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Diffusion models have shown great promise in medical image denoising and reconstruction, but their application to Positron Emission Tomography (PET) imaging remains limited by tracer-specific contrast variability and high computational…

图像与视频处理 · 电气工程与系统科学 2026-02-03 Fumio Hashimoto , Kuang Gong

To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One…

图像与视频处理 · 电气工程与系统科学 2023-08-22 Zeyu Han , Yuhan Wang , Luping Zhou , Peng Wang , Binyu Yan , Jiliu Zhou , Yan Wang , Dinggang Shen

Positron Emission Tomography (PET) is a functional imaging modality that enables the visualization of biochemical and physiological processes across various tissues. Recently, deep learning (DL)-based methods have demonstrated significant…

图像与视频处理 · 电气工程与系统科学 2026-01-16 Yiran Sun , Osama Mawlawi

Positron Emission Tomography (PET) is a vital imaging modality widely used in clinical diagnosis and preclinical research but faces limitations in image resolution and signal-to-noise ratio due to inherent physical degradation factors.…

图像与视频处理 · 电气工程与系统科学 2024-11-11 Boxiao Yu , Kuang Gong

Deep learning has significantly advanced PET image re-construction, achieving remarkable improvements in image quality through direct training on sinogram or image data. Traditional methods often utilize masks for inpainting tasks, but…

计算机视觉与模式识别 · 计算机科学 2025-03-12 Bin Huang , Binzhong He , Yanhan Chen , Zhili Liu , Xinyue Wang , Binxuan Li , Qiegen Liu

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

图像与视频处理 · 电气工程与系统科学 2023-10-12 Wenjun Xia , Yongyi Shi , Chuang Niu , Wenxiang Cong , Ge Wang

Positron Emission Tomography (PET) is an important clinical imaging tool but inevitably introduces radiation hazards to patients and healthcare providers. Reducing the tracer injection dose and eliminating the CT acquisition for attenuation…

计算机视觉与模式识别 · 计算机科学 2024-06-18 Tianqi Chen , Jun Hou , Yinchi Zhou , Huidong Xie , Xiongchao Chen , Qiong Liu , Xueqi Guo , Menghua Xia , James S. Duncan , Chi Liu , Bo Zhou

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

医学物理 · 物理学 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

Low-dose Positron Emission Tomography (PET) imaging presents a significant challenge due to increased noise and reduced image quality, which can compromise its diagnostic accuracy and clinical utility. Denoising diffusion probabilistic…

图像与视频处理 · 电气工程与系统科学 2025-03-03 Boxiao Yu , Savas Ozdemir , Jiong Wu , Yizhou Chen , Ruogu Fang , Kuangyu Shi , Kuang Gong

Ultra-low-dose positron emission tomography (PET) reconstruction holds significant potential for reducing patient radiation exposure and shortening examination times. However, it may also lead to increased noise and reduced imaging detail,…

计算机视觉与模式识别 · 计算机科学 2025-09-03 Mengxiao Geng , Ran Hong , Bingxuan Li , Qiegen Liu

Positron Emission Tomography (PET) and Computed Tomography (CT) are essential for diagnosing, staging, and monitoring various diseases, particularly cancer. Despite their importance, the use of PET/CT systems is limited by the necessity for…

图像与视频处理 · 电气工程与系统科学 2024-10-30 Dac Thai Nguyen , Trung Thanh Nguyen , Huu Tien Nguyen , Thanh Trung Nguyen , Huy Hieu Pham , Thanh Hung Nguyen , Thao Nguyen Truong , Phi Le Nguyen

Deep learning-based reconstruction of positron emission tomography(PET) data has gained increasing attention in recent years. While these methods achieve fast reconstruction,concerns remain regarding quantitative accuracy and the presence…

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

计算机视觉与模式识别 · 计算机科学 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have…

Positron emission tomography (PET) scans expose patients to radiation, which can be mitigated by reducing the dose, albeit at the cost of diminished quality. This makes low-dose (LD) PET recovery an active research area. Previous studies…

图像与视频处理 · 电气工程与系统科学 2026-03-11 Ghulam Nabi Ahmad Hassan Yar , Himashi Peiris , Victoria Mar , Cameron Dennis Pain , Zhaolin Chen

Positron emission tomography (PET) is widely used to assess metabolic activity, but its application is limited by the availability of radiotracers. 18F-labeled fluorodeoxyglucose (18F-FDG) is the most commonly used tracer but shows limited…

图像与视频处理 · 电气工程与系统科学 2025-06-24 Fang Chen , Weifeng Zhang , Xingyu Ai , BingXuan Li , An Li , Qiegen Liu

Positron emission tomography (PET) offers powerful functional imaging but involves radiation exposure. Efforts to reduce this exposure by lowering the radiotracer dose or scan time can degrade image quality. While using magnetic resonance…

计算机视觉与模式识别 · 计算机科学 2026-02-13 Yingkai Zhang , Shuang Chen , Ye Tian , Yunyi Gao , Jianyong Jiang , Ying Fu

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

图像与视频处理 · 电气工程与系统科学 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

医学物理 · 物理学 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

Low-dose PET imaging is crucial for reducing patient radiation exposure but faces challenges like noise interference, reduced contrast, and difficulty in preserving physiological details. Existing methods often neglect both…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Mengxiao Geng , Ran Hong , Xiaoling Xu , Bingxuan Li , Qiegen Liu
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