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Diabetic Retinopathy (DR) stands as the leading cause of blindness globally, particularly affecting individuals between the ages of 20 and 70. This paper presents a Computer-Aided Diagnosis (CAD) system designed for the automatic…
Background. Absorbed radiation dose to the mandible is an important risk factor in the development of mandibular osteoradionecrosis (ORN) in head and neck cancer (HNC) patients treated with radiotherapy (RT). The prediction of mandibular…
The development of machine learning systems for the diagnosis of rare diseases is challenging mainly due the lack of data to study them. Despite this challenge, this paper proposes a system for the Computer Aided Diagnosis (CAD) of…
Recent years have witnessed an increasing global population affected by neurodegenerative diseases (NDs), which traditionally require extensive healthcare resources and human effort for medical diagnosis and monitoring. As a crucial…
Ultrasound curve angle (UCA) measurement provides a radiation-free and reliable evaluation for scoliosis based on ultrasound imaging. However, degraded image quality, especially in difficult-to-image patients, can prevent clinical experts…
Out-of-distribution (OOD) detection is critical for the safe deployment of machine learning systems in safety-sensitive domains. Diffusion models have recently emerged as powerful generative models, capable of capturing complex data…
The aim of this study is developing an automatic system for detection of gait-related health problems using Deep Neural Networks (DNNs). The proposed system takes a video of patients as the input and estimates their 3D body pose using a DNN…
Alzheimer's Disease (AD) is a severe brain disorder, destroying memories and brain functions. AD causes chronically, progressively, and irreversibly cognitive declination and brain damages. The reliable and effective evaluation of early…
Kidney allograft fibrosis is a marker of chronic kidney disease (CKD) and predicts functional decline, and eventual allograft failure. This study evaluates if spectral diffusion MRI can help detect early development and mild/moderate…
Optical Coherence Tomography(OCT) is a non-invasive technique capturing cross-sectional area of the retina in micro-meter resolutions. It has been widely used as a auxiliary imaging reference to detect eye-related pathology and predict…
Automatic segmentation of knee bony anatomy is essential in orthopedics, and it has been around for several years in both pre-operative and post-operative settings. While deep learning algorithms have demonstrated exceptional performance in…
Pose skeleton images are an important reference in pose-controllable image generation. In order to enrich the source of skeleton images, recent works have investigated the generation of pose skeletons based on natural language. These…
Parkinson's disease (PD) is a common neurological disorder characterized by gait impairment. PD has no cure, and an impediment to developing a treatment is the lack of any accepted method to predict disease progression rate. The primary aim…
Parkinson's disease (PD) shows heterogeneous, evolving brain-morphometry patterns. Modeling these longitudinal trajectories enables mechanistic insight, treatment development, and individualized 'digital-twin' forecasting. However, existing…
Osteosarcoma is the most common primary bone cancer, mainly affecting the youngest and oldest populations. Its detection at early stages is crucial to reduce the probability of developing bone metastasis. In this context, accurate and fast…
An important goal of medical imaging is to be able to precisely detect patterns of disease specific to individual scans; however, this is challenged in brain imaging by the degree of heterogeneity of shape and appearance. Traditional…
A Convolutional Neural Network was used to predict kidney function in patients with chronic kidney disease from high-resolution digital pathology scans of their kidney biopsies. Kidney biopsies were taken from participants of the NEPTUNE…
Early detection of inflammatory arthritis (IA) is critical to efficient and accurate hospital referral triage for timely treatment and preventing the deterioration of the IA disease course, especially under limited healthcare resources. The…
Osteoporosis is a widespread and chronic metabolic bone disease that often remains undiagnosed and untreated due to limited access to bone mineral density (BMD) tests like Dual-energy X-ray absorptiometry (DXA). In response to this…
Neuro-oncology poses unique challenges for machine learning due to heterogeneous data and tumor complexity, limiting the ability of foundation models (FMs) to generalize across cohorts. Existing FMs also perform poorly in predicting…