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The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

机器学习 · 计算机科学 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Resting-state fMRI has become a valuable tool for classifying brain disorders and constructing brain functional connectivity networks by tracking BOLD signals across brain regions. However, existing mod els largely neglect the…

机器学习 · 计算机科学 2025-11-18 Yue Xun , Jiaxing Xu , Wenbo Gao , Chen Yang , Shujun Wang

Medical imaging datasets are inherently high dimensional with large variability and low sample sizes that limit the effectiveness of deep learning algorithms. Recently, generative adversarial networks (GANs) with the ability to synthesize…

图像与视频处理 · 电气工程与系统科学 2024-12-13 Apoorva Sikka , Skand Peri , Jitender Singh Virk , Usma Niyaz , Deepti R. Bathula

Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the leading cause of dementia, significantly impacting cost, mortality, and burden worldwide. The advent of high-throughput omics technologies, such as genomics,…

信息检索 · 计算机科学 2024-10-16 Liang Tao , Yixin Xie , Jeffrey D Deng , Hui Shen , Hong-Wen Deng , Weihua Zhou , Chen Zhao

Graph Convolutional Networks (GCNs) are pivotal in extracting latent information from graph data across various domains, yet their acceleration on mainstream GPUs is challenged by workload imbalance and memory access irregularity. To…

硬件体系结构 · 计算机科学 2023-08-24 Xi Xie , Hongwu Peng , Amit Hasan , Shaoyi Huang , Jiahui Zhao , Haowen Fang , Wei Zhang , Tong Geng , Omer Khan , Caiwen Ding

For precision medicine and personalized treatment, we need to identify predictive markers of disease. We focus on Alzheimer's disease (AD), where magnetic resonance imaging scans provide information about the disease status. By combining…

机器学习 · 统计学 2019-03-06 Stefan Konigorski , Shahryar Khorasani , Christoph Lippert

Over 30 papers have proposed to use convolutional neural network (CNN) for AD classification from anatomical MRI. However, the classification performance is difficult to compare across studies due to variations in components such as…

Alzheimer diseases (ADs) involves cognitive decline and abnormal brain protein accumulation, necessitating timely diagnosis for effective treatment. Therefore, CAD systems leveraging deep learning advancements have demonstrated success in…

图像与视频处理 · 电气工程与系统科学 2024-05-28 Saddam Hussain Khan

Graph convolutional networks (GCNs), which generalize CNNs to more generic non-Euclidean structures, have achieved remarkable performance for skeleton-based action recognition. However, there still exist several issues in the previous…

计算机视觉与模式识别 · 计算机科学 2020-12-02 Lei Shi , Yifan Zhang , Jian Cheng , Hanqing Lu

Multiple modalities of biomarkers have been proved to be very sensitive in assessing the progression of Alzheimer's disease (AD), and using these modalities and machine learning algorithms, several approaches have been proposed to assist in…

机器学习 · 统计学 2017-12-05 Chen Fang , Panuwat Janwattanapong , Chunfei Li , Malek Adjouadi

There is a need for automatic diagnosis of certain diseases from medical images that could help medical practitioners for further assessment towards treating the illness. Alzheimers disease is a good example of a disease that is often…

图像与视频处理 · 电气工程与系统科学 2019-01-30 GuruRaj Awate

The Blood-Oxygen-Level-Dependent (BOLD) signal of resting-state fMRI (rs-fMRI) records the temporal dynamics of intrinsic functional networks in the brain. However, existing deep learning methods applied to rs-fMRI either neglect the…

机器学习 · 计算机科学 2021-06-30 Soham Gadgil , Qingyu Zhao , Adolf Pfefferbaum , Edith V. Sullivan , Ehsan Adeli , Kilian M. Pohl

We develop three efficient approaches for generating visual explanations from 3D convolutional neural networks (3D-CNNs) for Alzheimer's disease classification. One approach conducts sensitivity analysis on hierarchical 3D image…

计算机视觉与模式识别 · 计算机科学 2018-07-09 Chengliang Yang , Anand Rangarajan , Sanjay Ranka

Alzheimer's disease (AD) has a complex and multifactorial etiology, which requires integrating information about neuroanatomy, genetics, and cerebrospinal fluid biomarkers for accurate diagnosis. Hence, recent deep learning approaches…

机器学习 · 计算机科学 2023-03-15 Tom Nuno Wolf , Sebastian Pölsterl , Christian Wachinger

Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent…

图像与视频处理 · 电气工程与系统科学 2022-02-07 Saman Sotoudeh-Paima , Ata Jodeiri , Fedra Hajizadeh , Hamid Soltanian-Zadeh

Imaging-based early diagnosis of Alzheimer Disease (AD) has become an effective approach, especially by using nuclear medicine imaging techniques such as Positron Emission Topography (PET). In various literature it has been found that PET…

机器学习 · 计算机科学 2021-03-24 Jiaming Guo , Wei Qiu , Xiang Li , Xuandong Zhao , Ning Guo , Quanzheng Li

Graph Convolutional Networks (GCNs) have gained great popularity in tackling various analytics tasks on graph and network data. However, some recent studies raise concerns about whether GCNs can optimally integrate node features and…

机器学习 · 计算机科学 2020-07-14 Xiao Wang , Meiqi Zhu , Deyu Bo , Peng Cui , Chuan Shi , Jian Pei

Brain-related diseases are more sensitive than other diseases due to several factors, including the complexity of surgical procedures, high costs, and other challenges. Alzheimer's disease is a common brain disorder that causes memory loss…

图像与视频处理 · 电气工程与系统科学 2024-03-11 Maleka Khatun , Md Manowarul Islam , Habibur Rahman Rifat , Md. Shamim Bin Shahid , Md. Alamin Talukder , Md Ashraf Uddin

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

图像与视频处理 · 电气工程与系统科学 2024-05-17 Lilia Lazli

Prediction the conversion to early-stage dementia is critical for mitigating its progression but remains challenging due to subtle cognitive impairments and structural brain changes. Traditional T1-weighted magnetic resonance imaging…

计算机视觉与模式识别 · 计算机科学 2024-06-28 Yilin Leng , Wenju Cui , Bai Chen , Xi Jiang , Shuangqing Chen , Jian Zheng