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Computational pathology has made significant progress in recent years, fueling advances in both fundamental disease understanding and clinically ready tools. This evolution is driven by the availability of large amounts of digitized slides…

Mitotic figure detection in histology images is a hard-to-define, yet clinically significant task, where labels are generated with pathologist interpretations and where there is no ``gold-standard'' independent ground-truth. However, it is…

计算机视觉与模式识别 · 计算机科学 2023-10-09 Cagla Deniz Bahadir , Benjamin Liechty , David J. Pisapia , Mert R. Sabuncu

The diffusion model has recently emerged as a potent approach in computer vision, demonstrating remarkable performances in the field of generative artificial intelligence. Capable of producing high-quality synthetic images, diffusion models…

图像与视频处理 · 电气工程与系统科学 2025-05-14 Abdullah , Tao Huang , Ickjai Lee , Euijoon Ahn

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

图像与视频处理 · 电气工程与系统科学 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

In the complex landscape of hematologic samples such as peripheral blood or bone marrow, cell classification, delineating diverse populations into a hierarchical structure, presents profound challenges. This study presents LeukoGraph, a…

机器学习 · 计算机科学 2024-03-01 Fatemeh Nassajian Mojarrad , Lorenzo Bini , Thomas Matthes , Stéphane Marchand-Maillet

Graph-based representation approaches have been proven to be successful in the analysis of biomedical data, due to their capability of capturing intricate dependencies between biological entities, such as the spatial organization of…

机器学习 · 计算机科学 2023-10-11 Manuel Madeira , Dorina Thanou , Pascal Frossard

Digital pathology plays a vital role across modern medicine, offering critical insights for disease diagnosis, prognosis, and treatment. However, histopathology images often contain artifacts introduced during slide preparation and…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Zhenzhen Wang , Zhongliang Zhou , Zhuoyu Wen , Jeong Hwan Kook , John B Wojcik , John Kang

Efficient detection and classification of blood cells are vital for accurate diagnosis and effective treatment of blood disorders. This study utilizes a YOLOv10 model trained on Roboflow data with images resized to 640x640 pixels across…

图像与视频处理 · 电气工程与系统科学 2025-08-19 Shilpa Choudhary , Sandeep Kumar , Pammi Sri Siddhaarth , Guntu Charitasri

Generative models, especially Diffusion Models, have demonstrated remarkable capability in generating high-quality synthetic data, including medical images. However, traditional class-conditioned generative models often struggle to generate…

计算机视觉与模式识别 · 计算机科学 2025-10-21 Nusrat Munia , Abdullah Imran

Recent progress in generative models has made it easier for a wide audience to edit and create image content, raising concerns about the proliferation of deepfakes, especially in healthcare. Despite the availability of numerous techniques…

图像与视频处理 · 电气工程与系统科学 2024-10-22 Fred Grabovski , Lior Yasur , Guy Amit , Yisroel Mirsky

Cephalometric landmark detection is essential for orthodontic diagnostics and treatment planning. Nevertheless, the scarcity of samples in data collection and the extensive effort required for manual annotation have significantly impeded…

计算机视觉与模式识别 · 计算机科学 2025-05-12 Dongqian Guo , Wencheng Han , Pang Lyu , Yuxi Zhou , Jianbing Shen

Precise segmentation and classification of cell instances are vital for analyzing the tissue microenvironment in histology images, supporting medical diagnosis, prognosis, treatment planning, and studies of brain cytoarchitecture. However,…

计算机视觉与模式识别 · 计算机科学 2025-02-14 Valentina Vadori , Jean-Marie Graïc , Antonella Peruffo , Livio Finos , Ujwala Kiran Chaudhari , Enrico Grisan

White blood cells (WBCs) play a crucial role in safeguarding the human body against pathogens and foreign substances. Leveraging the abundance of WBC imaging data and the power of deep learning algorithms, automated WBC analysis has the…

图像与视频处理 · 电气工程与系统科学 2023-10-23 Aditya Shankar Pal , Debojyoti Biswas , Joy Mahapatra , Debasis Banerjee , Prantar Chakrabarti , Utpal Garain

Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify…

计算机视觉与模式识别 · 计算机科学 2023-11-27 Stefan Röhrl , Johannes Groll , Manuel Lengl , Simon Schumann , Christian Klenk , Dominik Heim , Martin Knopp , Oliver Hayden , Klaus Diepold

Machine learning tasks involving biomedical signals frequently grapple with issues such as limited data availability, imbalanced datasets, labeling complexities, and the interference of measurement noise. These challenges often hinder the…

信号处理 · 电气工程与系统科学 2024-01-30 Xiaomin Li , Mykhailo Sakevych , Gentry Atkinson , Vangelis Metsis

Identifying and characterizing the patient's blood samples is indispensable in diagnostics of malignance suspicious. A painstaking and sometimes subjective task is used in laboratories to manually classify white blood cells. Neural…

图像与视频处理 · 电气工程与系统科学 2020-10-23 Daouda Diouf , Djibril Seck , Mountaga Diop , Abdoulye Ba

Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential…

计算机视觉与模式识别 · 计算机科学 2024-10-04 Lakshmi Nair

Despite fluorescent cell-labelling being widely employed in biomedical studies, some of its drawbacks are inevitable, with unsuitable fluorescent probes or probes inducing a functional change being the main limitations. Consequently, the…

3D spatial graphs play a crucial role in biological and clinical research by modeling anatomical networks such as blood vessels,neurons, and airways. However, generating 3D biological graphs while maintaining anatomical validity remains…

计算机视觉与模式识别 · 计算机科学 2025-07-08 Chinmay Prabhakar , Suprosanna Shit , Tamaz Amiranashvili , Hongwei Bran Li , Bjoern Menze

Hematological disorders, which involve a variety of malignant conditions and genetic diseases affecting blood formation, present significant diagnostic challenges. One such major challenge in clinical settings is differentiating…

图像与视频处理 · 电气工程与系统科学 2024-11-27 Buddhadev Goswami , Adithya B. Somaraj , Prantar Chakrabarti , Ravindra Gudi , Nirmal Punjabi