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One of the main obstacles of adopting digital pathology is the challenge of efficient processing of hyperdimensional digitized biopsy samples, called whole slide images (WSIs). Exploiting deep learning and introducing compact WSI…

计算机视觉与模式识别 · 计算机科学 2023-04-19 Azam Asilian Bidgoli , Shahryar Rahnamayan , Taher Dehkharghanian , Abtin Riasatian , H. R. Tizhoosh

Prompt-based fine-tuning for pre-trained models has proven effective for many natural language processing tasks under few-shot settings in general domain. However, tuning with prompt in biomedical domain has not been investigated…

计算与语言 · 计算机科学 2023-04-17 Haochun Wang , Chi Liu , Nuwa Xi , Sendong Zhao , Meizhi Ju , Shiwei Zhang , Ziheng Zhang , Yefeng Zheng , Bing Qin , Ting Liu

In computational pathology, weak supervision has become the standard for deep learning due to the gigapixel scale of WSIs and the scarcity of pixel-level annotations, with Multiple Instance Learning (MIL) established as the principal…

计算机视觉与模式识别 · 计算机科学 2025-12-17 Andreas Lolos , Theofilos Christodoulou , Aris L. Moustakas , Stergios Christodoulidis , Maria Vakalopoulou

Few-shot classification is a challenging task which aims to formulate the ability of humans to learn concepts from limited prior data and has drawn considerable attention in machine learning. Recent progress in few-shot classification has…

机器学习 · 计算机科学 2020-04-14 Meiyu Huang , Xueshuang Xiang , Yao Xu

Clinical note classification is a common clinical NLP task. However, annotated data-sets are scarse. Prompt-based learning has recently emerged as an effective method to adapt pre-trained models for text classification using only few…

计算与语言 · 计算机科学 2023-11-01 Eugenia Alleva , Isotta Landi , Leslee J Shaw , Erwin Böttinger , Thomas J Fuchs , Ipek Ensari

Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…

图像与视频处理 · 电气工程与系统科学 2024-11-22 Manahil Raza , Ruqayya Awan , Raja Muhammad Saad Bashir , Talha Qaiser , Nasir M. Rajpoot

Image recognition has recently witnessed a paradigm shift, where vision-language models are now used to perform few-shot classification based on textual prompts. Among these, the CLIP model has shown remarkable capabilities for zero-shot…

计算机视觉与模式识别 · 计算机科学 2023-07-27 Lorenzo Agnolucci , Alberto Baldrati , Francesco Todino , Federico Becattini , Marco Bertini , Alberto Del Bimbo

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

图像与视频处理 · 电气工程与系统科学 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Foundation models such as the recently introduced Segment Anything Model (SAM) have achieved remarkable results in image segmentation tasks. However, these models typically require user interaction through handcrafted prompts such as…

计算机视觉与模式识别 · 计算机科学 2024-10-01 Mélanie Gaillochet , Christian Desrosiers , Hervé Lombaert

Gigapixel image analysis, particularly for whole slide images (WSIs), often relies on multiple instance learning (MIL). Under the paradigm of MIL, patch image representations are extracted and then fixed during the training of the MIL…

计算机视觉与模式识别 · 计算机科学 2024-12-20 Kunming Tang , Zhiguo Jiang , Jun Shi , Wei Wang , Haibo Wu , Yushan Zheng

In pre-clinical pathology, there is a paradox between the abundance of raw data (whole slide images from many organs of many individual animals) and the lack of pixel-level slide annotations done by pathologists. Due to time constraints and…

计算机视觉与模式识别 · 计算机科学 2023-02-06 Marco Bertolini , Van-Khoa Le , Jake Pencharz , Andreas Poehlmann , Djork-Arné Clevert , Santiago Villalba , Floriane Montanari

Deep learning offers transformative potential in medical imaging, yet its clinical adoption is frequently hampered by challenges such as data scarcity, distribution shifts, and the need for robust task generalization. Prompt-based…

图像与视频处理 · 电气工程与系统科学 2025-07-03 Hao Yang , Xinlong Liang , Zhang Li , Yue Sun , Zheyu Hu , Xinghe Xie , Behdad Dashtbozorg , Jincheng Huang , Shiwei Zhu , Luyi Han , Jiong Zhang , Shanshan Wang , Ritse Mann , Qifeng Yu , Tao Tan

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

计算机视觉与模式识别 · 计算机科学 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

Few-shot classification consists of learning a predictive model that is able to effectively adapt to a new class, given only a few annotated samples. To solve this challenging problem, meta-learning has become a popular paradigm that…

计算机视觉与模式识别 · 计算机科学 2019-09-02 Nikita Dvornik , Cordelia Schmid , Julien Mairal

Computational pathology has advanced rapidly in recent years, driven by domain-specific image encoders and growing interest in using vision-language models to answer natural-language questions about diseases. Yet, the core problem behind…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Wentao Huang , Weimin Lyu , Peiliang Lou , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Wenchao Han , Ruifeng Guo , Jiawei Zhou , Chao Chen , Chen Wang

Multiple Instance Learning (MIL) for whole slide image (WSI) analysis in computational pathology often neglects instance-level learning as supervision is typically provided only at the bag level, hindering the integrated consideration of…

In the last decades, large datasets of fundus photographs have been collected in diabetic retinopathy (DR) screening networks. Through deep learning, these datasets were used to train automatic detectors for DR and a few other frequent…

计算机视觉与模式识别 · 计算机科学 2020-02-11 Gwenolé Quellec , Mathieu Lamard , Pierre-Henri Conze , Pascale Massin , Béatrice Cochener

Traditional whole slide image (WSI) analysis methods typically rely on the multiple instance learning (MIL) paradigm, which extracts patch-level features at high magnification and aggregates them for slide-level prediction. However, such…

We present a novel weakly-supervised framework for classifying whole slide images (WSIs). WSIs, due to their gigapixel resolution, are commonly processed by patch-wise classification with patch-level labels. However, patch-level labels…

计算机视觉与模式识别 · 计算机科学 2022-03-10 Tiange Xiang , Yang Song , Chaoyi Zhang , Dongnan Liu , Mei Chen , Fan Zhang , Heng Huang , Lauren O'Donnell , Weidong Cai

Whole slide images (WSIs) in computational pathology (CPath) pose a major computational challenge due to their gigapixel scale, often requiring the processing of tens to hundreds of thousands of high-resolution patches per slide. This…

计算机视觉与模式识别 · 计算机科学 2025-08-21 Yonghan Shin , SeungKyu Kim , Won-Ki Jeong