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Large pretrained transformers are increasingly being developed as generalised foundation models which can underpin powerful task-specific artificial intelligence models. Histopathology foundation models show great promise across many tasks,…

图像与视频处理 · 电气工程与系统科学 2024-09-10 Jack Breen , Katie Allen , Kieran Zucker , Lucy Godson , Nicolas M. Orsi , Nishant Ravikumar

Artificial intelligence has found increasing use for ovarian cancer morphological subtyping from histopathology slides, but the optimal magnification for computational interpretation is unclear. Higher magnifications offer abundant…

图像与视频处理 · 电气工程与系统科学 2024-10-28 Jack Breen , Katie Allen , Kieran Zucker , Nicolas M. Orsi , Nishant Ravikumar

Whole-slide images (WSIs) from cancer patients contain rich information that can be used for medical diagnosis or to follow treatment progress. To automate their analysis, numerous deep learning methods based on convolutional neural…

计算机视觉与模式识别 · 计算机科学 2026-02-18 Lucas Sancéré , Noémie Moreau , Katarzyna Bozek

Graph convolutional neural networks have shown significant potential in natural and histopathology images. However, their use has only been studied in a single magnification or multi-magnification with late fusion. In order to leverage the…

计算机视觉与模式识别 · 计算机科学 2023-08-22 Roozbeh Bazargani , Ladan Fazli , Larry Goldenberg , Martin Gleave , Ali Bashashati , Septimiu Salcudean

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

图像与视频处理 · 电气工程与系统科学 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

Histopathological images provide rich information for disease diagnosis. Large numbers of histopathological images have been digitized into high resolution whole slide images, opening opportunities in developing computational image analysis…

图像与视频处理 · 电气工程与系统科学 2020-11-06 Jiayun Li , Wenyuan Li , Anthony Sisk , Huihui Ye , W. Dean Wallace , William Speier , Corey W. Arnold

Breast cancer is the most common cancer type in women worldwide. Early detection and appropriate treatment can significantly reduce its impact. While histopathology examinations play a vital role in rapid and accurate diagnosis, they often…

计算机视觉与模式识别 · 计算机科学 2026-04-28 Nematollah Saeidi , Hossein Karshenas , Bijan Shoushtarian , Sepideh Hatamikia , Ramona Woitek , Amirreza Mahbod

Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…

计算机视觉与模式识别 · 计算机科学 2024-06-11 Akash Modi , Sumit Kumar Jha , Purnendu Mishra , Rajiv Kumar , Kiran Aatre , Gursewak Singh , Shubham Mathur

Early diagnosis of the cancer cells is necessary for making an effective treatment plan and for the health and safety of a patient. Nowadays, doctors usually use a histological grade that pathologists determine by performing a…

计算机视觉与模式识别 · 计算机科学 2023-11-15 Varan Singh Rohila , Neeraj Lalwani , Lochan Basyal

Ovarian cancer remains one of the most lethal gynecological malignancies, largely due to late diagnosis and extensive heterogeneity across subtypes. Current diagnostic methods are limited in their ability to reveal underlying genomic…

图像与视频处理 · 电气工程与系统科学 2025-11-06 Gabriela Fernandes

Colorectal cancer (CRC) grading is typically carried out by assessing the degree of gland formation within histology images. To do this, it is important to consider the overall tissue micro-environment by assessing the cell-level…

图像与视频处理 · 电气工程与系统科学 2019-09-04 Yanning Zhou , Simon Graham , Navid Alemi Koohbanani , Muhammad Shaban , Pheng-Ann Heng , Nasir Rajpoot

With the remarkable success of representation learning for prediction problems, we have witnessed a rapid expansion of the use of machine learning and deep learning for the analysis of digital pathology and biopsy image patches. However,…

机器学习 · 计算机科学 2024-03-06 David Ahmedt-Aristizabal , Mohammad Ali Armin , Simon Denman , Clinton Fookes , Lars Petersson

Weakly-supervised classification of histopathology slides is a computationally intensive task, with a typical whole slide image (WSI) containing billions of pixels to process. We propose Discriminative Region Active Sampling for Multiple…

图像与视频处理 · 电气工程与系统科学 2023-02-23 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

Explainable AI (XAI) in medical histopathology is essential for enhancing the interpretability and clinical trustworthiness of deep learning models in cancer diagnosis. However, the black-box nature of these models often limits their…

图像与视频处理 · 电气工程与系统科学 2025-05-06 Raktim Kumar Mondol , Ewan K. A. Millar , Peter H. Graham , Lois Browne , Arcot Sowmya , Erik Meijering

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

图像与视频处理 · 电气工程与系统科学 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Deep models based on vision transformer (ViT) and convolutional neural network (CNN) have demonstrated remarkable performance on natural datasets. However, these models may not be similar in medical imaging, where abnormal regions cover…

计算机视觉与模式识别 · 计算机科学 2026-02-11 Ahmad Chaddad , Yihang Wu , Xianrui Chen

For many patients, current ovarian cancer treatments offer limited clinical benefit. For some therapies, it is not possible to predict patients' responses, potentially exposing them to the adverse effects of treatment without any…

图像与视频处理 · 电气工程与系统科学 2023-10-20 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nishant Ravikumar , Nicolas M. Orsi

Correct treatment of urothelial carcinoma patients is dependent on accurate grading and staging of the cancer tumour. This is determined manually by a pathologist by examining the histological whole-slide images (WSI). The large size of…

图像与视频处理 · 电气工程与系统科学 2019-09-12 Rune Wetteland , Kjersti Engan , Trygve Eftestøl , Vebjørn Kvikstad , Emilius A. M. Janssen

Ovarian cancer remains a challenging malignancy to diagnose and manage, with prognosis heavily dependent on the stage at detection. Accurate grading and staging, primarily based on histopathological examination of biopsy tissue samples, are…

医学物理 · 物理学 2025-05-16 Ashmit K Mishra , Mousa Alrubayan , Prabhakar Pradhan

Representation learning for Whole Slide Images (WSIs) is pivotal in developing image-based systems to achieve higher precision in diagnostic pathology. We propose a two-stage framework for WSI representation learning. We sample relevant…

图像与视频处理 · 电气工程与系统科学 2020-04-20 Mohammed Adnan , Shivam Kalra , Hamid R. Tizhoosh
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