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Due to large number of entities in biomedical knowledge bases, only a small fraction of entities have corresponding labelled training data. This necessitates entity linking models which are able to link mentions of unseen entities using…

计算与语言 · 计算机科学 2021-04-12 Rico Angell , Nicholas Monath , Sunil Mohan , Nishant Yadav , Andrew McCallum

Entity linking models have achieved significant success via utilizing pretrained language models to capture semantic features. However, the NIL prediction problem, which aims to identify mentions without a corresponding entity in the…

计算与语言 · 计算机科学 2023-05-26 Fangwei Zhu , Jifan Yu , Hailong Jin , Juanzi Li , Lei Hou , Zhifang Sui

Training a neural network-based biomedical named entity recognition (BioNER) model usually requires extensive and costly human annotations. While several studies have employed multi-task learning with multiple BioNER datasets to reduce…

计算与语言 · 计算机科学 2024-12-31 Yu Yin , Hyunjae Kim , Xiao Xiao , Chih Hsuan Wei , Jaewoo Kang , Zhiyong Lu , Hua Xu , Meng Fang , Qingyu Chen

Accurate recognition of biomedical named entities is critical for medical information extraction and knowledge discovery. However, existing methods often struggle with nested entities, entity boundary ambiguity, and cross-lingual…

计算与语言 · 计算机科学 2025-10-13 Tengxiao Lv , Ling Luo , Juntao Li , Yanhua Wang , Yuchen Pan , Chao Liu , Yanan Wang , Yan Jiang , Huiyi Lv , Yuanyuan Sun , Jian Wang , Hongfei Lin

Generative machine learning models offer a powerful framework for therapeutic design by efficiently exploring large spaces of biological sequences enriched for desirable properties. Unlike supervised learning methods, which require both…

Unsupervised learning of generative models has seen tremendous progress over recent years, in particular due to generative adversarial networks (GANs), variational autoencoders, and flow-based models. GANs have dramatically improved sample…

计算机视觉与模式识别 · 计算机科学 2020-01-06 Thomas Lucas , Konstantin Shmelkov , Karteek Alahari , Cordelia Schmid , Jakob Verbeek

We describe a new approach that improves the training of generative adversarial nets (GANs) for synthesizing diverse images from a text input. Our approach is based on the conditional version of GANs and expands on previous work leveraging…

计算机视觉与模式识别 · 计算机科学 2019-02-07 Miriam Cha , Youngjune L. Gwon , H. T. Kung

Generative adversarial networks (GANs) provide an algorithmic framework for constructing generative models with several appealing properties: they do not require a likelihood function to be specified, only a generating procedure; they…

机器学习 · 统计学 2017-02-28 Shakir Mohamed , Balaji Lakshminarayanan

Contextualized word embeddings derived from pre-trained language models (LMs) show significant improvements on downstream NLP tasks. Pre-training on domain-specific corpora, such as biomedical articles, further improves their performance.…

计算与语言 · 计算机科学 2019-04-05 Qiao Jin , Bhuwan Dhingra , William W. Cohen , Xinghua Lu

Recommender systems are popular tools for information retrieval tasks on a large variety of web applications and personalized products. In this work, we propose a Generative Adversarial Network based recommendation framework using a…

信息检索 · 计算机科学 2020-12-15 Yao Zhou , Jianpeng Xu , Jun Wu , Zeinab Taghavi Nasrabadi , Evren Korpeoglu , Kannan Achan , Jingrui He

Consider learning a generative model for time-series data. The sequential setting poses a unique challenge: Not only should the generator capture the conditional dynamics of (stepwise) transitions, but its open-loop rollouts should also…

机器学习 · 统计学 2023-11-03 Daniel Jarrett , Ioana Bica , Mihaela van der Schaar

In the years since Goodfellow et al. introduced Generative Adversarial Networks (GANs), there has been an explosion in the breadth and quality of generative model applications. Despite this work, GANs still have a long way to go before they…

机器学习 · 计算机科学 2020-04-14 Conor Lazarou

Pretraining DNA language models (DNALMs) on the full human genome is resource-intensive, yet often considered necessary for strong downstream performance. Inspired by recent findings in NLP and long-context modeling, we explore an…

基因组学 · 定量生物学 2025-06-24 Sohan Mupparapu , Parameswari Krishnamurthy , Ratish Puduppully

Recent named entity recognition (NER) models often rely on human-annotated datasets, requiring the significant engagement of professional knowledge on the target domain and entities. This research introduces an ask-to-generate approach that…

计算与语言 · 计算机科学 2022-11-08 Hyunjae Kim , Jaehyo Yoo , Seunghyun Yoon , Jinhyuk Lee , Jaewoo Kang

Training on model-generated synthetic data is a promising approach for finetuning LLMs, but it remains unclear when it helps or hurts. In this paper, we investigate this question for math reasoning via an empirical study, followed by…

机器学习 · 计算机科学 2024-06-21 Amrith Setlur , Saurabh Garg , Xinyang Geng , Naman Garg , Virginia Smith , Aviral Kumar

Multimodal Large Language Models (MLLMs) have shown transformative potential in medical applications, yet their performance is hindered by conventional data curation strategies that rely on coarse-grained partitioning by modality or…

计算与语言 · 计算机科学 2026-04-29 Jianghang Lin , Haihua Yang , Deli Yu , Kai Wu , Kai Ye , Jinghao Lin , Zihan Wang , Yuhang Wu , Liujuan Cao

Training robust deep learning (DL) systems for medical image classification or segmentation is challenging due to limited images covering different disease types and severity. We propose an active learning (AL) framework to select most…

计算机视觉与模式识别 · 计算机科学 2019-10-23 Dwarikanath Mahapatra , Behzad Bozorgtabar , Jean-Philippe Thiran , Mauricio Reyes

Using language models (LMs) pre-trained in a self-supervised setting on large corpora and then fine-tuning for a downstream task has helped to deal with the problem of limited label data for supervised learning tasks such as Named Entity…

计算与语言 · 计算机科学 2023-08-21 Pavlova Vera , Mohammed Makhlouf

Named Entity Recognition (NER) is a fundamental Natural Language Processing (NLP) task to extract entities from unstructured data. The previous methods for NER were based on machine learning or deep learning. Recently, pre-training models…

计算与语言 · 计算机科学 2020-02-21 Yu Wang , Yining Sun , Zuchang Ma , Lisheng Gao , Yang Xu , Ting Sun

Biomedical entity linking and event extraction are two crucial tasks to support text understanding and retrieval in the biomedical domain. These two tasks intrinsically benefit each other: entity linking disambiguates the biomedical…

计算与语言 · 计算机科学 2023-05-25 Xiaochu Li , Minqian Liu , Zhiyang Xu , Lifu Huang