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Cellular signaling is essential in information processing and decision making. Therefore, a variety of experimental approaches have been developed to study signaling on bulk and single-cell level. Single-cell measurements of signaling…

定量方法 · 定量生物学 2019-04-18 Carolin Loos , Jan Hasenauer

Brain fiber tracts are widely used in studying brain diseases, which may lead to a better understanding of how disease affects the brain. The segmentation of brain fiber tracts assumed enormous importance in disease analysis. In this paper,…

神经元与认知 · 定量生物学 2020-11-04 Chaoqing Xu , Guodao Sun , Ronghua Liang , Xiufang Xu

Machine learning is a rapidly evolving field with a wide range of applications, including biological signal analysis, where novel algorithms often improve the state-of-the-art. However, robustness to algorithmic variability - measured by…

信号处理 · 电气工程与系统科学 2024-02-16 Tobias Ettling , Sari Saba-Sadiya , Gemma Roig

The segmentation of brain tumors in multimodal MRIs is one of the most challenging tasks in medical image analysis. The recent state of the art algorithms solving this task is based on machine learning approaches and deep learning in…

图像与视频处理 · 电气工程与系统科学 2020-02-11 Dmitrii Lachinov , Elena Shipunova , Vadim Turlapov

Personalized medicine has become an important part of medicine, for instance predicting individual drug responses based on genomic information. However, many current statistical methods are not tailored to this task, because they overlook…

应用统计 · 统计学 2019-10-03 Shih-Ting Huang , Yannick Düren , Kristoffer H. Hellton , Johannes Lederer

As deep learning (DL) efficacy grows, concerns for poor model explainability grow also. Attribution methods address the issue of explainability by quantifying the importance of an input feature for a model prediction. Among various methods,…

机器学习 · 计算机科学 2022-07-01 Daniel Lundstrom , Tianjian Huang , Meisam Razaviyayn

One of the most significant challenges in the field of deep learning and medical image segmentation is to determine an appropriate threshold for classifying each pixel. This threshold is a value above which the model's output is considered…

图像与视频处理 · 电气工程与系统科学 2023-06-28 Ali Fayzi , Mohammad Fayzi , Mostafa Forotan

Cataloging the neuronal cell types that comprise circuitry of individual brain regions is a major goal of modern neuroscience and the BRAIN initiative. Single-cell RNA sequencing can now be used to measure the gene expression profiles of…

Understanding treatment effect heterogeneity has become increasingly important in many fields. In this paper we study distributions and quantiles of individual treatment effects to provide a more comprehensive and robust understanding of…

统计方法学 · 统计学 2026-03-31 Zhe Chen , Xinran Li

Recent advances in brain-vision decoding have driven significant progress, reconstructing with high fidelity perceived visual stimuli from neural activity, e.g., functional magnetic resonance imaging (fMRI), in the human visual cortex. Most…

计算机视觉与模式识别 · 计算机科学 2025-07-04 Le Xu , Qi Zhang , Qixian Zhang , Hongyun Zhang , Duoqian Miao , Cairong Zhao

Brain tumor analysis in MRI images is a significant and challenging issue because misdiagnosis can lead to death. Diagnosis and evaluation of brain tumors in the early stages increase the probability of successful treatment. However, the…

图像与视频处理 · 电气工程与系统科学 2021-12-30 Zahra Sobhaninia , Nader Karimi , Pejman Khadivi , Shadrokh Samavi

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

机器学习 · 计算机科学 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

Recent advancements in artificial intelligence (AI) have precipitated a paradigm shift in medical imaging, particularly revolutionizing the domain of brain imaging. This paper systematically investigates the integration of deep learning --…

图像与视频处理 · 电气工程与系统科学 2024-10-18 Houze Liu , Bo Zhang , Yanlin Xiang , Yuxiang Hu , Aoran Shen , Yang Lin

Medical imaging is a cornerstone of modern healthcare, driving advancements in diagnosis, treatment planning, and patient care. Among its various tasks, segmentation remains one of the most challenging problem due to factors such as data…

计算机视觉与模式识别 · 计算机科学 2025-05-15 Fares Bougourzi , Abdenour Hadid

The spatial topography of functional brain organization is increasingly recognized to play an important role in cognition and disease. Accounting for individual differences in functional topography is also crucial for accurately…

Causal inference has received great attention across different fields from economics, statistics, education, medicine, to machine learning. Within this area, inferring causal effects at individual level in observational studies has become…

统计方法学 · 统计学 2017-02-16 Thai Pham

We explore encoding brain symmetry into a neural network for a brain tumor segmentation task. A healthy human brain is symmetric at a high level of abstraction, and the high-level asymmetric parts are more likely to be tumor regions. Paying…

计算机视觉与模式识别 · 计算机科学 2017-11-20 Hejia Zhang , Xia Zhu , Theodore L. Willke

Neuroscientists and computer vision researchers use model-brain alignment benchmarks to compare artificial and biological vision systems. These benchmarks rank models according to alignment measures such as the similarity of…

神经元与认知 · 定量生物学 2026-04-24 Larissa Höfling , Matthias Tangemann , Lotta Piefke , Susanne Keller , Katrin Franke , Matthias Bethge

The integration of artificial intelligence [AI] into clinical trials has revolutionized the process of drug development and personalized medicine. Among these advancements, deep learning and predictive modelling have emerged as…

机器学习 · 计算机科学 2024-12-11 Sydney Anuyah , Mallika K Singh , Hope Nyavor

Machine learning in medical imaging often faces a fundamental dilemma, namely, the small sample size problem. Many recent studies suggest using multi-domain data pooled from different acquisition sites/centers to improve statistical power.…

计算机视觉与模式识别 · 计算机科学 2024-07-09 Hao Guan , Pew-Thian Yap , Andrea Bozoki , Mingxia Liu
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