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Linear Mixed Models (LMMs) are important tools in statistical genetics. When used for feature selection, they allow to find a sparse set of genetic traits that best predict a continuous phenotype of interest, while simultaneously correcting…

Missing data often result in undesirable bias and loss of efficiency. These issues become substantial when the response mechanism is nonignorable, meaning that the response model depends on unobserved variables. To manage nonignorable…

统计方法学 · 统计学 2024-12-30 Kenji Beppu , Jinung Choi , Kosuke Morikawa , Jongho Im

Sensitivity analysis is important to assess the impact of unmeasured confounding in causal inference from observational studies. The marginal sensitivity model (MSM) provides a useful approach in quantifying the influence of unmeasured…

统计方法学 · 统计学 2025-04-14 Yi Zhang , Wenfu Xu , Zhiqiang Tan

Recently, interest has grown in the use of proxy variables of unobserved confounding for inferring the causal effect in the presence of unmeasured confounders from observational data. One difficulty inhibiting the practical use is finding…

机器学习 · 计算机科学 2024-05-28 Feng Xie , Zhengming Chen , Shanshan Luo , Wang Miao , Ruichu Cai , Zhi Geng

Semiparametric regression offers a flexible framework for modeling non-linear relationships between a response and covariates. A prime example are generalized additive models where splines (say) are used to approximate non-linear functional…

统计理论 · 数学 2018-10-05 Francis K. C. Hui , Chong You , Han Lin Shang , Samuel Müller

In observational studies, the observed association between an exposure and outcome of interest may be distorted by unobserved confounding. Causal sensitivity analysis can be used to assess the robustness of observed associations to…

统计方法学 · 统计学 2025-11-04 Rui Hu , Ted Westling

We provide an approach to exploratory data analysis in matched observational studies with a single intervention and multiple endpoints. In such settings, the researcher would like to explore evidence for actual treatment effects among these…

统计方法学 · 统计学 2025-12-10 Mengqi Lin , Colin Fogarty

Probabilistic forecasts must sum to unity and cannot express ``I don't know.'' Possibility theory relaxes this constraint: a subnormal distribution explicitly measures how much of the plausibility budget remains unassigned, ignorance signal…

应用统计 · 统计学 2026-04-03 John R. Lawson

This pedagogical review examines the use of machine learning methods in finite-population inference for survey sampling, with an emphasis on design-based validity and statistical inference. While flexible prediction tools offer substantial…

统计方法学 · 统计学 2026-05-19 Mehdi Dagdoug , David Haziza

We propose probabilistic Shapley inference (PSI), a novel probabilistic framework to model and infer sufficient statistics of feature attributions in flexible predictive models, via latent random variables whose mean recovers Shapley…

机器学习 · 计算机科学 2025-09-09 Mert Ketenci , Iñigo Urteaga , Victor Alfonso Rodriguez , Noémie Elhadad , Adler Perotte

We introduce several methods for assessing sensitivity to unmeasured confounding in marginal structural models; importantly we allow treatments to be discrete or continuous, static or time-varying. We consider three sensitivity models: a…

统计方法学 · 统计学 2022-10-12 Matteo Bonvini , Edward Kennedy , Valerie Ventura , Larry Wasserman

Large language models (LLMs) have demonstrated impressive capabilities across various tasks, but their performance is highly sensitive to the prompts utilized. This variability poses challenges for accurate assessment and user satisfaction.…

计算与语言 · 计算机科学 2024-10-17 Jingming Zhuo , Songyang Zhang , Xinyu Fang , Haodong Duan , Dahua Lin , Kai Chen

Linear mixed models (LMMs) are used as an important tool in the data analysis of repeated measures and longitudinal studies. The most common form of LMMs utilize a normal distribution to model the random effects. Such assumptions can often…

统计方法学 · 统计学 2016-02-16 Hien D. Nguyen , Geoffrey J. McLachlan

Sensitivity to unmeasured confounding is not typically a primary consideration in designing treated-control comparisons in observational studies. We introduce a framework allowing researchers to optimize robustness to omitted variable bias…

统计方法学 · 统计学 2024-07-19 Melody Huang , Dan Soriano , Samuel D. Pimentel

When epidemiologic studies are conducted in a subset of the population, selection bias can threaten the validity of causal inference. This bias can occur whether or not that selected population is the target population, and can occur even…

统计方法学 · 统计学 2019-06-07 Louisa H. Smith , Tyler J. VanderWeele

Recent papers have introduced a novel approach to explain why a Predictive Process Monitoring (PPM) model for outcome-oriented predictions provides wrong predictions. Moreover, they have shown how to exploit the explanations, obtained using…

机器学习 · 计算机科学 2023-03-28 Williams Rizzi , Chiara Di Francescomarino , Chiara Ghidini , Fabrizio Maria Maggi

In designed experiments and surveys, known laws or design feat ures provide checks on the most relevant aspects of a model and identify the target parameters. In contrast, in most observational studies in the health and social sciences, the…

统计方法学 · 统计学 2010-01-18 Sander Greenland

We study mixture of linear regression (random coefficient) models, which capture population heterogeneity by allowing the regression coefficients to follow an unknown distribution $G^*$. In contrast to common parametric methods that fix the…

统计方法学 · 统计学 2025-07-01 Hansheng Jiang , Adityanand Guntuboyina

Nonignorable missing data, where the probability of missingness depends on unobserved values, presents a significant challenge in statistical analysis. Traditional methods often rely on strong parametric assumptions that are difficult to…

统计方法学 · 统计学 2025-09-19 Yujie Zhao

Selective inference aims at providing valid inference after a data-driven selection of models or hypotheses. It is essential to avoid overconfident results and replicability issues. While significant advances have been made in this area for…

统计方法学 · 统计学 2025-03-14 Matteo D'Alessandro , Magne Thoresen