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Estimating potential outcomes for treatments over time based on observational data is important for personalized decision-making in medicine. However, many existing methods for this task fail to properly adjust for time-varying confounding…

机器学习 · 计算机科学 2026-02-18 Konstantin Hess , Dennis Frauen , Valentyn Melnychuk , Stefan Feuerriegel

The paper explores the capability of continuous-time recurrent neural networks to store and recall precisely timed scores of spike trains. We show (by numerical experiments) that this is indeed possible: within some range of parameters, any…

神经与进化计算 · 计算机科学 2025-07-29 Hugo Aguettaz , Hans-Andrea Loeliger

The disease trajectory for clinical sepsis, in terms of temporal cytokine and phenotypic dynamics, can be interpreted as a random dynamical system. The ability to make accurate predictions about patient state from clinical measurements has…

定量方法 · 定量生物学 2020-07-30 Dale Larie , Gary An , Chase Cockrell

Application of discrete-time survival methods for continuous-time survival prediction is considered. For this purpose, a scheme for discretization of continuous-time data is proposed by considering the quantiles of the estimated event-time…

机器学习 · 统计学 2019-10-16 Håvard Kvamme , Ørnulf Borgan

Incorporating the audio stream enables Video Saliency Prediction (VSP) to imitate the selective attention mechanism of human brain. By focusing on the benefits of joint auditory and visual information, most VSP methods are capable of…

计算机视觉与模式识别 · 计算机科学 2023-03-14 Junwen Xiong , Ganglai Wang , Peng Zhang , Wei Huang , Yufei Zha , Guangtao Zhai

Predictive coding networks are neuroscience-inspired models with roots in both Bayesian statistics and neuroscience. Training such models, however, is quite inefficient and unstable. In this work, we show how by simply changing the temporal…

Marginal structural models are a popular tool for investigating the effects of time-varying treatments, but they require an assumption of no unobserved confounders between the treatment and outcome. With observational data, this assumption…

统计方法学 · 统计学 2021-06-10 Matthew Blackwell , Soichiro Yamauchi

We introduce a neural network conformal prediction method for time series that enhances adaptivity in non-stationary environments. Our approach acts as a neural controller designed to achieve desired target coverage, leveraging auxiliary…

机器学习 · 计算机科学 2024-12-25 Ruipu Li , Alexander Rodríguez

Estimating counterfactual outcomes over time has the potential to unlock personalized healthcare by assisting decision-makers to answer ''what-iF'' questions. Existing causal inference approaches typically consider regular, discrete-time…

机器学习 · 计算机科学 2022-06-17 Nabeel Seedat , Fergus Imrie , Alexis Bellot , Zhaozhi Qian , Mihaela van der Schaar

This paper describes recent development and test implementation of a continuous time recurrent neural network that has been configured to predict rates of change in securities. It presents outcomes in the context of popular technical…

计算金融 · 定量金融 2014-06-05 Christopher S Kirk

Conventional modeling approaches have found limitations in matching the increasingly detailed neural network structures and dynamics recorded in experiments to the diverse brain functionalities. On another approach, studies have…

神经元与认知 · 定量生物学 2017-09-05 Chaofei Hong

Uncertainty quantification of causal effects is crucial for safety-critical applications such as personalized medicine. A powerful approach for this is conformal prediction, which has several practical benefits due to model-agnostic…

This paper introduces a general model called CIPNN - Continuous Indeterminate Probability Neural Network, and this model is based on IPNN, which is used for discrete latent random variables. Currently, posterior of continuous latent…

机器学习 · 计算机科学 2023-03-24 Tao Yang

This article introduces a numerical algorithm that serves as a preliminary step toward solving continuous-time model predictive control (MPC) problems directly without explicit time-discretization. The chief ingredients of the underlying…

最优化与控制 · 数学 2024-01-24 Souvik Das , Siddhartha Ganguly , Muthyala Anjali , Debasish Chatterjee

We propose a new class of parameterizations for spatio-temporal point processes which leverage Neural ODEs as a computational method and enable flexible, high-fidelity models of discrete events that are localized in continuous time and…

机器学习 · 计算机科学 2021-03-19 Ricky T. Q. Chen , Brandon Amos , Maximilian Nickel

Spiking neural networks (SNNs) offer a biologically grounded and energy-efficient alternative to conventional neural architectures; however, they struggle with long-range temporal dependencies due to fixed synaptic and membrane time…

神经与进化计算 · 计算机科学 2026-01-06 Sarim Chaudhry

The pressure of ever-increasing patient demand and budget restrictions make hospital bed management a daily challenge for clinical staff. Most critical is the efficient allocation of resource-heavy Intensive Care Unit (ICU) beds to the…

机器学习 · 计算机科学 2020-11-16 Emma Rocheteau , Pietro Liò , Stephanie Hyland

In this study, we investigate the quantification of the statistical reliability of detected change points (CPs) in time series using a Recurrent Neural Network (RNN). Thanks to its flexibility, RNN holds the potential to effectively…

机器学习 · 统计学 2023-11-28 Tomohiro Shiraishi , Daiki Miwa , Vo Nguyen Le Duy , Ichiro Takeuchi

Parkinson's disease (PD) shows heterogeneous, evolving brain-morphometry patterns. Modeling these longitudinal trajectories enables mechanistic insight, treatment development, and individualized 'digital-twin' forecasting. However, existing…

Causal inference in continuous-time sequential decision problems is challenged by hidden confounders. We show that, in latent state-space models with time-varying interventions, observability of the latent dynamics from observed data is…

机器学习 · 计算机科学 2026-05-14 Jennifer Wendland , Nicolas Freitag , Maik Kschischo
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