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Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

The dynamic environment of laboratories and clinics, with streams of data arriving on a daily basis, requires regular updates of trained machine learning models for consistent performance. Continual learning is supposed to help train models…

机器学习 · 计算机科学 2025-08-12 Zahra Ebrahimi , Raheleh Salehi , Nassir Navab , Carsten Marr , Ario Sadafi

Magnetic resonance imaging (MRI) quality assessment is crucial for clinical decision-making, yet remains challenging due to data scarcity and protocol variability. Traditional approaches face fundamental trade-offs: signal-based methods…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Fankai Jia , Daisong Gan , Zhe Zhang , Zhaochi Wen , Chenchen Dan , Dong Liang , Haifeng Wang

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

计算机视觉与模式识别 · 计算机科学 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

Histomorphology is crucial in cancer diagnosis. However, existing whole slide image (WSI) classification methods struggle to effectively incorporate histomorphology information, limiting their ability to capture key pathological features.…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Baizhi Wang , Rui Yan , Wenxin Ma , Xu Zhang , Yuhao Wang , Xiaolong Li , Yunjie Gu , Zihang Jiang , S. Kevin Zhou

When applying multi-instance learning (MIL) to make predictions for bags of instances, the prediction accuracy of an instance often depends on not only the instance itself but also its context in the corresponding bag. From the viewpoint of…

计算机视觉与模式识别 · 计算机科学 2022-04-25 Tiancheng Lin , Hongteng Xu , Canqian Yang , Yi Xu

A growing number of applications, e.g. video surveillance and medical image analysis, require training recognition systems from large amounts of weakly annotated data while some targeted interactions with a domain expert are allowed to…

计算机视觉与模式识别 · 计算机科学 2022-05-10 Marc-André Carbonneau , Eric Granger , Ghyslain Gagnon

We present a fully-automated segmentation and quantification of the left atrial (LA) fibrosis and scars combining two cardiac MRIs, one is the target late gadolinium-enhanced (LGE) image, and the other is an anatomical MRI from the same…

计算机视觉与模式识别 · 计算机科学 2018-10-23 Fuping Wu , Lei Li , Guang Yang , Tom Wong , Raad Mohiaddin , David Firmin , Jennifer Keegan , Lingchao Xu , Xiahai Zhuang

Fetal abdominal malformations are serious congenital anomalies that require accurate diagnosis to guide pregnancy management and reduce mortality. Although AI has demonstrated significant potential in medical diagnosis, its application to…

计算机视觉与模式识别 · 计算机科学 2025-07-03 Huanwen Liang , Jingxian Xu , Yuanji Zhang , Yuhao Huang , Yuhan Zhang , Xin Yang , Ran Li , Xuedong Deng , Yanjun Liu , Guowei Tao , Yun Wu , Sheng Zhao , Xinru Gao , Dong Ni

Multiple instance learning (MIL) has been increasingly used in the classification of histopathology whole slide images (WSIs). However, MIL approaches for this specific classification problem still face unique challenges, particularly those…

计算机视觉与模式识别 · 计算机科学 2022-03-24 Hongrun Zhang , Yanda Meng , Yitian Zhao , Yihong Qiao , Xiaoyun Yang , Sarah E. Coupland , Yalin Zheng

Objective: We aimed to develop and validate a novel multimodal framework HiMAL (Hierarchical, Multi-task Auxiliary Learning) framework, for predicting cognitive composite functions as auxiliary tasks that estimate the longitudinal risk of…

机器学习 · 计算机科学 2026-02-06 Sayantan Kumar , Sean Yu , Andrew Michelson , Thomas Kannampallil , Philip Payne

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

图像与视频处理 · 电气工程与系统科学 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

Multiple Instance Learning (MIL) has emerged as a promising paradigm for Whole Slide Image (WSI) diagnosis, offering effective learning with limited annotations. However, existing MIL frameworks overlook diagnostic priorities and fail to…

计算机视觉与模式识别 · 计算机科学 2026-03-17 Sungrae Hong , Jiwon Jeong , Jisu Shin , Donghee Han , Sol Lee , Kyungeun Kim , Mun Yong Yi

Left atrial (LA) segmentation from late gadolinium enhanced magnetic resonance imaging (LGE MRI) is a crucial step needed for planning the treatment of atrial fibrillation. However, automatic LA segmentation from LGE MRI is still…

图像与视频处理 · 电气工程与系统科学 2021-07-06 Lei Li , Veronika A. Zimmer , Julia A. Schnabel , Xiahai Zhuang

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Vision-language models (VLMs) have recently been integrated into multiple instance learning (MIL) frameworks to address the challenge of few-shot, weakly supervised classification of whole slide images (WSIs). A key trend involves…

计算机视觉与模式识别 · 计算机科学 2025-12-15 Bryan Wong , Jong Woo Kim , Huazhu Fu , Mun Yong Yi

Long-horizon contact-rich robotic manipulation remains challenging due to partial observability and unstable subtask transitions under contact uncertainty. While hierarchical architectures improve temporal reasoning and bilateral imitation…

机器人学 · 计算机科学 2026-03-27 Thanpimon Buamanee , Masato Kobayashi , Yuki Uranishi

Multimodal Large Language Models (MLLMs) have significantly advanced AI-assisted medical diagnosis, but they often generate factually inconsistent responses that deviate from established medical knowledge. Retrieval-Augmented Generation…

计算机视觉与模式识别 · 计算机科学 2025-07-11 Jinhong Wang , Tajamul Ashraf , Zongyan Han , Jorma Laaksonen , Rao Mohammad Anwer

Objective: Ulcerative colitis (UC), characterized by chronic inflammation with alternating remission-relapse cycles, requires precise histological healing (HH) evaluation to improve clinical outcomes. To overcome the limitations of…

定量方法 · 定量生物学 2025-05-16 Zhengxuan Qiu , Bo Peng , Xiaoying Tang , Jiankun Wang , Qin Guo

Large language models (LLMs) and large multimodal models (LMMs) promise to accelerate biomedical discovery, yet their reliability remains unclear. We introduce ARIEL (AI Research Assistant for Expert-in-the-Loop Learning), an open-source…