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The advancement of single-cell RNA-sequencing (scRNA-seq) technologies allow us to study the individual level cell-type-specific gene expression networks by direct inference of genes' conditional independence structures. scRNA-seq data…

统计方法学 · 统计学 2024-09-20 Changhao Ge , Hongzhe Li

Symbolic regression with polynomial neural networks and polynomial neural ordinary differential equations (ODEs) are two recent and powerful approaches for equation recovery of many science and engineering problems. However, these methods…

机器学习 · 计算机科学 2023-08-28 Colby Fronk , Jaewoong Yun , Prashant Singh , Linda Petzold

We present a novel Bayesian approach for high-dimensional grouped regression under sparsity. We leverage a sparse projection method that uses a sparsity-inducing map to derive an induced posterior on a lower-dimensional parameter space. Our…

统计方法学 · 统计学 2026-05-25 Samhita Pal , Subhashis Ghosal

Reconstruction of gene regulatory networks is the process of identifying gene dependency from gene expression profile through some computation techniques. In our human body, though all cells pose similar genetic material but the activation…

We propose a new framework, called Poisson learning, for graph based semi-supervised learning at very low label rates. Poisson learning is motivated by the need to address the degeneracy of Laplacian semi-supervised learning in this regime.…

机器学习 · 计算机科学 2020-08-17 Jeff Calder , Brendan Cook , Matthew Thorpe , Dejan Slepcev

We propose a new image denoising algorithm when the data is contaminated by a Poisson noise. As in the Non-Local Means filter, the proposed algorithm is based on a weighted linear combination of the bserved image. But in contract to the…

应用统计 · 统计学 2012-01-31 Qiyu Jin , Ion Grama , Quansheng Liu

Architecture, size, and shape of glands are most important patterns used by pathologists for assessment of cancer malignancy in prostate histopathological tissue slides. Varying structures of glands along with cumbersome manual observations…

图像与视频处理 · 电气工程与系统科学 2019-10-10 Malay Singh , Emarene Mationg Kalaw , Wang Jie , Mundher Al-Shabi , Chin Fong Wong , Danilo Medina Giron , Kian-Tai Chong , Maxine Tan , Zeng Zeng , Hwee Kuan Lee

Prostate cancer (PCa) was the most frequently diagnosed cancer among American men in 2023. The histological grading of biopsies is essential for diagnosis, and various deep learning-based solutions have been developed to assist with this…

图像与视频处理 · 电气工程与系统科学 2024-09-16 Ekaterina Redekop , Mara Pleasure , Zichen Wang , Anthony Sisk , Yang Zong , Kimberly Flores , William Speier , Corey W. Arnold

The robust Poisson method is becoming increasingly popular when estimating the association of exposures with a binary outcome. Unlike the logistic regression model, the robust Poisson method yields results that can be interpreted as risk or…

统计方法学 · 统计学 2022-09-14 Denis Talbot , Miceline Mésidor , Yohann Chiu , Marc Simard , Caroline Sirois

Many high-energy physics analyses require the presence of leptons from $W$, $Z$, or $H$ boson decay. For these analyses, signatures that mimic such leptons present a `fake lepton' background that must be estimated. Since the magnitude of…

高能物理 - 实验 · 物理学 2016-06-23 Erich W. Varnes

Correctly assessing the malignancy of breast lesions identified during ultrasound examinations is crucial for effective clinical decision-making. However, the current "golden standard" relies on manual BI-RADS scoring by clinicians, often…

机器学习 · 计算机科学 2024-08-29 Alek Fröhlich , Thiago Ramos , Gustavo Cabello , Isabela Buzatto , Rafael Izbicki , Daniel Tiezzi

Patient-reported outcomes (PROs) directly collected from cancer patients being treated with radiation therapy play a vital role in assisting clinicians in counseling patients regarding likely toxicities. Precise prediction and evaluation of…

机器学习 · 计算机科学 2024-11-19 Yang Yan , Zhong Chen , Cai Xu , Xinglei Shen , Jay Shiao , John Einck , Ronald C Chen , Hao Gao

Neural Processes (NPs; Garnelo et al., 2018a,b) are a rich class of models for meta-learning that map data sets directly to predictive stochastic processes. We provide a rigorous analysis of the standard maximum-likelihood objective used to…

We treat an image restoration problem with a Poisson noise chan- nel using a Bayesian framework. The Poisson randomness might be appeared in observation of low contrast object in the field of imaging. The noise observation is often hard to…

计算机视觉与模式识别 · 计算机科学 2014-12-09 Hayaru Shouno

Positron emission tomography (PET) is an important functional medical imaging technique often used in the evaluation of certain brain disorders, whose reconstruction problem is ill-posed. The vast majority of reconstruction methods in PET…

图像与视频处理 · 电气工程与系统科学 2023-06-09 Tin Vlašić , Tomislav Matulić , Damir Seršić

The PC algorithm uses conditional independence tests for model selection in graphical modeling with acyclic directed graphs. In Gaussian models, tests of conditional independence are typically based on Pearson correlations, and…

统计理论 · 数学 2012-07-03 Naftali Harris , Mathias Drton

The progression of lung cancer implies the intrinsic ordinal relationship of lung nodules at different stages-from benign to unsure then to malignant. This problem can be solved by ordinal regression methods, which is between classification…

计算机视觉与模式识别 · 计算机科学 2021-02-02 Yiming Lei , Hongming Shan , Junping Zhang

Medical images can be used to predict a clinical score coding for the severity of a disease, a pain level or the complexity of a cognitive task. In all these cases, the predicted variable has a natural order. While a standard classifier…

We propose an anomaly detection technique for high-resolution X-ray spectroscopy. The method is based on the neural network architecture variational autoencoder, and requires only {\it normal} samples for training. We implement the network…

天体物理仪器与方法 · 物理学 2019-06-12 Y. Ichinohe , S. Yamada

We introduce a scalable Bayesian preference learning method for identifying convincing arguments in the absence of gold-standard rat- ings or rankings. In contrast to previous work, we avoid the need for separate methods to perform quality…

计算与语言 · 计算机科学 2018-06-08 Edwin Simpson , Iryna Gurevych