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Quantitative phase imaging (QPI) is important in many applications such as microscopy and crystallography. To quantitatively reveal phase information, people could either employ interference to map phase distribution into intensity fringes,…

光学 · 物理学 2020-11-11 Xianye Li , Yafei sun , Yikang He , Xun Li , Baoqing Sun

Characterization of atomic-scale materials traditionally requires human experts with months to years of specialized training. Even for trained human operators, accurate and reliable characterization remains challenging when examining newly…

Polarimetric imaging provides valuable insights into the polarization state of light interacting with a sample. It can infer crucial birefringence properties of bio-specimens without using any labels, thereby facilitating the diagnosis of…

Accurate diagnosis of disease often depends on the exhaustive examination of Whole Slide Images (WSI) at microscopic resolution. Efficient handling of these data-intensive images requires lossy compression techniques. This paper…

Quantitative phase imaging (QPI) is a label-free computational imaging technique that provides optical path length information of specimens. In modern implementations, the quantitative phase image of an object is reconstructed digitally…

光学 · 物理学 2022-05-23 Deniz Mengu , Aydogan Ozcan

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

计算机视觉与模式识别 · 计算机科学 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Motivation: High resolution 2D whole slide imaging provides rich information about the tissue structure. This information can be a lot richer if these 2D images can be stacked into a 3D tissue volume. A 3D analysis, however, requires…

Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

计算机视觉与模式识别 · 计算机科学 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

Fluorescence imaging is an essential diagnostic tool in many fields, but diffraction-limited optical imaging at depth is limited by scattering. Here, we present a method based on multiple random illuminations, combined with a computational…

光学 · 物理学 2026-03-30 Lei Zhu , Tengfei Wu , Bernhard Rauer , Hilton B. de Aguiar , Sylvain Gigan

Ultrasound (US) imaging is an indispensable tool for diagnostic imaging, particularly given its cost, safety, and portability profiles compared to other modalities. However, US is challenged in subjects with morphological heterogeneity…

信号处理 · 电气工程与系统科学 2025-08-19 Scott Schoen , Brian Lause , Marko Jakovljevic , Rimon Tadross , Mike Washburn , Anthony E. Samir

Ptychography, a coherent diffraction imaging technique, has become an indispensable tool in materials characterization, biological imaging, and nanostructure analysis due to its capability for high-resolution, lensless reconstruction of…

We propose a novel method for non-rigid 3-D motion correction of orthogonally raster-scanned optical coherence tomography angiography volumes. This is the first approach that aligns predominantly axial structural features like retinal…

Histopathology image analysis is the golden standard of clinical diagnosis for Cancers. In doctors daily routine and computer-aided diagnosis, the Whole Slide Image (WSI) of histopathology tissue is used for analysis. Because of the…

计算机视觉与模式识别 · 计算机科学 2023-11-23 Honglin Li , Yunlong Zhang , Chenglu Zhu , Jiatong Cai , Sunyi Zheng , Lin Yang

In industrial manufacturing processes, errors frequently occur at unpredictable times and in unknown manifestations. We tackle the problem of automatic defect detection without requiring any image samples of defective parts. Recent works…

计算机视觉与模式识别 · 计算机科学 2021-10-07 Marco Rudolph , Tom Wehrbein , Bodo Rosenhahn , Bastian Wandt

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

图像与视频处理 · 电气工程与系统科学 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

Angular differential imaging is a high-contrast imaging technique that reduces quasi-static speckle noise and facilitates the detection of nearby companions. A sequence of images is acquired with an altitude/azimuth telescope while the…

天体物理学 · 物理学 2009-11-13 C. Marois , D. Lafreniere , R. Doyon , B. Macintosh , D. Nadeau

Whole slide image (WSI) analysis in digital pathology presents unique challenges due to the gigapixel resolution of WSIs and the scarcity of dense supervision signals. While Multiple Instance Learning (MIL) is a natural fit for slide-level…

计算机视觉与模式识别 · 计算机科学 2025-08-21 Sofiène Boutaj , Marin Scalbert , Pierre Marza , Florent Couzinie-Devy , Maria Vakalopoulou , Stergios Christodoulidis

In this paper, we propose a novel method for highly efficient follicular segmentation of thyroid cytopathological WSIs. Firstly, we propose a hybrid segmentation architecture, which integrates a classifier into Deeplab V3 by adding a…

计算机视觉与模式识别 · 计算机科学 2019-02-15 Siyan Tao , Yao Guo , Chuang Zhu , Huang Chen , Yue Zhang , Jie Yang , Jun Liu

Imaging through complex scattering media is severely limited by aberrations and scattering which obscure images and reduce resolution. Confocal and temporal gatings partly filter out multiple scattering but are severely degraded by…

光学 · 物理学 2026-05-18 Yiwen Zhang , Minh Dinh , Zeyu Wang , Tianhao Zhang , Tianhang Chen , Chia Wei Hsu

High-resolution imaging in the terahertz (THz) spectral range remains fundamentally constrained by the limited numerical apertures of currently existing state-of-the-art imagers, which restricts its applicability across many fields, such as…