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The rapid generation of whole-slide images (WSIs) in dermatopathology necessitates automated methods for efficient processing and accurate classification. This study evaluates the performance of two foundation models, UNI and Virchow2, as…

计算机视觉与模式识别 · 计算机科学 2025-10-27 Riya Gupta , Yiwei Zong , Dennis H. Murphree

Whole-slide image (WSI) analysis remains challenging due to the gigapixel scale and sparsely distributed diagnostic regions. Multiple Instance Learning (MIL) mitigates this by modeling the WSI as bags of patches for slide-level prediction.…

计算机视觉与模式识别 · 计算机科学 2025-08-05 Yujian Liu , Yuechuan Lin , Dongxu Shen , Haoran Li , Yutong Wang , Xiaoli Liu , Shidang Xu

Traditional image-based survival prediction models rely on discriminative patch labeling which make those methods not scalable to extend to large datasets. Recent studies have shown Multiple Instance Learning (MIL) framework is useful for…

图像与视频处理 · 电气工程与系统科学 2020-09-24 Jiawen Yao , Xinliang Zhu , Jitendra Jonnagaddala , Nicholas Hawkins , Junzhou Huang

Accurate analysis of histopathological images is critical for disease diagnosis and treatment planning. Whole-slide images (WSIs), which digitize tissue specimens at gigapixel resolution, are fundamental to this process but require…

计算机视觉与模式识别 · 计算机科学 2026-05-07 Enhui Chai , Sicheng Chen , Tianyi Zhang , Chad Wong , Kecheng Huang , Zeyu Liu , Fei Xia

Diagnosing diseases through histopathology whole slide images (WSIs) is fundamental in modern pathology but is challenged by the gigapixel scale and complexity of WSIs. Trained histopathologists overcome this challenge by navigating the…

Whole-slide image (WSI) multiple instance learning (MIL) classifiers can achieve strong slide-level AUC while leaving the full-bag prediction opaque. Attention scores are widely reused as post-hoc explanations, but high attention can…

图像与视频处理 · 电气工程与系统科学 2026-05-14 Hyun Do Jung , Jungwon Choi , Soojung Choi , Yujin Oh , Hwiyoung Kim

The fusion of LiDARs and cameras has been increasingly adopted in autonomous driving for perception tasks. The performance of such fusion-based algorithms largely depends on the accuracy of sensor calibration, which is challenging due to…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Yuxuan Xiao , Yao Li , Chengzhen Meng , Xingchen Li , Jianmin Ji , Yanyong Zhang

Digital pathology provides an excellent opportunity for applying fully convolutional networks (FCNs) to tasks, such as semantic segmentation of whole slide images (WSIs). However, standard FCNs face challenges with respect to…

计算机视觉与模式识别 · 计算机科学 2018-07-26 Feng Gu , Nikolay Burlutskiy , Mats Andersson , Lena Kajland Wilen

Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

计算机视觉与模式识别 · 计算机科学 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

计算机视觉与模式识别 · 计算机科学 2022-03-02 Richard J. Chen , Rahul G. Krishnan

Joint analysis of multiple biomarker images and tissue morphology is important for disease diagnosis, treatment planning and drug development. It requires cross-staining comparison among Whole Slide Images (WSIs) of immuno-histochemical and…

图像与视频处理 · 电气工程与系统科学 2022-07-05 Abubakr Shafique , Morteza Babaie , Mahjabin Sajadi , Adrian Batten , Soma Skdar , H. R. Tizhoosh

Supervised deep learning methods have achieved considerable success in medical image analysis, owing to the availability of large-scale and well-annotated datasets. However, creating such datasets for whole slide images (WSIs) in…

计算机视觉与模式识别 · 计算机科学 2024-06-10 Hao Wang , Euijoon Ahn , Jinman Kim

Recent Transformer-based low-light enhancement methods have made promising progress in recovering global illumination. However, they still struggle with non-uniform lighting scenarios, such as backlit and shadow, appearing as over-exposure…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Hanting Li , Fei Zhou , Xin Sun , Yang Hua , Jungong Han , Liang-Jie Zhang

As the core building block of vision transformers, attention is a powerful tool to capture long-range dependency. However, such power comes at a cost: it incurs a huge computation burden and heavy memory footprint as pairwise token…

计算机视觉与模式识别 · 计算机科学 2023-03-16 Lei Zhu , Xinjiang Wang , Zhanghan Ke , Wayne Zhang , Rynson Lau

Multi-Instance Learning (MIL) has shown impressive performance for histopathology whole slide image (WSI) analysis using bags or pseudo-bags. It involves instance sampling, feature representation, and decision-making. However, existing…

计算机视觉与模式识别 · 计算机科学 2024-03-14 Tingting Zheng , Kui Jiang , Hongxun Yao

Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…

计算机视觉与模式识别 · 计算机科学 2024-05-21 Andrew H. Song , Richard J. Chen , Tong Ding , Drew F. K. Williamson , Guillaume Jaume , Faisal Mahmood

Heavy computation is a bottleneck limiting deep-learningbased feature matching algorithms to be applied in many realtime applications. However, existing lightweight networks optimized for Euclidean data cannot address classical feature…

计算机视觉与模式识别 · 计算机科学 2023-03-13 Xiaoyong Lu , Yaping Yan , Bin Kang , Songlin Du

Facial landmark detection, or face alignment, is a fundamental task that has been extensively studied. In this paper, we investigate a new perspective of facial landmark detection and demonstrate it leads to further notable improvement.…

计算机视觉与模式识别 · 计算机科学 2019-08-20 Shengju Qian , Keqiang Sun , Wayne Wu , Chen Qian , Jiaya Jia

Multiple instance learning (MIL) models have achieved remarkable success in analyzing whole slide images (WSIs) for disease classification problems. However, with regard to gigapixel WSI classification problems, current MIL models are often…

计算机视觉与模式识别 · 计算机科学 2023-12-14 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

Deep learning methods are widely applied in digital pathology to address clinical challenges such as prognosis and diagnosis. As one of the most recent applications, deep models have also been used to extract molecular features from whole…

图像与视频处理 · 电气工程与系统科学 2022-03-29 Amir Safarpoor , Jason D. Hipp , H. R. Tizhoosh