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Accumulated clinical studies show that microbes living in humans interact closely with human hosts, and get involved in modulating drug efficacy and drug toxicity. Microbes have become novel targets for the development of antibacterial…

定量方法 · 定量生物学 2021-08-16 Lei Deng , Yibiao Huang , Xuejun Liu , Hui Liu

Accurate and robust segmentation of abdominal organs on CT is essential for many clinical applications such as computer-aided diagnosis and computer-aided surgery. But this task is challenging due to the weak boundaries of organs, the…

计算机视觉与模式识别 · 计算机科学 2019-04-19 Yan Wang , Yuyin Zhou , Wei Shen , Seyoun Park , Elliot K. Fishman , Alan L. Yuille

Graph representation learning based on graph neural networks (GNNs) can greatly improve the performance of downstream tasks, such as node and graph classification. However, the general GNN models do not aggregate node information in a…

机器学习 · 计算机科学 2020-07-30 Fei Ding , Xiaohong Zhang , Justin Sybrandt , Ilya Safro

Fusing structural-functional images of the brain has shown great potential to analyze the deterioration of Alzheimer's disease (AD). However, it is a big challenge to effectively fuse the correlated and complementary information from…

图像与视频处理 · 电气工程与系统科学 2023-10-06 Qiankun Zuo , Junren Pan , Shuqiang Wang

The recent development of high-throughput sequencing creates a large collection of multi-omics data, which enables researchers to better investigate cancer molecular profiles and cancer taxonomy based on molecular subtypes. Integrating…

基因组学 · 定量生物学 2024-01-25 Bingjun Li , Sheida Nabavi

Clinicians are increasingly looking towards machine learning to gain insights about patient evolutions. We propose a novel approach named Multi-Modal UMLS Graph Learning (MMUGL) for learning meaningful representations of medical concepts…

机器学习 · 计算机科学 2024-02-07 Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Unsupervised graph representation learning aims to learn low-dimensional node embeddings without supervision while preserving graph topological structures and node attributive features. Previous graph neural networks (GNN) require a large…

机器学习 · 计算机科学 2020-09-04 Yanqiao Zhu , Yichen Xu , Feng Yu , Shu Wu , Liang Wang

A large number of real-world graphs or networks are inherently heterogeneous, involving a diversity of node types and relation types. Heterogeneous graph embedding is to embed rich structural and semantic information of a heterogeneous…

社会与信息网络 · 计算机科学 2020-04-01 Xinyu Fu , Jiani Zhang , Ziqiao Meng , Irwin King

Unsupervised multiplex graph learning (UMGL) has been shown to achieve significant effectiveness for different downstream tasks by exploring both complementary information and consistent information among multiple graphs. However, previous…

机器学习 · 计算机科学 2023-08-04 Liang Peng , Xin Wang , Xiaofeng Zhu

The increase in high-dimensional multiomics data demands advanced integration models to capture the complexity of human diseases. Graph-based deep learning integration models, despite their promise, struggle with small patient cohorts and…

机器学习 · 计算机科学 2024-08-07 Sina Tabakhi , Charlotte Vandermeulen , Ian Sudbery , Haiping Lu

Graph neural networks (GNNs) have shown significant success in learning graph representations. However, recent studies reveal that GNNs often fail to outperform simple MLPs on heterophilous graph tasks, where connected nodes may differ in…

机器学习 · 计算机科学 2025-04-10 Songwei Zhao , Yuan Jiang , Zijing Zhang , Yang Yu , Hechang Chen

Omics data facilitate the gain of novel insights into the pathophysiology of diseases and, consequently, their diagnosis, treatment, and prevention. To that end, it is necessary to integrate omics data with other data types such as…

Recent research on graph neural networks (GNNs) has explored mechanisms for capturing local uncertainty and exploiting graph hierarchies to mitigate data sparsity and leverage structural properties. However, the synergistic integration of…

机器学习 · 计算机科学 2025-05-06 Yoonhyuk Choi , Jiho Choi , Taewook Ko , Chong-Kwon Kim

Hyperspectral unmixing (HU) is a critical yet challenging task in remote sensing. However, existing nonnegative matrix factorization (NMF) methods with graph learning mostly focus on first-order or second-order nearest neighbor…

计算机视觉与模式识别 · 计算机科学 2025-09-26 Hui Chen , Liangyu Liu , Xianchao Xiu , Wanquan Liu

Monitoring plantations is crucial for crop management and producing healthy harvests. Unmanned Aerial Vehicles (UAVs) have been used to collect multispectral images that aid in this monitoring. However, given the number of hectares to be…

计算机视觉与模式识别 · 计算机科学 2024-09-17 Felipe A. Lopes , Vasit Sagan , Flavio Esposito

Entity alignment typically suffers from the issues of structural heterogeneity and limited seed alignments. In this paper, we propose a novel Multi-channel Graph Neural Network model (MuGNN) to learn alignment-oriented knowledge graph (KG)…

计算与语言 · 计算机科学 2019-08-28 Yixin Cao , Zhiyuan Liu , Chengjiang Li , Zhiyuan Liu , Juanzi Li , Tat-Seng Chua

In the treatment of complex diseases, treatment regimens using a single drug often yield limited efficacy and can lead to drug resistance. In contrast, combination drug therapies can significantly improve therapeutic outcomes through…

机器学习 · 计算机科学 2026-04-24 Jiyan Song , Wenyang Wang , Chengcheng Yan , Zhiquan Han , Feifei Zhao

We propose a graph neural network (GNN) approach to the problem of predicting the stylistic compatibility of a set of furniture items from images. While most existing results are based on siamese networks which evaluate pairwise…

计算机视觉与模式识别 · 计算机科学 2020-04-17 Luisa F. Polania , Mauricio Flores , Yiran Li , Matthew Nokleby

Unsupervised attributed graph representation learning is challenging since both structural and feature information are required to be represented in the latent space. Existing methods concentrate on learning latent representation via…

机器学习 · 计算机科学 2021-04-28 Zelin Zang , Siyuan Li , Di Wu , Jianzhu Guo , Yongjie Xu , Stan Z. Li

Accurate prediction of molecular properties is essential in drug discovery and related fields. However, existing graph neural networks (GNNs) often struggle to simultaneously capture both local and global molecular structures. In this work,…

机器学习 · 计算机科学 2025-08-26 XiaYu Liu , Chao Fan , Yang Liu , Hou-biao Li