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Immunohistochemistry (IHC) plays a crucial role in pathology as it detects the over-expression of protein in tissue samples. However, there are still fewer machine learning model studies on IHC's impact on accurate cancer grading. We…

计算机视觉与模式识别 · 计算机科学 2024-05-15 Jun Wang , Yu Mao , Yufei Cui , Nan Guan , Chun Jason Xue

The p16/Ki-67 dual staining method is a new approach for cervical cancer screening with high sensitivity and specificity. However, there are issues of mis-detection and inaccurate recognition when the YOLOv5s algorithm is directly applied…

人工智能 · 计算机科学 2024-12-03 Xiao-Jun Wu , Cai-Jun Zhao , Chun Meng , Hang Wang

It has been shown that for automated PAP-smear image classification, nucleus features can be very informative. Therefore, the primary step for automated screening can be cell-nuclei detection followed by segmentation of nuclei in the…

计算机视觉与模式识别 · 计算机科学 2018-06-26 Srishti Gautam , Harinarayan K. K. , Nirmal Jith , Anil K. Sao , Arnav Bhavsar , Adarsh Natarajan

Cell detection is a fundamental task in computational pathology that can be used for extracting high-level medical information from whole-slide images. For accurate cell detection, pathologists often zoom out to understand the tissue-level…

Ovarian cancer (OC) is one of the most prevalent types of cancer in women. Early and accurate diagnosis is crucial for the survival of the patients. However, the majority of women are diagnosed in advanced stages due to the lack of…

机器学习 · 计算机科学 2024-07-31 Asif Newaz , Abdullah Taharat , Md Sakibul Islam , A. G. M. Fuad Hasan Akanda

Computer vision techniques have advanced significantly in recent years, finding diverse and impactful applications within the medical field. In this paper, we introduce a new framework for the detection of Bethesda cells in Pap smear…

计算机视觉与模式识别 · 计算机科学 2026-04-16 Martin Amster , Camila María Polotto

Cervical cancer remains a significant health problem, especially in developing countries. Early detection is critical for effective treatment. Convolutional neural networks (CNN) have shown promise in automated cervical cancer screening,…

图像与视频处理 · 电气工程与系统科学 2025-06-19 Ach Khozaimi , Isnani Darti , Syaiful Anam , Wuryansari Muharini Kusumawinahyu

Transcriptomic assays such as the PAM50-based ROR-P score guide recurrence risk stratification in non-metastatic, ER-positive, HER2-negative breast cancer but are not universally accessible. Histopathology is routinely available and may…

Multiple instance learning (MIL) has shown significant promise in histopathology whole slide image (WSI) analysis for cancer diagnosis and prognosis. However, the inherent spatial heterogeneity of WSIs presents critical challenges, as…

计算机视觉与模式识别 · 计算机科学 2026-01-13 Junjian Li , Jin Liu , Hulin Kuang , Hailin Yue , Mengshen He , Jianxin Wang

Recent years have seen great advancements in the development of deep learning models for histopathology image analysis in digital pathology applications, evidenced by the increasingly common deployment of these models in both research and…

图像与视频处理 · 电气工程与系统科学 2022-08-09 Veena Kaustaban , Qinle Ba , Ipshita Bhattacharya , Nahil Sobh , Satarupa Mukherjee , Jim Martin , Mohammad Saleh Miri , Christoph Guetter , Amal Chaturvedi

Colorectal cancer (CRC) is one of the most common types of cancer with a high mortality rate. Colonoscopy is the preferred procedure for CRC screening and has proven to be effective in reducing CRC mortality. Thus, a reliable computer-aided…

计算机视觉与模式识别 · 计算机科学 2021-09-15 Kaidong Li , Mohammad I. Fathan , Krushi Patel , Tianxiao Zhang , Cuncong Zhong , Ajay Bansal , Amit Rastogi , Jean S. Wang , Guanghui Wang

In computational cytology, detecting malignancy on whole-slide images is difficult because malignant cells are morphologically diverse yet vanishingly rare amid a vast background of normal cells. Accurate detection of these extremely rare…

计算机视觉与模式识别 · 计算机科学 2026-04-13 Swarnadip Chatterjee , Vladimir Basic , Arrigo Capitanio , Orcun Goksel , Joakim Lindblad

Patch classification models based on deep learning have been utilized in whole-slide images (WSI) of H&E-stained tissue samples to assist pathologists in grading follicular lymphoma patients. However, these approaches still require…

Breast cancer, the second leading cause of cancer-related deaths globally, accounts for a quarter of all cancer cases [1]. To lower this death rate, it is crucial to detect tumors early, as early-stage detection significantly improves…

计算机视觉与模式识别 · 计算机科学 2025-09-26 Samia Saeed , Khuram Naveed

Cervical cancer presents a significant global health challenge, necessitating advanced diagnostic and prognostic approaches for effective treatment. This paper investigates the potential of employing multi-modal medical imaging at various…

医学物理 · 物理学 2024-08-27 Haotian Feng , Emi Yoshida , Ke Sheng

Molecular subtypes of breast cancer are important references to personalized clinical treatment. For cost and labor savings, only one of the patient's paraffin blocks is usually selected for subsequent immunohistochemistry (IHC) to obtain…

In order to support the creation of reliable machine learning models for anomaly detection, this project focuses on preprocessing, enhancing, and organizing a medical imaging dataset. There are two classifications in the dataset: normal and…

图像与视频处理 · 电气工程与系统科学 2024-11-20 Dharanidharan S , Suhitha Renuka S , Ajishi Singh , Sheena Christabel Pravin

Early detection and prognosis of breast cancer are feasible by utilizing histopathological grading of biopsy specimens. This research is focused on detection and grading of nuclear pleomorphism in histopathological images of breast cancer.…

计算机视觉与模式识别 · 计算机科学 2016-12-06 Pegah Faridi , Habibollah Danyali , Mohammad Sadegh Helfroush , Mojgan Akbarzadeh Jahromi

Cervical cancer is a very common and fatal type of cancer in women. Cytopathology images are often used to screen for this cancer. Given that there is a possibility that many errors can occur during manual screening, a computer-aided…

计算机视觉与模式识别 · 计算机科学 2021-11-09 Wanli Liu , Chen Li , Md Mamunur Rahamana , Tao Jiang , Hongzan Sun , Xiangchen Wu , Weiming Hu , Haoyuan Chen , Changhao Sun , Yudong Yao , Marcin Grzegorzek

In histopathology, intelligent diagnosis of Whole Slide Images (WSIs) is essential for automating and objectifying diagnoses, reducing the workload of pathologists. However, diagnostic models often face the challenge of forgetting…

计算机视觉与模式识别 · 计算机科学 2025-03-26 Weixi Zheng , Aoling Huang , Jingping Yuan , Haoyu Zhao , Zhou Zhao , Yongchao Xu , Thierry Géraud