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Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

图像与视频处理 · 电气工程与系统科学 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Histopathology remains the gold standard for diagnosis of various cancers. Recent advances in computer vision, specifically deep learning, have facilitated the analysis of histopathology images for various tasks, including immune cell…

定量方法 · 定量生物学 2023-11-02 Jakub R. Kaczmarzyk , Tahsin M. Kurc , Shahira Abousamra , Rajarsi Gupta , Joel H. Saltz , Peter K. Koo

Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and…

计算机视觉与模式识别 · 计算机科学 2025-05-29 Yuan Zhang , Feng Chen , Yaolei Qi , Guanyu Yang , Huazhu Fu

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

计算机视觉与模式识别 · 计算机科学 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

The complexity and variability inherent in high-resolution pathological images present significant challenges in computational pathology. While pathology foundation models leveraging AI have catalyzed transformative advancements, their…

Segmentation is a critical task in computational pathology, as it identifies areas affected by disease or abnormal growth and is essential for diagnosis and treatment. However, acquiring high-quality pixel-level supervised segmentation data…

计算机视觉与模式识别 · 计算机科学 2026-05-07 Zhiling Yan , Sicheng Chen , Tianyi Zhang , Nan Ying , Yanli Lei , Guanglei Zhang

We propose a CNN based technique that aggregates feature maps from its multiple layers that can localize abnormalities with greater details as well as predict pathology under consideration. Existing class activation mapping (CAM) techniques…

计算机视觉与模式识别 · 计算机科学 2019-10-01 Sumeet Shinde , Tanay Chougule , Jitender Saini , Madhura Ingalhalikar

Artificial Intelligence (AI) has great potential to improve health outcomes by training systems on vast digitized clinical datasets. Computational Pathology, with its massive amounts of microscopy image data and impact on diagnostics and…

图像与视频处理 · 电气工程与系统科学 2024-05-24 Gabriele Campanella , Eugene Fluder , Jennifer Zeng , Chad Vanderbilt , Thomas J. Fuchs

Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…

For a given causal question, it is important to efficiently decide which causal inference method to use for a given dataset. This is challenging because causal methods typically rely on complex and difficult-to-verify assumptions, and…

机器学习 · 计算机科学 2023-11-09 Shantanu Gupta , Cheng Zhang , Agrin Hilmkil

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

图像与视频处理 · 电气工程与系统科学 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

While high-resolution pathology images lend themselves well to `data hungry' deep learning algorithms, obtaining exhaustive annotations on these images is a major challenge. In this paper, we propose a self-supervised CNN approach to…

计算机视觉与模式识别 · 计算机科学 2020-08-14 Navid Alemi Koohbanani , Balagopal Unnikrishnan , Syed Ali Khurram , Pavitra Krishnaswamy , Nasir Rajpoot

In the last years, neural networks have proven to be a powerful framework for various image analysis problems. However, some application domains have specific limitations. Notably, digital pathology is an example of such fields due to…

计算机视觉与模式识别 · 计算机科学 2018-02-06 Gleb Makarchuk , Vladimir Kondratenko , Maxim Pisov , Artem Pimkin , Egor Krivov , Mikhail Belyaev

In this paper, we explore a novel image matting task aimed at achieving efficient inference under various computational cost constraints, specifically FLOP limitations, using a single matting network. Existing matting methods which have not…

计算机视觉与模式识别 · 计算机科学 2025-03-06 Qinglin Liu , Zonglin Li , Xiaoqian Lv , Xin Sun , Ru Li , Shengping Zhang

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

Weak supervision learning on classification labels has demonstrated high performance in various tasks, while a few pixel-level fine annotations are also affordable. Naturally a question comes to us that whether the combination of…

计算机视觉与模式识别 · 计算机科学 2021-10-26 Jiahui Li , Wen Chen , Xiaodi Huang , Zhiqiang Hu , Qi Duan , Hongsheng Li , Dimitris N. Metaxas , Shaoting Zhang

Text-image cross-modal retrieval is a challenging task in the field of language and vision. Most previous approaches independently embed images and sentences into a joint embedding space and compare their similarities. However, previous…

计算机视觉与模式识别 · 计算机科学 2019-09-13 Zihao Wang , Xihui Liu , Hongsheng Li , Lu Sheng , Junjie Yan , Xiaogang Wang , Jing Shao

Imaging in clinical routine is subject to changing scanner protocols, hardware, or policies in a typically heterogeneous set of acquisition hardware. Accuracy and reliability of deep learning models suffer from those changes as data and…

机器学习 · 计算机科学 2021-06-08 Matthias Perkonigg , Johannes Hofmanninger , Georg Langs

Multimodal pathological image understanding has garnered widespread interest due to its potential to improve diagnostic accuracy and enable personalized treatment through integrated visual and textual data. However, existing methods exhibit…

计算机视觉与模式识别 · 计算机科学 2025-05-22 Zhe Xu , Cheng Jin , Yihui Wang , Ziyi Liu , Hao Chen

Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood