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The International Symposium on Biomedical Imaging (ISBI) held a grand challenge to evaluate computational systems for the automated detection of metastatic breast cancer in whole slide images of sentinel lymph node biopsies. Our team won…

定量方法 · 定量生物学 2016-06-21 Dayong Wang , Aditya Khosla , Rishab Gargeya , Humayun Irshad , Andrew H. Beck

The appearance of microcalcifications in mammograms is one of the early signs of breast cancer. So, early detection of microcalcification clusters (MCCs) in mammograms can be helpful for cancer diagnosis and better treatment of breast…

计算机视觉与模式识别 · 计算机科学 2012-01-31 Hajar Moradmand , Saeed Setayeshi , Hossein Khazaei Targhi

Vascular adhesion of circulating tumor cells (CTCs) is a key step in cancer spreading. If inflammation is recognized to favor the formation of vascular metastatic niches, little is known about the contribution of blood rheology to CTC…

Biopsies are the gold standard for breast cancer diagnosis. This task can be improved by the use of Computer Aided Diagnosis (CAD) systems, reducing the time of diagnosis and reducing the inter and intra-observer variability. The advances…

计算机视觉与模式识别 · 计算机科学 2019-05-30 Jonathan de Matos , Alceu de S. Britto , Luiz E. S. de Oliveira , Alessandro L. Koerich

Breast cancer is the most diagnosed cancer and the most predominant cause of death in women worldwide. Imaging techniques such as the breast cancer pathology helps in the diagnosis and monitoring of the disease. However identification of…

图像与视频处理 · 电气工程与系统科学 2019-08-06 Francisco Perdigon Romero , An Tang , Samuel Kadoury

Absolute quantity imaging of biomolecules on a single cell level is critical for measurement assurance in biosciences and bioindustries. While infrared (IR) transmission microscopy is a powerful label-free imaging modality capable of…

定量方法 · 定量生物学 2024-03-29 Yow-Ren Chang , Seong-Min Kim , Young Jong Lee

Acute Leukemia is the most common hematologic malignancy in children and adolescents. A key methodology in the diagnostic evaluation of this malignancy is immunophenotyping based on Multiparameter Flow Cytometry (FCM). However, this…

Each year, the treatment decisions for more than 230,000 breast cancer patients in the U.S. hinge on whether the cancer has metastasized away from the breast. Metastasis detection is currently performed by pathologists reviewing large…

Addressing the critical need for accurate prognostic biomarkers in cancer treatment, quantifying tumor-infiltrating lymphocytes (TILs) in non-small cell lung cancer (NSCLC) presents considerable challenges. Manual TIL quantification in…

Research into mechanisms of hematogenous metastasis has largely become genetic in focus, attempting to understand the molecular basis of `seed-soil' relationships. Preceeding this biological mechanism is the physical process of…

组织与器官 · 定量生物学 2013-09-20 Jacob G. Scott , Alexander G. Fletcher , Philip K. Maini , Alexander R. A. Anderson , Philip Gerlee

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

图像与视频处理 · 电气工程与系统科学 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning

We propose to use a compound of magnetic nanoparticles (20-100 nm) embedded in a flexible polymer (Polydimethylsiloxane PDMS) to filter circulating tumor cells (CTCs). The analysis of CTCs is an emerging tool for cancer biology research and…

The Auto-ICell system, a novel, and cost-effective integrated droplet microfluidic system, is introduced for real-time analysis of single-cell morphology and apoptosis. This system integrates a 3D-printed microfluidic chip with image…

图像与视频处理 · 电气工程与系统科学 2023-11-07 Yuanyuan Wei , Meiai Lin , Shanhang Luo , Syed Muhammad Tariq Abbasi , Liwei Tan , Guangyao Cheng , Bijie Bai , Yi-Ping Ho , Scott Wu Yuan , Ho-Pui Ho

Breast cancer is a disease that threatens many women's life, thus, early and accurate detection plays a key role in reducing the mortality rate. Mammography stands as the reference technique for breast cancer screening; nevertheless, many…

图像与视频处理 · 电气工程与系统科学 2022-02-09 Juan Zuluaga-Gomez , N. Zerhouni , Z. Al Masry , C. Devalland , C. Varnier

Breast cancer (BC) significantly contributes to cancer-related mortality in women, underscoring the criticality of early detection for optimal patient outcomes. A mammography is a key tool for identifying and diagnosing breast…

图像与视频处理 · 电气工程与系统科学 2023-10-31 Muhammad Yaqub , Feng Jinchao

Lung cancer (LC) ranks among the most frequently diagnosed cancers and is one of the most common causes of death for men and women worldwide. Computed Tomography (CT) images are the most preferred diagnosis method because of their low cost…

图像与视频处理 · 电气工程与系统科学 2025-08-11 Mobarak Abumohsen , Enrique Costa-Montenegro , Silvia García-Méndez , Amani Yousef Owda , Majdi Owda

Each woman living in the United States has about 1 in 8 chance of developing invasive breast cancer. The mitotic cell count is one of the most common tests to assess the aggressiveness or grade of breast cancer. In this prognosis,…

计算机视觉与模式识别 · 计算机科学 2022-02-18 Robin Elizabeth Yancey

Microwave-based breast cancer detection has been proposed as a complementary approach to compensate for some drawbacks of existing breast cancer detection techniques. Among the existing microwave breast cancer detection methods, machine…

机器学习 · 统计学 2017-02-27 Hongchao Song , Yunpeng Li , Mark Coates , Aidong Men

Cytology is the branch of pathology which deals with the microscopic examination of cells for diagnosis of carcinoma or inflammatory conditions. Automation in cytology started in the early 1950s with the aim to reduce manual efforts in…

图像与视频处理 · 电气工程与系统科学 2020-03-18 Shyamali Mitra , Nibaran Das , Soumyajyoti Dey , Sukanta Chakrabarty , Mita Nasipuri , Mrinal Kanti Naskar

Accurate identification of breast cancer types plays a critical role in guiding treatment decisions and improving patient outcomes. This paper presents an artificial intelligence enabled tool designed to aid in the identification of breast…

图像与视频处理 · 电气工程与系统科学 2025-05-28 Neil Chaudhary , Zaynah Dhunny