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Accurate diagnosis of pediatric brain tumors, starting with histopathology, presents unique challenges for deep learning, including severe data scarcity, class imbalance, and fine-grained morphologic overlap across diagnostically distinct…

计算机视觉与模式识别 · 计算机科学 2026-05-21 Joakim Nguyen , Jian Yu , Jinrui Fang , Nicholas Konz , Tianlong Chen , Sanjay Krishnan , Chandra Krishnan , Ying Ding , Hairong Wang , Ankita Shukla

Recent advances in whole slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence (AI) based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath)…

Recent Vision-Language Pretrained (VLP) models have become the backbone for many downstream tasks, but they are utilized as frozen model without learning. Prompt learning is a method to improve the pre-trained VLP model by adding a…

计算与语言 · 计算机科学 2024-01-17 Youngjae Cho , HeeSun Bae , Seungjae Shin , Yeo Dong Youn , Weonyoung Joo , Il-Chul Moon

Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…

计算机视觉与模式识别 · 计算机科学 2024-05-21 Andrew H. Song , Richard J. Chen , Tong Ding , Drew F. K. Williamson , Guillaume Jaume , Faisal Mahmood

Current cervical cytopathology whole slide image (WSI) screening primarily relies on detection-based approaches, which are limited in performance due to the expense and time-consuming annotation process. Multiple Instance Learning (MIL), a…

计算机视觉与模式识别 · 计算机科学 2024-07-17 Jialong Huang , Gaojie Li , Shichao Kan , Jianfeng Liu , Yixiong Liang

Whole Slide Images (WSIs) exhibit hierarchical structure, where diagnostic information emerges from cellular morphology, regional tissue organization, and global context. Existing Computational Pathology (CPath) Multimodal Large Language…

Multiple instance learning (MIL) has been successfully applied for whole slide images (WSIs) analysis in computational pathology, enabling a wide range of prediction tasks from tumor subtyping to inferring genetic mutations and multi-omics…

计算机视觉与模式识别 · 计算机科学 2024-07-25 Junyu Li , Ye Zhang , Wen Shu , Xiaobing Feng , Yingchun Wang , Pengju Yan , Xiaolin Li , Chulin Sha , Min He

Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images…

计算机视觉与模式识别 · 计算机科学 2025-11-20 Xiangde Luo , Jinxi Xiang , Yuanfeng Ji , Ruijiang Li

Multiple Instance Learning (MIL) methods have succeeded remarkably in histopathology whole slide image (WSI) analysis. However, most MIL models only offer attention-based explanations that do not faithfully capture the model's decision…

计算机视觉与模式识别 · 计算机科学 2025-07-17 Susu Sun , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer diagnosis. Limited by the expensive cost of pixel-level…

计算机视觉与模式识别 · 计算机科学 2024-11-19 Jiawen Li , Qiehe Sun , Renao Yan , Yizhi Wang , Yuqiu Fu , Yani Wei , Tian Guan , Huijuan Shi , Yonghonghe He , Anjia Han

Prompt learning is a new learning paradigm which reformulates downstream tasks as similar pretraining tasks on pretrained models by leveraging textual prompts. Recent works have demonstrated that prompt learning is particularly useful for…

计算与语言 · 计算机科学 2022-10-21 Yue Zhang , Hongliang Fei , Dingcheng Li , Tan Yu , Ping Li

Prompt-based fine-tuning has boosted the performance of Pre-trained Language Models (PLMs) on few-shot text classification by employing task-specific prompts. Yet, PLMs are unfamiliar with prompt-style expressions during pre-training, which…

计算与语言 · 计算机科学 2022-05-12 Jianing Wang , Chengyu Wang , Fuli Luo , Chuanqi Tan , Minghui Qiu , Fei Yang , Qiuhui Shi , Songfang Huang , Ming Gao

The lack of annotated medical images limits the performance of deep learning models, which usually need large-scale labelled datasets. Few-shot learning techniques can reduce data scarcity issues and enhance medical image analysis,…

计算机视觉与模式识别 · 计算机科学 2024-06-25 Eva Pachetti , Sara Colantonio

Pathological diagnosis is vital for determining disease characteristics, guiding treatment, and assessing prognosis, relying heavily on detailed, multi-scale analysis of high-resolution whole slide images (WSI). However, existing large…

计算机视觉与模式识别 · 计算机科学 2025-05-19 Shengxuming Zhang , Weihan Li , Tianhong Gao , Jiacong Hu , Haoming Luo , Xiuming Zhang , Jing Zhang , Mingli Song , Zunlei Feng

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

计算机视觉与模式识别 · 计算机科学 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King

Leveraging pre-trained models with tailored prompts for in-context learning has proven highly effective in NLP tasks. Building on this success, recent studies have applied a similar approach to the Segment Anything Model (SAM) within a…

计算机视觉与模式识别 · 计算机科学 2024-11-26 Hangyul Yoon , Doohyuk Jang , Jungeun Kim , Eunho Yang

Cancer survival prediction is a challenging task that involves analyzing of the tumor microenvironment within Whole Slide Image (WSI). Previous methods cannot effectively capture the intricate interaction features among instances within the…

计算机视觉与模式识别 · 计算机科学 2024-10-23 Zekang Yang , Hong Liu , Xiangdong Wang

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Pre-trained Vision-Language Models (VLMs), like CLIP, exhibit strong generalization ability to downstream tasks but struggle in few-shot scenarios. Existing prompting techniques primarily focus on global text and image representations, yet…

计算机视觉与模式识别 · 计算机科学 2024-07-12 Xin Liu , Jiamin Wu , and Wenfei Yang , Xu Zhou , Tianzhu Zhang

Prompt learning has demonstrated impressive efficacy in the fine-tuning of multimodal large models to a wide range of downstream tasks. Nonetheless, applying existing prompt learning methods for the diagnosis of neurological disorder still…

计算机视觉与模式识别 · 计算机科学 2024-06-28 Liang Peng , Songyue Cai , Zongqian Wu , Huifang Shang , Xiaofeng Zhu , Xiaoxiao Li