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The prediction of protein 3D structure from amino acid sequence is a computational grand challenge in biophysics, and plays a key role in robust protein structure prediction algorithms, from drug discovery to genome interpretation. The…

生物大分子 · 定量生物学 2024-07-03 Hyun Park , Parth Patel , Roland Haas , E. A. Huerta

In the context of human-in-the-loop Machine Learning applications, like Decision Support Systems, interpretability approaches should provide actionable insights without making the users wait. In this paper, we propose Accelerated…

机器学习 · 计算机科学 2021-12-24 David Dandolo , Chiara Masiero , Mattia Carletti , Davide Dalle Pezze , Gian Antonio Susto

The availability of large data sets is providing an impetus for driving current artificial intelligent developments. There are, however, challenges for developing solutions with small data sets due to practical and cost-effective deployment…

机器学习 · 计算机科学 2024-05-17 Luca Gherardini , Varun Ravi Varma , Karol Capala , Roger Woods , Jose Sousa

Estimating covariance matrix from massive high-dimensional and distributed data is significant for various real-world applications. In this paper, we propose a data-aware weighted sampling based covariance matrix estimator, namely DACE,…

机器学习 · 计算机科学 2020-10-13 Xixian Chen , Haiqin Yang , Shenglin Zhao , Michael R. Lyu , Irwin King

Panic attacks are acute episodes of fear and distress, in which timely, appropriate intervention can significantly help individuals regain stability. However, suitable datasets for training such models remain scarce due to ethical and…

人工智能 · 计算机科学 2025-10-29 Jihyun Lee , Yejin Min , San Kim , Yejin Jeon , SungJun Yang , Hyounghun Kim , Gary Geunbae Lee

Optical Character Recognition (OCR) is an established task with the objective of identifying the text present in an image. While many off-the-shelf OCR models exist, they are often trained for either scientific (e.g., formulae) or generic…

计算与语言 · 计算机科学 2024-03-26 Nan Zhang , Connor Heaton , Sean Timothy Okonsky , Prasenjit Mitra , Hilal Ezgi Toraman

In this paper, we propose a novel system that integrates state-of-the-art, domain-specific large language models with advanced information retrieval techniques to deliver comprehensive and context-aware responses. Our approach facilitates…

Keeping track of scientific challenges, advances and emerging directions is a fundamental part of research. However, researchers face a flood of papers that hinders discovery of important knowledge. In biomedicine, this directly impacts…

This paper introduces a generalized ps-BART model for the estimation of Average Treatment Effect (ATE) and Conditional Average Treatment Effect (CATE) in continuous treatments, addressing limitations of the Bayesian Causal Forest (BCF)…

机器学习 · 统计学 2024-09-11 Hugo Gobato Souto , Francisco Louzada Neto

In robotics, diffusion models can capture multi-modal trajectories from demonstrations, making them a transformative approach in imitation learning. However, achieving optimal performance following this regiment requires a large-scale…

The AUTO-PCOS Classification Challenge seeks to advance the diagnostic capabilities of artificial intelligence (AI) in identifying Polycystic Ovary Syndrome (PCOS) through automated classification of healthy and unhealthy ultrasound frames.…

图像与视频处理 · 电气工程与系统科学 2025-01-07 Atharva Divekar , Atharva Sonawane

Cardinality estimation (CE) plays a crucial role in many database-related tasks such as query generation, cost estimation, and join ordering. Lately, we have witnessed the emergence of numerous learned CE models. However, no single CE model…

数据库 · 计算机科学 2024-09-25 Jintao Zhang , Chao Zhang , Guoliang Li , Chengliang Chai

Pathological assessment guides lung cancer diagnosis, treatment selection, and prognostic evaluation, yet current CPath approaches rely on task-specific models for isolated objectives. Although pan-cancer foundation models offer…

Multimodal data provides heterogeneous information for a holistic understanding of the tumor microenvironment. However, existing AI models often struggle to harness the rich information within multimodal data and extract poorly…

机器学习 · 计算机科学 2025-09-17 Huajun Zhou , Fengtao Zhou , Jiabo Ma , Yingxue Xu , Xi Wang , Xiuming Zhang , Li Liang , Zhenhui Li , Hao Chen

Cardiac image analysis remains fragmented across tasks: anatomical segmentation, disease classification, and grounded clinical report generation are typically handled by separate networks trained under different data regimes. No existing…

计算机视觉与模式识别 · 计算机科学 2025-12-04 Hania Ghouse , Maryam Alsharqi , Farhad R. Nezami , Muzammil Behzad

Accurate phase estimation at the edge of data segments is crucial for EEG applications such as EEG-TMS in offline and real-time data analysis. Our research evaluates the phase estimation performance of four commonly used methods…

神经元与认知 · 定量生物学 2026-04-03 Miriam Kirchhoff , Johanna Rösch , Maria Ermolova , Oskari Ahola , Sarah Harders , Juliana Hougland , Ulf Ziemann

Clinical value set authoring -- the task of identifying all codes in a standardized vocabulary that define a clinical concept -- is a recurring bottleneck in clinical quality measurement and phenotyping. A natural approach is to prompt a…

Active learning (AL) has the potential to drastically reduce annotation costs in 3D biomedical image segmentation, where expert labeling of volumetric data is both time-consuming and expensive. Yet, existing AL methods are unable to…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Carsten T. Lüth , Jeremias Traub , Kim-Celine Kahl , Till J. Bungert , Lukas Klein , Lars Krämer , Paul F. Jäger , Klaus Maier-Hein , Fabian Isensee

Causal relation extraction (CRE) is central to biomedical text mining, but current resources often conflate causal relations with broader associations, restrict annotation to sentence-level examples, or focus mainly on explicit causal cues.…

计算与语言 · 计算机科学 2026-05-28 Ifeoluwa Kunle-John , Josiah Paul , Oluwatosin Agbaakin , Peter Aina , Ikenna Odezuligbo , Sydney Anuyah

Sparse polynomial chaos expansions (PCE) are an efficient and widely used surrogate modeling method in uncertainty quantification for engineering problems with computationally expensive models. To make use of the available information in…

统计计算 · 统计学 2021-07-26 Nora Lüthen , Stefano Marelli , Bruno Sudret