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Participant recruitment based on unstructured medical texts such as clinical notes and radiology reports has been a challenging yet important task for the cohort establishment in clinical research. Recently, Large Language Models (LLMs)…

计算与语言 · 计算机科学 2023-07-24 Zihan Guan , Zihao Wu , Zhengliang Liu , Dufan Wu , Hui Ren , Quanzheng Li , Xiang Li , Ninghao Liu

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

计算与语言 · 计算机科学 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

The integration of Large Language Models (LLMs) into the healthcare domain has the potential to significantly enhance patient care and support through the development of empathetic, patient-facing chatbots. This study investigates an…

计算与语言 · 计算机科学 2024-05-28 Man Luo , Christopher J. Warren , Lu Cheng , Haidar M. Abdul-Muhsin , Imon Banerjee

Large language models (LLMs) have performed well across various clinical natural language processing tasks, despite not being directly trained on electronic health record (EHR) data. In this work, we examine how popular open-source LLMs…

计算与语言 · 计算机科学 2025-05-26 Furong Jia , David Sontag , Monica Agrawal

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

计算机与社会 · 计算机科学 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Large language models (LLMs) have made significant progress in various domains, including healthcare. However, the specialized nature of clinical language understanding tasks presents unique challenges and limitations that warrant further…

计算与语言 · 计算机科学 2023-08-01 Yuqing Wang , Yun Zhao , Linda Petzold

Recent advancements in large language models (LLMs) have led to the development of highly potent models like OpenAI's ChatGPT. These models have exhibited exceptional performance in a variety of tasks, such as question answering, essay…

计算与语言 · 计算机科学 2023-04-12 Ruixiang Tang , Xiaotian Han , Xiaoqian Jiang , Xia Hu

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Natural language processing (NLP) is a key technology to extract important patient information from clinical narratives to support healthcare applications. The rapid development of large language models (LLMs) has revolutionized many NLP…

计算与语言 · 计算机科学 2025-09-08 Cheng Peng , Xinyu Dong , Mengxian Lyu , Daniel Paredes , Yaoyun Zhang , Yonghui Wu

Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

Large language models (LLMs), such as ChatGPT, have received substantial attention due to their capabilities for understanding and generating human language. While there has been a burgeoning trend in research focusing on the employment of…

The application of large language models (LLMs) in healthcare has gained significant attention due to their ability to process complex medical data and provide insights for clinical decision-making. These models have demonstrated…

计算机视觉与模式识别 · 计算机科学 2024-09-26 Amna Khalid , Ayma Khalid , Umar Khalid

The extraction of critical patient information from Electronic Health Records (EHRs) poses significant challenges due to the complexity and unstructured nature of the data. Traditional machine learning approaches often fail to capture…

计算与语言 · 计算机科学 2025-09-03 Zhimeng Luo , Abhibha Gupta , Adam Frisch , Daqing He

Large Language Models (LLMs) like ChatGPT have demonstrated amazing capabilities in comprehending user intents and generate reasonable and useful responses. Beside their ability to chat, their capabilities in various natural language…

计算与语言 · 计算机科学 2026-02-12 Liz Li , Wei Zhu

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

计算与语言 · 计算机科学 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

The advent of Large Language Models (LLMs) has paved the way for complex tasks such as role-playing, which enhances user interactions by enabling models to imitate various characters. However, the closed-source nature of state-of-the-art…

The identification of key factors such as medications, diseases, and relationships within electronic health records and clinical notes has a wide range of applications in the clinical field. In the N2C2 2022 competitions, various tasks were…

计算与语言 · 计算机科学 2023-06-14 Shouvon Sarker , Lijun Qian , Xishuang Dong

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

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