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Clinical predictive algorithms are increasingly being used to form the basis for optimal treatment policies--that is, to enable interventions to be targeted to the patients who will presumably benefit most. Despite taking advantage of…

Randomized controlled trials (RCTs) are the standard for evaluating the effectiveness of clinical interventions. To address the limitations of RCTs on real-world populations, we developed a methodology that uses a large observational…

机器学习 · 计算机科学 2024-10-21 Panayiotis Petousis , David Gordon , Susanne B. Nicholas , Alex A. T. Bui

Recent advances in deep learning (DL) have prompted the development of high-performing early warning score (EWS) systems, predicting clinical deteriorations such as acute kidney injury, acute myocardial infarction, or circulatory failure.…

机器学习 · 计算机科学 2025-02-05 Yuxiao Cheng , Xinxin Song , Ziqian Wang , Qin Zhong , Kunlun He , Jinli Suo

Existing strategies for determining the optimal treatment or monitoring strategy typically assume unlimited access to resources. However, when a health system has resource constraints, such as limited funds, access to medication, or…

应用统计 · 统计学 2019-03-18 Ellen C Caniglia , Eleanor J Murray , Miguel A Hernan , Zach Shahn

Many medical decisions involve the use of dynamic information collected on individual patients toward predicting likely transitions in their future health status. If accurate predictions are developed, then a prognostic mode can identify…

统计方法学 · 统计学 2018-02-22 Aasthaa Bansal , Patrick J. Heagerty

Kidney exchange programs among hospitals in the United States and across European countries improve efficiency by pooling donors and patients on a centralized platform. Sustaining such cooperation requires stability. When the core is empty,…

计算机科学与博弈论 · 计算机科学 2026-02-12 Gergely Csáji , Thánh Nguyen

Clinical decision support tools rooted in machine learning and optimization can provide significant value to healthcare providers, including through better management of intensive care units. In particular, it is important that the patient…

机器学习 · 计算机科学 2021-12-20 Fernando Lejarza , Jacob Calvert , Misty M Attwood , Daniel Evans , Qingqing Mao

Cloud Computing is an emerging area. The main aim of the initial search-and-rescue period after strong earthquakes is to reduce the whole number of mortalities. One main trouble rising in this period is to and the greatest assignment of…

分布式、并行与集群计算 · 计算机科学 2014-01-28 Sukhpal Singh , Rishideep Singh

Modeling infection spread during pandemics is not new, with models using past data to tune simulation parameters for predictions. These help understand the healthcare burden posed by a pandemic and respond accordingly. However, the problem…

系统与控制 · 电气工程与系统科学 2020-10-21 Himanshu Kharkwal , Dakota Olson , Jiali Huang , Abhiraj Mohan , Ankur Mani , Jaideep Srivastava

In critical care, intensivists are required to continuously monitor high dimensional vital signs and lab measurements to detect and diagnose acute patient conditions. This has always been a challenging task. In this study, we propose a…

机器学习 · 计算机科学 2019-01-15 Ziyuan Pan , Hao Du , Kee Yuan Ngiam , Fei Wang , Ping Shum , Mengling Feng

Acute kidney injury (AKI) in critically ill patients is associated with significant morbidity and mortality. Development of novel methods to identify patients with AKI earlier will allow for testing of novel strategies to prevent or reduce…

机器学习 · 计算机科学 2018-11-12 Yikuan Li , Liang Yao , Chengsheng Mao , Anand Srivastava , Xiaoqian Jiang , Yuan Luo

This paper presents an event-driven way finding algorithm for pedestrians in an evacuation scenario, which operates on a graph-based structure. The motivation of each pedestrian is to leave the facility. The events used to redirect…

其他计算机科学 · 计算机科学 2011-03-22 A. U. Kemloh Wagoum , A. Seyfried , S. Holl

Catastrophic transitions, where a system shifts abruptly between alternate steady states, are a generic feature of many nonlinear systems. Recently these regime shift were suggested as the mechanism underlies many ecological catastrophes,…

种群与进化 · 定量生物学 2015-06-11 Haim Weissmann , Nadav M. Shnerb

The opioid epidemic is a crisis that has plagued the United States (US) for decades. One central issue is inequitable access to treatment for opioid use disorder (OUD), which puts certain populations at a higher risk of opioid overdose. We…

物理与社会 · 物理学 2024-03-14 Joyce Luo , Bartolomeo Stellato

Timely evacuation is crucial to disaster response, as people can avoid suffering and loss of lives when a major disaster happens. With the development of sharing economy, ridesharing has the advantage of reducing congestion, saving travel…

最优化与控制 · 数学 2021-07-27 Lingyu Meng , Zhijie Sasha Dong

In this article, we propose a mathematical model -- based on a cellular automaton -- for the redistribution of patients within a network of hospitals with limited available resources, in order to reduce the risks of a local/global collapse…

最优化与控制 · 数学 2021-02-25 Roberta Martucci , Corrado Mascia , Chiara Simeoni , Filippo Tassi

Nowadays, data-centers are largely under-utilized because resource allocation is based on reservation mechanisms which ignore actual resource utilization. Indeed, it is common to reserve resources for peak demand, which may occur only for a…

分布式、并行与集群计算 · 计算机科学 2018-07-03 Francesco Pace , Dimitrios Milios , Damiano Carra , Daniele Venzano , Pietro Michiardi

Public health organizations face the problem of dispensing treatments (i.e., vaccines, antibiotics, and others) to groups of affected populations through "points-of-dispensing" (PODs) during emergency situations, typically in the presence…

最优化与控制 · 数学 2021-05-04 Yijia Wang , Daniel R. Jiang

Disaster response is critical to save lives and reduce damages in the aftermath of a disaster. Fundamental to disaster response operations is the management of disaster relief resources. To this end, a local agency (e.g., a local emergency…

机器学习 · 计算机科学 2023-08-01 Hongzhe Zhang , Xiaohang Zhao , Xiao Fang , Bintong Chen

Predicting the risk of death for chronic patients is highly valuable for informed medical decision-making. This paper proposes a general framework for dynamic prediction of the risk of death of a patient given her hospitalization history,…

统计方法学 · 统计学 2024-10-31 Telmo J. Pérez-Izquierdo , Irantzu Barrio , Cristobal Esteban