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The detection of nuclei is one of the most fundamental components of computational pathology. Current state-of-the-art methods are based on deep learning, with the prerequisite that extensive labeled datasets are available. The increasing…

图像与视频处理 · 电气工程与系统科学 2019-07-11 Nicolas Brieu , Armin Meier , Ansh Kapil , Ralf Schoenmeyer , Christos G. Gavriel , Peter D. Caie , Günter Schmidt

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

计算机视觉与模式识别 · 计算机科学 2025-08-05 Anwai Archit , Constantin Pape

Unsupervised domain adaptation (UDA) methods have been broadly utilized to improve the models' adaptation ability in general computer vision. However, different from the natural images, there exist huge semantic gaps for the nuclei from…

计算机视觉与模式识别 · 计算机科学 2022-07-05 Canran Li , Dongnan Liu , Haoran Li , Zheng Zhang , Guangming Lu , Xiaojun Chang , Weidong Cai

The limited ability of Convolutional Neural Networks to generalize to images from previously unseen domains is a major limitation, in particular, for safety-critical clinical tasks such as dermoscopic skin cancer classification. In order to…

计算机视觉与模式识别 · 计算机科学 2023-07-04 Katharina Fogelberg , Sireesha Chamarthi , Roman C. Maron , Julia Niebling , Titus J. Brinker

In the cancer diagnosis pipeline, digital pathology plays an instrumental role in the identification, staging, and grading of malignant areas on biopsy tissue specimens. High resolution histology images are subject to high variance in…

图像与视频处理 · 电气工程与系统科学 2023-08-17 Vasileios Magoulianitis , Catherine A. Alexander , C. -C. Jay Kuo

Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…

机器学习 · 计算机科学 2026-03-18 Camille Jimenez Cortes , Philippe Lalanda , German Vega

End-to-end deep learning improves breast cancer classification on diffusion-weighted MR images (DWI) using a convolutional neural network (CNN) architecture. A limitation of CNN as opposed to previous model-based approaches is the…

Convolutional neural networks (CNNs) have led to significant improvements in the semantic segmentation of images. When source and target datasets come from different modalities, CNN performance suffers due to domain shift. In such cases…

计算机视觉与模式识别 · 计算机科学 2022-10-10 Serban Stan , Mohammad Rostami

Annotation scarcity and cross-modality/stain data distribution shifts are two major obstacles hindering the application of deep learning models for nuclei analysis, which holds a broad spectrum of potential applications in digital…

计算机视觉与模式识别 · 计算机科学 2024-01-23 Jianan Fan , Dongnan Liu , Hang Chang , Weidong Cai

Time series anomaly detection is a challenging task with a wide range of real-world applications. Due to label sparsity, training a deep anomaly detector often relies on unsupervised approaches. Recent efforts have been devoted to time…

机器学习 · 计算机科学 2023-04-18 Kwei-Herng Lai , Lan Wang , Huiyuan Chen , Kaixiong Zhou , Fei Wang , Hao Yang , Xia Hu

Correspondence-based shape models are key to various medical imaging applications that rely on a statistical analysis of anatomies. Such shape models are expected to represent consistent anatomical features across the population for…

计算机视觉与模式识别 · 计算机科学 2021-02-23 Praful Agrawal , Ross T. Whitaker , Shireen Y. Elhabian

Deep learning models for dermatological image analysis remain sensitive to acquisition variability and domain-specific visual characteristics, leading to performance degradation when deployed in clinical settings. We investigate how visual…

计算机视觉与模式识别 · 计算机科学 2026-02-24 Rodrigo Mota , Kelvin Cunha , Emanoel dos Santos , Fábio Papais , Francisco Filho , Thales Bezerra , Erico Medeiros , Paulo Borba , Tsang Ing Ren

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

计算机视觉与模式识别 · 计算机科学 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Most prior unsupervised domain adaptation approaches for medical image segmentation are narrowly tailored to either the source-accessible setting, where adaptation is guided by source-target alignment, or the source-free setting, which…

计算机视觉与模式识别 · 计算机科学 2026-03-10 Xin Wang , Yin Guo , Jiamin Xia , Kaiyu Zhang , Niranjan Balu , Mahmud Mossa-Basha , Linda Shapiro , Chun Yuan

In real-world visual recognition problems, the assumption that the training data (source domain) and test data (target domain) are sampled from the same distribution is often violated. This is known as the domain adaptation problem. In this…

计算机视觉与模式识别 · 计算机科学 2018-04-17 Hongyu Xu , Jingjing Zheng , Azadeh Alavi , Rama Chellappa

Domain adaptation for semantic segmentation aims to improve the model performance in the presence of a distribution shift between source and target domain. Leveraging the supervision from auxiliary tasks~(such as depth estimation) has the…

计算机视觉与模式识别 · 计算机科学 2021-08-25 Qin Wang , Dengxin Dai , Lukas Hoyer , Luc Van Gool , Olga Fink

Current state-of-the-art visual recognition systems usually rely on the following pipeline: (a) pretraining a neural network on a large-scale dataset (e.g., ImageNet) and (b) finetuning the network weights on a smaller, task-specific…

计算机视觉与模式识别 · 计算机科学 2021-04-01 Guangrun Wang , Liang Lin , Rongcong Chen , Guangcong Wang , Jiqi Zhang

Accurate segmentation of tissue in histopathological images can be very beneficial for defining regions of interest (ROI) for streamline of diagnostic and prognostic tasks. Still, adapting to different domains is essential for…

图像与视频处理 · 电气工程与系统科学 2023-03-10 Saul Fuster , Farbod Khoraminia , Trygve Eftestøl , Tahlita C. M. Zuiverloon , Kjersti Engan

Neural circuits are able to perform computations under very diverse conditions and requirements. The required computations impose clear constraints on their fine-tuning: a rapid and maximally informative response to stimuli in general…

Automated cellular instance segmentation is a process utilized for accelerating biological research for the past two decades, and recent advancements have produced higher quality results with less effort from the biologist. Most current…

计算机视觉与模式识别 · 计算机科学 2023-01-02 Matthew Keaton , Ram Zaveri , Gianfranco Doretto
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