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With populations ageing, the number of people with dementia worldwide is expected to triple to 152 million by 2050. Seventy percent of cases are due to Alzheimer's disease (AD) pathology and there is a 10-20 year 'pre-clinical' period…

In conventional clinical in-vitro fertilization practices embryos are transferred either at the cleavage or blastocyst stages of development. Cleavage stage transfers, particularly, are beneficial for patients with relatively poor prognosis…

In DNA computing, it is impossible to decide whether a specific hybridization among complex DNA molecules is effective or not within acceptable time. In order to address this common problem, we introduce a new method based on the machine…

Prostate cancer is a prevalent malignancy among men aged 50 and older. Current diagnostic methods primarily rely on blood tests, PSA:Prostate-Specific Antigen levels, and Digital Rectal Examinations (DRE). However, these methods suffer from…

The accelerating shift toward low and ultra-low fertility has intensified the debate over whether countries now undergoing rapid decline are approaching stabilization or entering a more persistent low-fertility regime. Existing projection…

Prostate cancer was the third most common cancer in 2020 internationally, coming after breast cancer and lung cancer. Furthermore, in recent years prostate cancer has shown an increasing trend. According to clinical experience, if this…

We compare a set of convolutional neural network (CNN) architectures for the task of segmenting and detecting human sperm cells in an image taken from a semen sample. In contrast to previous work, samples are not stained or washed to allow…

Embryo selection is one of multiple crucial steps in in-vitro fertilization, commonly based on morphological assessment by clinical embryologists. Although artificial intelligence methods have demonstrated their potential to support embryo…

Heart disease is the leading cause of death worldwide. Currently, 33% of cases are misdiagnosed, and approximately half of myocardial infarctions occur in people who are not predicted to be at risk. The use of Artificial Intelligence could…

Prostate cancer pathology plays a crucial role in clinical management but is time-consuming. Artificial intelligence (AI) shows promise in detecting prostate cancer and grading patterns. We tested an AI-based digital twin of a pathologist,…

Traditional sperm morphology analysis is based on tedious manual annotation. Automated morphology analysis of a high number of sperm requires accurate segmentation of each sperm part and quantitative morphology evaluation. State-of-the-art…

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

The research on mortality is an active area of research for any country where the conclusions are driven from the provided data and conditions. The domain knowledge is an essential but not a mandatory skill (though some knowledge is still…

Prostate cancer (Pca) continues to be a leading cause of cancer-related mortality in men, and the limitations in precision of traditional diagnostic methods such as the Digital Rectal Exam (DRE), Prostate-Specific Antigen (PSA) testing, and…

Infertility is becoming an issue for an increasing number of couples. The most common solution, in vitro fertilization, requires embryologists to carefully examine light microscopy images of human oocytes to determine their developmental…

Divorce is one of the most common social issues in developed countries like in the United States. Almost 50% of the recent marriages turn into an involuntary divorce or separation. While it is evident that people vary to a different extent,…

Cancer is one of the most dangerous diseases to humans, and yet no permanent cure has been developed for it. Breast cancer is one of the most common cancer types. According to the National Breast Cancer foundation, in 2020 alone, more than…

The selection of the optimal embryo for transfer is a critical yet challenging step in in vitro fertilization (IVF), primarily due to its reliance on the manual inspection of extensive time-lapse imaging data. A key obstacle in this process…

Automating human preimplantation embryo grading offers the potential for higher success rates with in vitro fertilization (IVF) by providing new quantitative and objective measures of embryo quality. Current IVF procedures typically use…

Cardiovascular diseases and their associated disorder of heart failure are one of the major death causes globally, being a priority for doctors to detect and predict its onset and medical consequences. Artificial Intelligence (AI) allows…