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Whole Slide Imaging (WSI) has become a gold standard in cancer diagnosis, inspecting multi-scale information from cellular to tissue levels. Processing an entire WSI directly is infeasible due to GPU memory constraints; thus, Multiple…

图像与视频处理 · 电气工程与系统科学 2026-05-08 Tianyi Zhang , Sicheng Chen , Borui Kang , Dankai Liao , Qiaochu Xue , Bochong Zhang , Fei Xia , Zeyu Liu , Yueming Jin

Histopathological image segmentation is a challenging and important topic in medical imaging with tremendous potential impact in clinical practice. State of the art methods rely on hand-crafted annotations which hinder clinical translation…

Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…

图像与视频处理 · 电气工程与系统科学 2024-11-22 Manahil Raza , Ruqayya Awan , Raja Muhammad Saad Bashir , Talha Qaiser , Nasir M. Rajpoot

Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Jayanie Bogahawatte , Sachith Seneviratne , Saman Halgamuge

Melanoma diagnosed and treated in its early stages can increase the survival rate. A projected increase in skin cancer incidents and a dearth of dermatopathologists have emphasized the need for computational pathology (CPATH) systems. CPATH…

图像与视频处理 · 电气工程与系统科学 2023-11-07 Neel Kanwal , Roger Amundsen , Helga Hardardottir , Luca Tomasetti , Erling Sandoy Undersrud , Emiel A. M. Janssen , Kjersti Engan

Whole Slide Images (WSIs) are typically analyzed using multiple instance learning (MIL) methods. However, the scale and heterogeneity of WSIs generate highly redundant and dispersed information, making it difficult to identify and integrate…

计算机视觉与模式识别 · 计算机科学 2025-12-23 Yueting Zhu , Yuehao Song , Shuai Zhang , Wenyu Liu , Xinggang Wang

Multiple Instance Learning (MIL) has been widely applied in pathology towards solving critical problems such as automating cancer diagnosis and grading, predicting patient prognosis, and therapy response. Deploying these models in a…

计算机视觉与模式识别 · 计算机科学 2022-10-18 Syed Ashar Javed , Dinkar Juyal , Harshith Padigela , Amaro Taylor-Weiner , Limin Yu , Aaditya Prakash

Current approaches for classification of whole slide images (WSI) in digital pathology predominantly utilize a two-stage learning pipeline. The first stage identifies areas of interest (e.g. tumor tissue), while the second stage processes…

计算机视觉与模式识别 · 计算机科学 2022-07-20 Marvin Teichmann , Andre Aichert , Hanibal Bohnenberger , Philipp Ströbel , Tobias Heimann

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

图像与视频处理 · 电气工程与系统科学 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

Pathological images play an essential role in cancer prognosis, while survival analysis, which integrates computational techniques, can predict critical clinical events such as patient mortality or disease recurrence from whole-slide images…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Guo Tang , Songhan Jiang , Jinpeng Lu , Linghan Cai , Yongbing Zhang

Multiple instance learning (MIL) is a key algorithm for classification of whole slide images (WSI). Histology WSIs can have billions of pixels, which create enormous computational and annotation challenges. Typically, such images are…

图像与视频处理 · 电气工程与系统科学 2021-11-03 Andriy Myronenko , Ziyue Xu , Dong Yang , Holger Roth , Daguang Xu

Recent advances in whole-slide image (WSI) scanners and computational capabilities have significantly propelled the application of artificial intelligence in histopathology slide analysis. While these strides are promising, current…

计算机视觉与模式识别 · 计算机科学 2023-11-15 Weiyi Wu , Chongyang Gao , Joseph DiPalma , Soroush Vosoughi , Saeed Hassanpour

In the field of computational pathology, the use of decision support systems powered by state-of-the-art deep learning solutions has been hampered by the lack of large labeled datasets. Until recently, studies relied on datasets in the…

计算机视觉与模式识别 · 计算机科学 2018-10-01 Gabriele Campanella , Vitor Werneck Krauss Silva , Thomas J. Fuchs

Lung adenocarcinoma (LUAD) grading depends on accurately identifying growth patterns, which are indicators of prognosis and can influence treatment decisions. Common deep learning approaches to determine the predominant pattern rely on…

计算机视觉与模式识别 · 计算机科学 2026-04-24 Laura Valeria Perez-Herrera , M. J. Garcia-Gonzalez , Karen Lopez-Linares

Whole-slide images (WSIs) from cancer patients contain rich information that can be used for medical diagnosis or to follow treatment progress. To automate their analysis, numerous deep learning methods based on convolutional neural…

计算机视觉与模式识别 · 计算机科学 2026-02-18 Lucas Sancéré , Noémie Moreau , Katarzyna Bozek

Researchers working on computational analysis of Whole Slide Images (WSIs) in histopathology have primarily resorted to patch-based modelling due to large resolution of each WSI. The large resolution makes WSIs infeasible to be fed directly…

计算机视觉与模式识别 · 计算机科学 2021-06-08 Suvidha Tripathi , Satish Kumar Singh , Hwee Kuan Lee

Multiple Instance Learning (MIL) has been widely applied in histopathology to classify Whole Slide Images (WSIs) with slide-level diagnoses. While the ground truth is established by expert pathologists, the slides can be difficult to…

计算机视觉与模式识别 · 计算机科学 2026-03-11 Marie Arrivat , Rémy Peyret , Elsa Angelini , Pietro Gori

Signet ring cell carcinoma (SRCC) of the stomach is a rare type of cancer with a slowly rising incidence. It tends to be more difficult to detect by pathologists mainly due to its cellular morphology and diffuse invasion manner, and it has…

图像与视频处理 · 电气工程与系统科学 2020-11-19 Fahdi Kanavati , Shin Ichihara , Michael Rambeau , Osamu Iizuka , Koji Arihiro , Masayuki Tsuneki

In whole slide images (WSIs) analysis, attention-based multi-instance learning (MIL) models are susceptible to spurious correlations and degrade under domain shift. These methods may assign high attention weights to non-tumor regions, such…

计算机视觉与模式识别 · 计算机科学 2025-12-08 Xin Liu , Weijia Zhang , Wei Tang , Thuc Duy Le , Jiuyong Li , Lin Liu , Min-Ling Zhang

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

图像与视频处理 · 电气工程与系统科学 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai
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