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The ideas of optimization of learning algorithms in Artificial Neural Networks are reviewed emphasizing generic properties and the online implementations are interpreted from a biological perspective. A simple model of the relevant…

无序系统与神经网络 · 物理学 2017-02-08 N. Caticha , O. Kinouchi

In this paper, we propose a new self-triggered formulation of Model Predictive Control for continuous-time linear networked control systems. Our control approach, which aims at reducing the number of transmitting control samples to the…

最优化与控制 · 数学 2016-09-09 K. Hashimoto , S. Adachi , D. V. Dimarogonas

We provide a novel approach and an exploratory study for modelling life event choices and occurrence from a probabilistic perspective through causal discovery and survival analysis. Our approach is formulated as a bi-level problem. In the…

In many clinical contexts, estimating effects of treatment in time-to-event data is complicated not only by confounding, censoring, and heterogeneity, but also by the presence of a cured subpopulation in which the event of interest never…

统计方法学 · 统计学 2026-02-06 Yuqi Li , Quinn Lanners , Matthew M. Engelhard

Although the notion of diagnostic problem has been extensively investigated in the context of static systems, in most practical applications the behavior of the modeled system is significantly variable during time. The goal of the paper is…

人工智能 · 计算机科学 2013-03-25 Luigi Portinale

Interest in targeted disease prevention has stimulated development of models that assign risks to individuals, using their personal covariates. We need to evaluate these models, and to quantify the gains achieved by expanding a model with…

统计方法学 · 统计学 2009-06-16 Alice S. Whittemore

In neoadjuvant trials on early-stage breast cancer, patients are usually randomized into a control group and a treatment group with an additional target therapy. Early efficacy of the new regimen is assessed via the binary pathological…

统计方法学 · 统计学 2022-04-04 Xiaoqing Tan , Judah Abberbock , Priya Rastogi , Gong Tang

When evaluating the efficacy of social programs and medical treatments using randomized experiments, the estimated overall average causal effect alone is often of limited value and the researchers must investigate when the treatments do and…

应用统计 · 统计学 2013-05-27 Kosuke Imai , Marc Ratkovic

Model explainability is crucial for human users to be able to interpret how a proposed classifier assigns labels to data based on its feature values. We study generalized linear models constructed using sets of feature value rules, which…

机器学习 · 统计学 2023-11-06 Sanjeeb Dash , Soumyadip Ghosh , Joao Goncalves , Mark S. Squillante

Precision medicine is an approach for disease treatment that defines treatment strategies based on the individual characteristics of the patients. Motivated by an open problem in cancer genomics, we develop a novel model that flexibly…

统计方法学 · 统计学 2023-09-04 Matteo Pedone , Raffaele Argiento , Francesco C. Stingo

A treatment policy defines when and what treatments are applied to affect some outcome of interest. Data-driven decision-making requires the ability to predict what happens if a policy is changed. Existing methods that predict how the…

机器学习 · 计算机科学 2023-06-21 Çağlar Hızlı , ST John , Anne Juuti , Tuure Saarinen , Kirsi Pietiläinen , Pekka Marttinen

Causal decomposition depicts a cause-effect relationship that is not based on the concept of prediction, but based on the phase dependence of time series. It has been validated in both stochastic and deterministic systems and is now…

信号处理 · 电气工程与系统科学 2020-08-18 Yi Zhang , Qin Yang , Lifu Zhang , Branko Celler , Steven Su , Peng Xu , Dezhong Yao

Modeling disease progression through multiple stages is critical for clinical decision-making for chronic diseases, e.g., cancer, diabetes, chronic kidney diseases, and so on. Existing approaches often model the disease progression as a…

机器学习 · 计算机科学 2025-03-04 Haoyu Yang , Sanjoy Dey , Pablo Meyer

Consider a subject or unit in a longitudinal biomedical, public health, engineering, economic, or social science study which is being monitored over a possibly random duration. Over time this unit experiences competing recurrent events and…

统计方法学 · 统计学 2024-12-30 Lili Tong , Piaomu Liu , Edsel Pena

The interpretability of complex Machine Learning models is coming to be a critical social concern, as they are increasingly used in human-related decision-making processes such as resume filtering or loan applications. Individuals receiving…

数据库 · 计算机科学 2020-07-10 Naama Boer , Daniel Deutch , Nave Frost , Tova Milo

We introduce a novel modeling approach for time series imputation and forecasting, tailored to address the challenges often encountered in real-world data, such as irregular samples, missing data, or unaligned measurements from multiple…

We propose a dynamic multiplicative factor model for process data, which arise from complex problem-solving items, an emerging testing mode in large-scale educational assessment. The proposed model can be viewed as an extension of the…

统计方法学 · 统计学 2026-02-26 Fangyi Chen , Hok Kan Ling , Zhiliang Ying

Structured additive distributional copula regression allows to model the joint distribution of multivariate outcomes by relating all distribution parameters to covariates. Estimation via statistical boosting enables accounting for…

With cross-disciplinary academic interests increasing and academic advising resources over capacity, the importance of exploring data-assisted methods to support student decision making has never been higher. We build on the findings and…

人工智能 · 计算机科学 2018-12-27 Weijie Jiang , Zachary A. Pardos , Qiang Wei

How to induce differentiated cells into pluripotent cells has elicited researchers' interests for a long time since pluripotent stem cells are able to offer remarkable potential in numerous subfields of biological research. However, the…

分子网络 · 定量生物学 2014-12-09 Jiawei Yan , Pu Zheng , Xingjie Pan
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