there is often natural clustering of individuals, and paired randomization can help balance baseline covariates to improve experimental precision.…

统计方法学 · 统计学 2024-07-03 Charlotte Z. Mann , Adam C. Sales , Johann A. Gagnon-Bartsch

There has been great interest recently in applying nonparametric kernel mixtures in a hierarchical manner to model multiple related data samples jointly. In such settings several data features are commonly present: (i) the related samples…

统计方法学 · 统计学 2017-04-18 Jacopo Soriano , Li Ma

In statistical exercises where there are several candidate models, the traditional approach is to select one model using some data driven criterion and use that model for estimation, testing and other purposes, ignoring the variability of…

统计理论 · 数学 2008-12-18 Snigdhansu Chatterjee , Nitai D. Mukhopadhyay