中文
相关论文

相关论文: Weak instruments in multivariable Mendelian random…

200 篇论文

Instrumental variables are a popular study design for the estimation of treatment effects in the presence of unobserved confounders. In the canonical instrumental variables design, the instrument is a binary variable. In many settings,…

统计方法学 · 统计学 2024-10-10 Prabrisha Rakshit , Alexander Levis , Luke Keele

Many weak instrumental variables (IVs) are routinely used in the health and social sciences to improve identification and inference of the treatment effect of interest, along with a broad collection of data on potential confounding factors…

统计方法学 · 统计学 2026-04-16 Di Zhang , Xuanyu Li , Baoluo Sun

We expand Mendelian Randomization (MR) methodology to deal with randomly missing data on either the exposure or the outcome variable, and furthermore with data from nonindependent individuals (eg components of a family). Our method rests on…

We provide an overview of results relating to estimation and weak-instrument-robust inference in instrumental variables regression. Methods are implemented in the ivmodels software package for Python, which we use to illustrate results.

计量经济学 · 经济学 2025-08-19 Malte Londschien

Multi-output regression seeks to borrow strength and leverage commonalities across different but related outputs in order to enhance learning and prediction accuracy. A fundamental assumption is that the output/group membership labels for…

机器学习 · 统计学 2023-07-04 Seokhyun Chung , Raed Al Kontar , Zhenke Wu

The accurate labeling of datasets is often both costly and time-consuming. Given an unlabeled dataset, programmatic weak supervision obtains probabilistic predictions for the labels by leveraging multiple weak labeling functions (LFs) that…

机器学习 · 统计学 2025-08-07 Verónica Álvarez , Santiago Mazuelas , Steven An , Sanjoy Dasgupta

The prevalence of one-shot devices is quite prolific in engineering and medical domains. Unlike typical one-shot devices, nondestructive one-shot devices (NOSD) may survive multiple tests and offer additional data for reliability…

统计方法学 · 统计学 2025-02-11 Shanya Baghel , Shuvashree Mondal

Instrumental variable methods have been widely used to identify causal effects in the presence of unmeasured confounding. A key identification condition known as the exclusion restriction states that the instrument cannot have a direct…

统计方法学 · 统计学 2022-08-05 Baoluo Sun , Yifan Cui , Eric Tchetgen Tchetgen

For the over-identified linear instrumental variables model, researchers commonly report the 2SLS estimate along with the robust standard error and seek to conduct inference with these quantities. If errors are homoskedastic, one can…

计量经济学 · 经济学 2023-11-28 David S. Lee , Justin McCrary , Marcelo J. Moreira , Jack Porter , Luther Yap

In this paper, we study the MUltiple SIgnal Classification (MUSIC) algorithm often used to image small targets when multiple measurement vectors are available. We show that this algorithm may be used when the imaging problem can be cast as…

数值分析 · 数学 2019-01-23 Miguel Moscoso , Alexei Novikov , George Papanicolaou , Chrysoula Tsogka

Variational inference is a powerful tool for approximate inference. However, it mainly focuses on the evidence lower bound as variational objective and the development of other measures for variational inference is a promising area of…

机器学习 · 计算机科学 2016-12-06 Michael Figurnov , Kirill Struminsky , Dmitry Vetrov

Instrumental variable methods are among the most commonly used causal inference approaches to deal with unmeasured confounders in observational studies. The presence of invalid instruments is the primary concern for practical applications,…

统计方法学 · 统计学 2023-04-18 Zijian Guo

Panel data methods are widely used in empirical analysis to address unobserved heterogeneity, but causal inference remains challenging when treatments are endogenous and confounding variables high-dimensional and potentially nonlinear.…

计量经济学 · 经济学 2026-03-24 Anna Baiardi , Paul S. Clarke , Andrea A. Naghi , Annalivia Polselli

To conduct Bayesian inference with large data sets, it is often convenient or necessary to distribute the data across multiple machines. We consider a likelihood function expressed as a product of terms, each associated with a subset of the…

统计计算 · 统计学 2020-04-09 Lewis J. Rendell , Adam M. Johansen , Anthony Lee , Nick Whiteley

In instrumental variable (IV) settings, such as in imperfect randomized trials and observational studies with Mendelian randomization, one may encounter a continuous exposure, the causal effect of which is not of true interest. Instead,…

统计方法学 · 统计学 2024-02-01 Erin E. Gabriel , Michael C. Sachs , Arvid Sjölander

The instrumental variable method is widely used in the health and social sciences for identification and estimation of causal effects in the presence of potentially unmeasured confounding. In order to improve efficiency, multiple…

统计方法学 · 统计学 2022-04-19 Baoluo Sun , Zhonghua Liu , Eric Tchetgen Tchetgen

In observational studies, instrumental variable (IV) methods are commonly applied when there exists some unmeasured covariates. In Mendelian Randomization (MR), constructing an allele score by using many single nucleotide polymorphisms…

统计方法学 · 统计学 2022-08-22 Shunichiro Orihara

In this paper, we discuss causal inference on the efficacy of a treatment or medication on a time-to-event outcome with competing risks. Although the treatment group can be randomized, there can be confoundings between the compliance and…

统计方法学 · 统计学 2016-12-06 Cheng Zheng , Ran Dai , Parameswaran Hari , Mei-Jie Zhang

We consider the challenging problem of estimating causal effects from purely observational data in the bi-directional Mendelian randomization (MR), where some invalid instruments, as well as unmeasured confounding, usually exist. To address…

统计方法学 · 统计学 2024-07-15 Feng Xie , Zhen Yao , Lin Xie , Yan Zeng , Zhi Geng

This paper presents a simple method for carrying out inference in a wide variety of possibly nonlinear IV models under weak assumptions. The method is non-asymptotic in the sense that it provides a finite sample bound on the difference…

计量经济学 · 经济学 2018-09-12 Joel L. Horowitz