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Alzheimer's disease (AD) is a neurodegenerative disorder with no known cure that affects tens of millions of people worldwide. Early detection of AD is critical for timely intervention to halt or slow the progression of the disease. In this…

机器学习 · 计算机科学 2025-07-08 Mahdi Moghaddami , Clayton Schubring , Mohammad-Reza Siadat

Alzheimer's disease (AD) is an irreversible, progressive neuro degenerative disorder that slowly destroys memory and thinking skills and eventually, the ability to carry out the simplest tasks. In this paper, a deep neural network based…

图像与视频处理 · 电气工程与系统科学 2021-05-17 Manu Subramoniam , Aparna T. R. , Anurenjan P. R. , Sreeni K. G

The aging population of the U.S. drives the prevalence of Alzheimer's disease. Brookmeyer et al. forecasts approximately 15 million Americans will have either clinical AD or mild cognitive impairment by 2060. In response to this urgent…

图像与视频处理 · 电气工程与系统科学 2023-12-01 Long Chen , Liben Chen , Binfeng Xu , Wenxin Zhang , Narges Razavian

In this study, we employ a transformer encoder model to characterize the significance of longitudinal patient data for forecasting the progression of Alzheimer's Disease (AD). Our model, Longitudinal Forecasting Model for Alzheimer's…

机器学习 · 计算机科学 2024-05-28 Batuhan K. Karaman , Mert R. Sabuncu

Automated methods for Alzheimer's disease (AD) classification have the potential for great clinical benefits and may provide insight for combating the disease. Machine learning, and more specifically deep neural networks, have been shown to…

The integration of multimodal medical imaging can provide complementary and comprehensive information for the diagnosis of Alzheimer's disease (AD). However, in clinical practice, since positron emission tomography (PET) is often missing,…

计算工程、金融与科学 · 计算机科学 2024-12-03 Fuyou Mao , Lixin Lin , Ming Jiang , Dong Dai , Chao Yang , Hao Zhang , Yan Tang

Alzheimer's Disease (AD) detection employs machine learning classification models to distinguish between individuals with AD and those without. Different from conventional classification tasks, we identify within-class variation as a…

音频与语音处理 · 电气工程与系统科学 2025-09-29 Jiawen Kang , Dongrui Han , Lingwei Meng , Jingyan Zhou , Jinchao Li , Xixin Wu , Helen Meng

Cross-modal fusion of different types of neuroimaging data has shown great promise for predicting the progression of Alzheimer's Disease(AD). However, most existing methods applied in neuroimaging can not efficiently fuse the functional and…

图像与视频处理 · 电气工程与系统科学 2022-07-15 Junren Pan , Shuqiang Wang

Alzheimer's Disease (AD) is a neurodegenerative disease that affects subjects in a broad range of severity and is assessed in clinical trials with multiple cognitive and functional instruments. As clinical trials in AD increasingly focus on…

We introduce AiM, an autoregressive (AR) image generative model based on Mamba architecture. AiM employs Mamba, a novel state-space model characterized by its exceptional performance for long-sequence modeling with linear time complexity,…

计算机视觉与模式识别 · 计算机科学 2025-11-04 Haopeng Li , Jinyue Yang , Kexin Wang , Xuerui Qiu , Yuhong Chou , Xin Li , Guoqi Li

Mild cognitive impairment (MCI) conversion prediction, i.e., identifying MCI patients of high risks converting to Alzheimer's disease (AD), is essential for preventing or slowing the progression of AD. Although previous studies have shown…

图像与视频处理 · 电气工程与系统科学 2021-09-27 Hao Guan , Chaoyue Wang , Dacheng Tao

Alzheimer's disease (AD) constitutes a neurodegenerative disease with serious consequences to peoples' everyday lives, if it is not diagnosed early since there is no available cure. Alzheimer's is the most common cause of dementia, which…

计算与语言 · 计算机科学 2023-01-18 Loukas Ilias , Dimitris Askounis , John Psarras

Modelling disease progression in precision medicine requires capturing complex spatio-temporal dynamics while preserving anatomical integrity. Existing methods often struggle with longitudinal dependencies and structural consistency in…

计算机视觉与模式识别 · 计算机科学 2025-05-16 Hao Yang , Tao Tan , Shuai Tan , Weiqin Yang , Kunyan Cai , Calvin Chen , Yue Sun

Alzheimer's disease (AD) is the most common cause of dementia. An early detection is crucial for slowing down the disease and mitigating risks related to the progression. While the combination of MRI and FDG-PET is the best image-based tool…

图像与视频处理 · 电气工程与系统科学 2022-06-17 Marcel Kollovieh , Matthias Keicher , Stephan Wunderlich , Hendrik Burwinkel , Thomas Wendler , Nassir Navab

Dementia, a prevalent neurodegenerative condition, is a major manifestation of Alzheimer's disease (AD). As the condition progresses from mild to severe, it significantly impairs the individual's ability to perform daily tasks…

机器学习 · 计算机科学 2023-11-06 Md Gulzar Hussain , Ye Shiren

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that severely impairs cognitive function and quality of life. Timely intervention in AD relies heavily on early and precise diagnosis, which remains challenging due to the…

计算机视觉与模式识别 · 计算机科学 2025-08-11 Xiaoxiao Yang , Meiliang Liu , Yunfang Xu , Zijin Li , Zhengye Si , Xinyue Yang , Zhiwen Zhao

Accurate detection of cardiac abnormalities from electrocardiogram recordings is regarded as essential for clinical diagnostics and decision support. Traditional deep learning models such as residual networks and transformer architectures…

计算机视觉与模式识别 · 计算机科学 2026-03-27 Huawei Jiang , Husna Mutahira , Gan Huang , Mannan Saeed Muhammad

Alzheimer's disease is one of the most common types of neurodegenerative disease, characterized by the accumulation of amyloid-beta plaque and tau tangles. Recently, deep learning approaches have shown promise in Alzheimer's disease…

图像与视频处理 · 电气工程与系统科学 2024-07-03 Gia Minh Hoang , Youngjoo Lee , Jae Gwan Kim

Introduction: Alzheimer's disease is a type of dementia in which early diagnosis plays a major rule in the quality of treatment. Among new works in the diagnosis of Alzheimer's disease, there are many of them analyzing the voice stream…

机器学习 · 计算机科学 2019-10-02 S. Soroush Haj Zargarbashi , Bagher Babaali

Longitudinal assessment of brain atrophy, particularly in the hippocampus, is a well-studied biomarker for neurodegenerative diseases, such as Alzheimer's disease (AD). In clinical trials, estimation of brain progressive rates can be…