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Solid-state nanopores, nm-sized holes in thin, freestanding membranes, are powerful single-molecule sensors capable of interrogating a wide range of target analytes, from small molecules to large polymers. Interestingly, due to their high…

Solid-state nanopores have received substantial attention in the past years owing to their simplicity and potential applications expected in genomics, sensing, archival information storage, and computing. The underlying sensing technique of…

生物物理 · 物理学 2025-08-27 Muhammad Sajeer P , Manoj M. Varma

Controlled breakdown has recently emerged as a highly accessible technique to fabricate solid-state nanopores. However, in its most common form, controlled breakdown creates a single nanopore at an arbitrary location in the membrane. Here,…

In nanopore technology, the development of multiplexed detection and release platforms with high spatial and temporal resolution remains a significant challenge due to the difficulty in distinguishing signals originating from different…

应用物理 · 物理学 2025-10-16 Ali Douaki , Shukun Weng , Silvia Dante , Nako Nakatsuka , Makusu Tsutsui , Roman Krahne , Denis Garoli

Nanopores in 2D materials are of significant interest in advanced membrane technologies aimed at the sensing and separation of ions and molecules. These applications necessitate 2D nanopores that are precise in size and shape, and abundant…

材料科学 · 物理学 2024-08-20 Dana O. Byrne , Frances I. Allen

Solid-state nanopores offer a powerful platform for nanoscale analysis of individual analytes, including biomolecules and functionalized nanoparticles, by confining them within a precisely defined sensing region. However, their inherently…

Solid-state micro/nanopores play an important role in the sensing field because of their high stability and controllable size. Aiming at problems of complex processes and high costs in pore manufacturing, we propose a convenient and…

化学物理 · 物理学 2024-04-04 Rui Liu , Zhe Liu , Jianfeng Li , Yinghua Qiu

Nanopore sensing is a key technology for single-molecule detection and analysis. Solid-state nanopores have emerged as a versatile platform, since their fabrication allows to engineer their properties by controlling size, shape, and…

Accessing fluid infiltration in nanogranular coatings is an outstanding challenge, of relevance for applications ranging from nanomedicine to catalysis. A sensing platform, allowing to quantify the amount of fluid infiltrated in a…

Reactions at solid-water interfaces play a foundational role in water treatment systems, catalysis, chemical separations, and in predicting chemical fate and transport in the environment. Over the last century, experimental measurements and…

化学物理 · 物理学 2022-12-14 Anastasia G. Ilgen , Kevin Leung , Louise J. Criscenti , Jeffery A. Greathouse

Nanopore-based sensing platforms have transformed single-molecule detection and analysis. The foundation of nanopore translocation experiments lies in conductance measurements, yet existing models, which are largely phenomenological, are…

生物物理 · 物理学 2023-12-19 Arjav Shah , Shakul Pathak , Slaven Garaj , Martin Z. Bazant , Ankur Gupta , Patrick S. Doyle

Here, we propose an easy and robust strategy for the versatile preparation of hybrid plasmonic nanopores by means of controlled deposition of single flakes of MoS2 directly on top of metallic holes. The device is realized on silicon nitride…

Technical challenges in molecule sensing and chemical detection have created an increasing demand for transformative materials with high sensitivity and specificity. Biohybrid nanopores have attracted growing interest as they can ideally…

生物物理 · 物理学 2022-04-05 Francois Sicard , A. Ozgur Yazaydin

Nanopores are both a tool to study single-molecule biophysics and nanoscale ion transport, but also a promising material for desalination or osmotic power generation. Understanding the physics underlying ion transport through nano-sized…

软凝聚态物质 · 物理学 2021-04-02 Sanjin Marion , Michal Macha , Sebastian J. Davis , Andrey Chernev , Aleksandra Radenovic

Nanopores in solid state membranes are a tool able to probe nanofluidic phenomena or can act as a single molecular sensor. They also have diverse applications in filtration, desalination or osmotic power generation. Many of these…

Liquid transport through nanopore is central into many applications, from water purification to biosensing or energy harvesting. Ultimately thin nanopores are of major interest in these applications to increase driving potential and reduce…

流体动力学 · 物理学 2020-10-05 Olivier Liot , Catherine Sempere , Christophe Ybert , Anne-Laure Biance

To bridge the gap between single/isolated pore systems to multi-pore systems, such as membranes/electrodes, we studied an array of nanochannels with varying interchannel spacing that controlled the degree of channel communication. Instead…

流体动力学 · 物理学 2015-01-29 Yoav Green , Sinwook Park , Gilad Yossifon

High-fidelity analysis of translocating biomolecules through nanopores demands shortening the nanocapillary length to a minimal value. Existing nanopores and capillaries, however, inherit a finite length from the parent membranes. Here, we…

Nanofabrication techniques for achieving dimensional control at the nanometer scale are generally equipment-intensive and time-consuming. The use of energetic beams of electrons or ions has placed the fabrication of nanopores in thin…

介观与纳米尺度物理 · 物理学 2014-03-25 Harold Kwok , Kyle Briggs , Vincent Tabard-Cossa

Nanofluidic systems exhibit transport characteristics that have made technological marvels such as desalination, energy harvesting, and highly sensitive biomolecule sensing possible by virtue of their ability to influence small currents due…

流体动力学 · 物理学 2023-08-22 John Sebastian , Yoav Green
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