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Complete randomization allows for consistent estimation of the average treatment effect based on the difference in means of the outcomes without strong modeling assumptions on the outcome-generating process. Appropriate use of the…

统计方法学 · 统计学 2021-08-03 Anqi Zhao , Peng Ding

Personalized medicine has received increasing attention among statisticians, computer scientists, and clinical practitioners. A major component of personalized medicine is the estimation of individualized treatment rules (ITRs). Recently,…

统计方法学 · 统计学 2015-08-14 Xin Zhou , Nicole Mayer-Hamblett , Umer Khan , Michael R. Kosorok

Machine Learning (ML) is increasingly used across many disciplines with impressive reported results. However, recent studies suggest published performance of ML models are often overoptimistic. Validity concerns are underscored by findings…

机器学习 · 计算机科学 2024-07-15 Pouria Saidi , Gautam Dasarathy , Visar Berisha

Clinical decisions to treat and diagnose patients are affected by implicit biases formed by racism, ableism, sexism, and other stereotypes. These biases reflect broader systemic discrimination in healthcare and risk marginalizing already…

机器学习 · 计算机科学 2025-01-29 Kara Liu , Russ Altman , Vasilis Syrgkanis

Estimating nonlinear functionals of probability distributions from samples is a fundamental statistical problem. The "plug-in" estimator obtained by applying the target functional to the empirical distribution of samples is biased.…

统计理论 · 数学 2026-02-20 Florian Schäfer

Every design choice will have different effects on different units. However traditional A/B tests are often underpowered to identify these heterogeneous effects. This is especially true when the set of unit-level attributes is…

人工智能 · 计算机科学 2016-11-09 Alexander Peysakhovich , Akos Lada

Popular guidance on observational data analysis states that outcomes should be blinded when determining matching criteria or propensity scores. Such a blinding is informally said to maintain the "objectivity" of the analysis, and to prevent…

统计方法学 · 统计学 2022-07-26 Aaron Fisher

Automatic Gender Recognition (AGR) systems are an increasingly widespread application in the Machine Learning (ML) landscape. While these systems are typically understood as detecting gender, they often classify datapoints based on…

计算机视觉与模式识别 · 计算机科学 2025-06-04 Camilla Quaresmini , Giacomo Zanotti

We consider the problem of estimating fold-changes in the expected value of a multivariate outcome observed with unknown sample-specific and category-specific perturbations. This challenge arises in high-throughput sequencing studies of the…

统计方法学 · 统计学 2026-04-24 David S Clausen , Sarah Teichman , Amy D Willis

Observational studies can play a useful role in assessing the comparative effectiveness of competing treatments. In a clinical trial the randomization of participants to treatment and control groups generally results in well-balanced groups…

Understanding how treatment effects vary across patient characteristics is essential for personalized medicine, yet randomized controlled trials (RCTs) are often underpowered to detect heterogeneous treatment effects (HTEs). We propose a…

统计方法学 · 统计学 2025-07-22 Amir Asiaee , Chiara Di Gravio , Cole Beck , Yuting Mei , Samhita Pal , Jared D. Huling

Accurate time-to-event prediction is integral to decision-making, informing medical guidelines, hiring decisions, and resource allocation. Survival analysis, the quantitative framework used to model time-to-event data, accounts for patients…

机器学习 · 计算机科学 2025-08-08 Vincent Jeanselme , Brian Tom , Jessica Barrett

One of the primary goals of statistical precision medicine is to learn optimal individualized treatment rules (ITRs). The classification-based, or machine learning-based, approach to estimating optimal ITRs was first introduced in…

统计方法学 · 统计学 2024-06-18 Sophia Yazzourh , Nikki L. B. Freeman

Unbiased recommender learning (URL) and off-policy evaluation/learning (OPE/L) techniques are effective in addressing the data bias caused by display position and logging policies, thereby consistently improving the performance of…

机器学习 · 统计学 2025-02-14 Tatsuki Takahashi , Chihiro Maru , Hiroko Shoji

Meta-analysis is a systematic approach for understanding a phenomenon by analyzing the results of many previously published experimental studies. It is central to deriving conclusions about the summary effect of treatments and interventions…

计算机与社会 · 计算机科学 2021-04-13 Lu Cheng , Dmitriy A. Katz-Rogozhnikov , Kush R. Varshney , Ioana Baldini

Practitioners in diverse fields such as healthcare, economics and education are eager to apply machine learning to improve decision making. The cost and impracticality of performing experiments and a recent monumental increase in electronic…

机器学习 · 计算机科学 2023-08-01 Fredrik D. Johansson , Uri Shalit , Nathan Kallus , David Sontag

Machine learning actively impacts our everyday life in almost all endeavors and domains such as healthcare, finance, and energy. As our dependence on the machine learning increases, it is inevitable that these algorithms will be used to…

机器学习 · 计算机科学 2021-02-23 Ankit Kulshrestha , Ilya Safro

Many modern machine learning algorithms mitigate bias by enforcing fairness constraints across coarsely-defined groups related to a sensitive attribute like gender or race. However, these algorithms seldom account for within-group…

机器学习 · 计算机科学 2023-01-24 Myra Cheng , Maria De-Arteaga , Lester Mackey , Adam Tauman Kalai

Conditioning on some set of confounders that causally affect both treatment and outcome variables can be sufficient for eliminating bias introduced by all such confounders when estimating causal effect of the treatment on the outcome from…

统计方法学 · 统计学 2018-04-24 Priyantha Wijayatunga

Most data for evaluating and training recommender systems is subject to selection biases, either through self-selection by the users or through the actions of the recommendation system itself. In this paper, we provide a principled approach…

机器学习 · 计算机科学 2016-05-30 Tobias Schnabel , Adith Swaminathan , Ashudeep Singh , Navin Chandak , Thorsten Joachims