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相关论文: Normative Diffusion Autoencoders: Application to A…

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Autoregressive models are ubiquitous tools for the analysis of time series in many domains such as computational neuroscience and biomedical engineering. In these domains, data is, for example, collected from measurements of brain activity.…

信号处理 · 电气工程与系统科学 2023-05-02 Jonas F. Haderlein , Andre D. H. Peterson , Anthony N. Burkitt , Iven M. Y. Mareels , David B. Grayden

Generative adversarial networks (GANs) are one powerful type of deep learning models that have been successfully utilized in numerous fields. They belong to a broader family called generative methods, which generate new data with a…

Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome characterized by cognitive impairment severe enough to interfere with activities of daily life. We aimed to conduct a systematic literature review (SLR) of…

定量方法 · 定量生物学 2021-08-31 Sayantan Kumar , Inez Oh , Suzanne Schindler , Albert M Lai , Philip R O Payne , Aditi Gupta

Accurate prediction of clinical scores is critical for early detection and prognosis of Alzheimers disease (AD). While existing approaches primarily focus on forecasting the ADAS-Cog global score, they often overlook the predictive value of…

Purpose : Because functional MRI (fMRI) data sets are in general small, we sought a data efficient approach to resting state fMRI classification of autism spectrum disorder (ASD) versus neurotypical (NT) controls. We hypothesized that a…

神经元与认知 · 定量生物学 2022-06-23 Joseph Stember , Danielle Stember , Luca Pasquini , Jenabi Merhnaz , Andrei Holodny , Hrithwik Shalu

Diffusion generative models have emerged as a powerful framework for addressing problems in structural biology and structure-based drug design. These models operate directly on 3D molecular structures. Due to the unfavorable scaling of…

生物大分子 · 定量生物学 2024-05-10 Ian Dunn , David Ryan Koes

Leveraging multimodal data, particularly the integration of whole-slide histology images (WSIs) and transcriptomic profiles, holds great promise for improving cancer survival prediction. However, excessive redundancy in multimodal data can…

图像与视频处理 · 电气工程与系统科学 2025-03-07 Hong Liu , Haosen Yang , Federica Eduati , Josien P. W. Pluim , Mitko Veta

This survey paper provides a comprehensive review of the use of diffusion models in natural language processing (NLP). Diffusion models are a class of mathematical models that aim to capture the diffusion of information or signals across a…

计算与语言 · 计算机科学 2023-06-16 Hao Zou , Zae Myung Kim , Dongyeop Kang

Deep learning has been successful in predicting neurodegenerative disorders, such as Alzheimer's disease, from magnetic resonance imaging (MRI). Combining multiple imaging modalities, such as T1-weighted (T1) and diffusion-weighted imaging…

Magnetic resonance imaging (MRI) is a powerful medical imaging modality, but long acquisition times limit throughput, patient comfort, and clinical accessibility. Diffusion-based generative models serve as strong image priors for reducing…

机器学习 · 计算机科学 2026-02-13 Sriram Ravula , Brett Levac , Yamin Arefeen , Ajil Jalal , Alexandros G. Dimakis , Jonathan I. Tamir

With the emergence of diffusion models as a frontline generative model, many researchers have proposed molecule generation techniques with conditional diffusion models. However, the unavoidable discreteness of a molecule makes it difficult…

机器学习 · 计算机科学 2025-06-05 Jinho Chang , Jong Chul Ye

Early diagnosis and intervention for Autism Spectrum Disorder (ASD) has been shown to significantly improve the quality of life of autistic individuals. However, diagnostics methods for ASD rely on assessments based on clinical presentation…

图像与视频处理 · 电气工程与系统科学 2025-03-05 Suryansh Vidya , Kush Gupta , Amir Aly , Andy Wills , Emmanuel Ifeachor , Rohit Shankar

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

计算机视觉与模式识别 · 计算机科学 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

Early prediction of Mild Cognitive Impairment (MCI) conversion is hampered by a trade-off between immediacy--making fast predictions from a single baseline sMRI--and accuracy--leveraging longitudinal scans to capture disease progression. We…

机器学习 · 计算机科学 2025-06-09 Zhihao Tang , Chaozhuo Li , Litian Zhang , Xi Zhang

Stroke is a common disabling neurological condition that affects about one-quarter of the adult population over age 25; more than half of patients still have poor outcomes, such as permanent functional dependence or even death, after the…

计算机视觉与模式识别 · 计算机科学 2024-02-19 Chia-Ling Tsai , Hui-Yun Su , Shen-Feng Sung , Wei-Yang Lin , Ying-Ying Su , Tzu-Hsien Yang , Man-Lin Mai

Deep learning (DL) for predicting Alzheimer's disease (AD) has provided timely intervention in disease progression yet still demands attentive interpretability to explain how their DL models make definitive decisions. Recently,…

人工智能 · 计算机科学 2023-10-06 Kwanseok Oh , Da-Woon Heo , Ahmad Wisnu Mulyadi , Wonsik Jung , Eunsong Kang , Kun Ho Lee , Heung-Il Suk

An important feature of successful supervised machine learning applications is to be able to explain the predictions given by the regression or classification model being used. However, most state-of-the-art models that have good predictive…

Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease…

计算机视觉与模式识别 · 计算机科学 2025-11-27 Xin Honga , Jie Lin , Minghui Wang

The scarcity of high-quality segmentation masks remains a major bottleneck for medical image analysis, particularly in non-contrast CT (NCCT) neuroimaging, where manual annotation is costly and variable. To address this limitation, we…

图像与视频处理 · 电气工程与系统科学 2026-02-12 Lucia Borrego , Vajira Thambawita , Marco Ciuffreda , Ines del Val , Alejandro Dominguez , Josep Munuera

Active Learning (AL) is increasingly important in a broad range of applications. Two main AL principles to obtain accurate classification with few labeled data are refinement of the current decision boundary and exploration of poorly…

机器学习 · 计算机科学 2012-10-19 Jens Roeder , Boaz Nadler , Kevin Kunzmann , Fred A. Hamprecht