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This paper addresses the problem of liver cancer segmentation in Whole Slide Image (WSI). We propose a multi-scale image processing method based on automatic end-to-end deep neural network algorithm for segmentation of cancer area. A…

图像与视频处理 · 电气工程与系统科学 2020-07-29 Yanbo Feng , Adel Hafiane , Hélène Laurent

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

图像与视频处理 · 电气工程与系统科学 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

We present a new method for multiclass thresholding of a histogram which is based on the nonparametric Kernel Density (KD) estimation, where the unknown parameters of the KD estimate are defined using the Expectation-Maximization (EM)…

图像与视频处理 · 电气工程与系统科学 2022-02-11 S. Korneev , J. Gilles , I. Battiato

It is clinically crucial and potentially very beneficial to be able to analyze and model directly the spatial distributions of cells in histopathology whole slide images (WSI). However, most existing WSI datasets lack cell-level…

Histologic examination plays a crucial role in oncology research and diagnostics. The adoption of digital scanning of whole slide images (WSI) has created an opportunity to leverage deep learning-based image classification methods to…

计算机视觉与模式识别 · 计算机科学 2024-01-23 Md Zahangir Alom , Quynh T. Tran , Brent A. Orr

Diagnosing diseases through histopathology whole slide images (WSIs) is fundamental in modern pathology but is challenged by the gigapixel scale and complexity of WSIs. Trained histopathologists overcome this challenge by navigating the…

We present a novel neural network Maximum Mean Discrepancy (MMD) statistic by identifying a new connection between neural tangent kernel (NTK) and MMD. This connection enables us to develop a computationally efficient and memory-efficient…

机器学习 · 统计学 2021-10-19 Xiuyuan Cheng , Yao Xie

Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…

Detecting changes is of fundamental importance when analyzing data streams and has many applications, e.g., in predictive maintenance, fraud detection, or medicine. A principled approach to detect changes is to compare the distributions of…

机器学习 · 计算机科学 2025-02-13 Florian Kalinke , Marco Heyden , Georg Gntuni , Edouard Fouché , Klemens Böhm

Whole slide image (WSI) analysis has emerged as an increasingly essential technique in computational pathology. Recent advances in the pathology foundation models (FMs) have demonstrated significant advantages in deriving meaningful…

计算机视觉与模式识别 · 计算机科学 2025-11-21 Zhidong Yang , Xiuhui Shi , Wei Ba , Zhigang Song , Haijing Luan , Taiyuan Hu , Senlin Lin , Jiguang Wang , Shaohua Kevin Zhou , Rui Yan

Few-shot learning is a standard practice in most deep learning based histopathology image segmentation, given the relatively low number of digitized slides that are generally available. While many models have been developed for domain…

图像与视频处理 · 电气工程与系统科学 2021-10-01 Zheng Yuan , Andre Esteva , Ran Xu

In this paper, we introduce a new dataset, \textbf{Kimia Path24}, for image classification and retrieval in digital pathology. We use the whole scan images of 24 different tissue textures to generate 1,325 test patches of size…

计算机视觉与模式识别 · 计算机科学 2017-05-23 Morteza Babaie , Shivam Kalra , Aditya Sriram , Christopher Mitcheltree , Shujin Zhu , Amin Khatami , Shahryar Rahnamayan , H. R. Tizhoosh

Accurate and efficient cell detection is crucial in many biomedical image analysis tasks. We evaluate the performance of several Deep Learning (DL) methods for cell detection in Papanicolaou-stained cytological Whole Slide Images (WSIs),…

计算机视觉与模式识别 · 计算机科学 2026-01-15 Marco Acerbis , Nataša Sladoje , Joakim Lindblad

Tissue segmentation is a routine preprocessing step to reduce the computational cost of whole slide image (WSI) analysis by excluding background regions. Traditional image processing techniques are commonly used for tissue segmentation, but…

图像与视频处理 · 电气工程与系统科学 2024-01-25 Ruben T. Lucassen , Willeke A. M. Blokx , Mitko Veta

Computational pathology has advanced rapidly in recent years, driven by domain-specific image encoders and growing interest in using vision-language models to answer natural-language questions about diseases. Yet, the core problem behind…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Wentao Huang , Weimin Lyu , Peiliang Lou , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Wenchao Han , Ruifeng Guo , Jiawei Zhou , Chao Chen , Chen Wang

Convolutional Neural Network (CNN) models have become the state-of-the-art for most computer vision tasks with natural images. However, these are not best suited for multi-gigapixel resolution Whole Slide Images (WSIs) of histology slides…

计算机视觉与模式识别 · 计算机科学 2017-07-28 Abhinav Agarwalla , Muhammad Shaban , Nasir M. Rajpoot

Much of machine learning relies on comparing distributions with discrepancy measures. Stein's method creates discrepancy measures between two distributions that require only the unnormalized density of one and samples from the other. Stein…

机器学习 · 统计学 2020-07-21 Raghav Singhal , Xintian Han , Saad Lahlou , Rajesh Ranganath

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

图像与视频处理 · 电气工程与系统科学 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

Histopathologists establish cancer grade by assessing histological structures, such as glands in prostate cancer. Yet, digital pathology pipelines often rely on grid-based tiling that ignores tissue architecture. This introduces irrelevant…

Existing WSI analysis methods lie on the consensus that histopathological characteristics of tumors are significant guidance for cancer diagnostics. Particularly, as the evolution of cancers is a continuous process, the correlations and…

计算机视觉与模式识别 · 计算机科学 2024-07-22 Tong Shu , Jun Shi , Dongdong Sun , Zhiguo Jiang , Yushan Zheng
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