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Volumetric segmentation of lesions on CT scans is important for many types of analysis, including lesion growth kinetic modeling in clinical trials and machine learning of radiomic features. Manual segmentation is laborious, and impractical…

计算机视觉与模式识别 · 计算机科学 2018-11-13 Bo Zhou , Randolph Crawford , Belma Dogdas , Gregory Goldmacher , Antong Chen

Prostate cancer (PCa) is the most prevalent cancer among men in the United States, accounting for nearly 300,000 cases, 29\% of all diagnoses and 35,000 total deaths in 2024. Traditional screening methods such as prostate-specific antigen…

图像与视频处理 · 电气工程与系统科学 2025-05-27 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

Current deep learning approaches for prostate cancer lesion segmentation achieve limited performance, with Dice scores of 0.32 or lower in large patient cohorts. To address this limitation, we investigate synthetic correlated diffusion…

计算机视觉与模式识别 · 计算机科学 2025-11-12 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

Accurate segmentation of prostate and surrounding organs at risk is important for prostate cancer radiotherapy treatment planning. We present a fully automated workflow for male pelvic CT image segmentation using deep learning. The…

PET imaging is an invaluable tool in clinical settings as it captures the functional activity of both healthy anatomy and cancerous lesions. Developing automatic lesion segmentation methods for PET images is crucial since manual lesion…

图像与视频处理 · 电气工程与系统科学 2024-11-05 Tanya Gatsak , Kumar Abhishek , Hanene Ben Yedder , Saeid Asgari Taghanaki , Ghassan Hamarneh

Purpose: Bone metastasis have a major impact on the quality of life of patients and they are diverse in terms of size and location, making their segmentation complex. Manual segmentation is time-consuming, and expert segmentations are…

图像与视频处理 · 电气工程与系统科学 2024-09-18 Emile Saillard , Aurélie Levillain , David Mitton , Jean-Baptiste Pialat , Cyrille Confavreux , Hélène Follet , Thomas Grenier

This study explores a workflow for automated segmentation of lesions in FDG and PSMA PET/CT images. Due to the substantial differences in image characteristics between FDG and PSMA, specialized preprocessing steps are required. Utilizing…

计算机视觉与模式识别 · 计算机科学 2024-09-17 Qiaoyi Xue , Youdan Feng , Jiayi Liu , Tianming Xu , Kaixin Shen , Chuyun Shen , Yuhang Shi

Prostate cancer represents a major threat to health. Early detection is vital in reducing the mortality rate among prostate cancer patients. One approach involves using multi-modality (CT, MRI, US, etc.) computer-aided diagnosis (CAD)…

图像与视频处理 · 电气工程与系统科学 2024-07-10 Rui Jin , Derun Li , Dehui Xiang , Lei Zhang , Hailing Zhou , Fei Shi , Weifang Zhu , Jing Cai , Tao Peng , Xinjian Chen

Quantitative molecular imaging is central to treatment response assessment in oncology, yet clinical practice remains largely dominated by patient-level or limited target-lesion criteria that ignore inter-lesion heterogeneity. This…

医学物理 · 物理学 2026-03-25 Fereshteh Yousefirizi , Jean-Mathieu Beauregard , Arman Rahmim

Purpose: We aimed to develop deep machine learning (DL) models to improve the detection and segmentation of intraprostatic lesions (IL) on bp-MRI by using whole amount prostatectomy specimen-based delineations. We also aimed to investigate…

图像与视频处理 · 电气工程与系统科学 2020-10-30 Zhenzhen Dai , Ivan Jambor , Pekka Taimen , Milan Pantelic , Mohamed Elshaikh , Craig Rogers , Otto Ettala , Peter Boström , Hannu Aronen , Harri Merisaari , Ning Wen

Positron Emission Tomography (PET) /Computed Tomography (CT) is crucial for diagnosing, managing, and planning treatment for various cancers. Developing reliable deep learning models for the segmentation of tumor lesions in PET/CT scans in…

图像与视频处理 · 电气工程与系统科学 2024-09-24 Tanya Chutani , Saikiran Bonthu , Pranab Samanta , Nitin Singhal

In this work we propose to segment the prostate on a challenging dataset of trans-rectal ultrasound (TRUS) images using convolutional neural networks (CNNs) and statistical shape models (SSMs). TRUS is commonly used for a number of…

图像与视频处理 · 电气工程与系统科学 2021-06-18 Golnoosh Samei , Davood Karimi , Claudia Kesch , Septimiu Salcudean

The detection of clinically significant prostate cancer lesions (csPCa) from biparametric magnetic resonance imaging (bp-MRI) has emerged as a noninvasive imaging technique for improving accurate diagnosis. Nevertheless, the analysis of…

计算机视觉与模式识别 · 计算机科学 2025-11-11 Mateo Ortiz , Juan Olmos , Fabio Martínez

Volumetric lesion segmentation via medical imaging is a powerful means to precisely assess multiple time-point lesion/tumor changes. Because manual 3D segmentation is prohibitively time consuming and requires radiological experience,…

计算机视觉与模式识别 · 计算机科学 2018-01-29 Jinzheng Cai , Youbao Tang , Le Lu , Adam P. Harrison , Ke Yan , Jing Xiao , Lin Yang , Ronald M. Summers

The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…

Prostate cancer was the third most common cancer in 2020 internationally, coming after breast cancer and lung cancer. Furthermore, in recent years prostate cancer has shown an increasing trend. According to clinical experience, if this…

图像与视频处理 · 电气工程与系统科学 2022-08-30 Carlos Nácher Collado

PET and CT are two modalities widely used in medical image analysis. Accurately detecting and segmenting lymphomas from these two imaging modalities are critical tasks for cancer staging and radiotherapy planning. However, this task is…

图像与视频处理 · 电气工程与系统科学 2021-04-28 Ling Huang , Su Ruan , Pierre Decazes , Thierry Denoeux

This paper proposes a two-stage segmentation model, variable-input based uncertainty measures and an uncertainty-guided post-processing method for prostate segmentation on 3D magnetic resonance images (MRI). The two-stage model was based on…

计算机视觉与模式识别 · 计算机科学 2019-03-07 Huitong Pan , Yushan Feng , Quan Chen , Craig Meyer , Xue Feng

The emergence of multi-parametric magnetic resonance imaging (mpMRI) has had a profound impact on the diagnosis of prostate cancers (PCa), which is the most prevalent malignancy in males in the western world, enabling a better selection of…

Automated 3D segmentation of prostate lesions from biparametric MRI (bp-MRI) is essential for reliable algorithmic analysis, but achieving high precision remains challenging. Volumetric methods must combine multiple modalities while…

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