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Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the progressive accumulation of misfolded proteins, leading to cognitive decline. This study presents a novel stochastic modelling approach to simulate the…

神经元与认知 · 定量生物学 2024-11-06 Alec MacIver , Hina Shaheen

Learning interpretable representations of neural dynamics at a population level is a crucial first step to understanding how observed neural activity relates to perception and behavior. Models of neural dynamics often focus on either…

机器学习 · 统计学 2025-01-13 Noga Mudrik , Yenho Chen , Eva Yezerets , Christopher J. Rozell , Adam S. Charles

Recent success in developing increasingly general purpose agents based on sequence models has led to increased focus on the problem of deploying computationally limited agents within the vastly more complex real-world. A key challenge…

机器学习 · 计算机科学 2025-12-23 Geraud Nangue Tasse , Matthew Riemer , Benjamin Rosman , Tim Klinger

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by complex physiological processes. Previous research has predominantly focused on static cerebral interactions, often neglecting the brain's dynamic nature and…

机器学习 · 计算机科学 2024-09-11 Peng Wang , Xin Wen , Ruochen Cao , Chengxin Gao , Yanrong Hao , Rui Cao

We consider the problem of energy-efficient point-to-point transmission of delay-sensitive data (e.g. multimedia data) over a fading channel. Existing research on this topic utilizes either physical-layer centric solutions, namely…

机器学习 · 计算机科学 2017-03-29 Nicholas Mastronarde , Mihaela van der Schaar

When scaling distributed training, the communication overhead is often the bottleneck. In this paper, we propose a novel SGD variant with reduced communication and adaptive learning rates. We prove the convergence of the proposed algorithm…

机器学习 · 计算机科学 2020-12-08 Cong Xie , Oluwasanmi Koyejo , Indranil Gupta , Haibin Lin

Latent space models (LSMs) are often used to analyze dynamic (time-varying) networks that evolve in continuous time. Existing approaches to Bayesian inference for these models rely on Markov chain Monte Carlo algorithms, which cannot handle…

统计方法学 · 统计学 2024-01-19 Joshua Daniel Loyal

Graph neural networks have emerged as a powerful tool for learning spatiotemporal interactions. However, conventional approaches often rely on predefined graphs, which may obscure the precise relationships being modeled. Additionally,…

机器学习 · 计算机科学 2025-02-21 Jeehong Kim , Minchan Kim , Jaeseong Ju , Youngseok Hwang , Wonhee Lee , Hyunwoo Park

Despite the success of deep learning in speech recognition, multi-dialect speech recognition remains a difficult problem. Although dialect-specific acoustic models are known to perform well in general, they are not easy to maintain when…

机器学习 · 计算机科学 2022-05-09 Sanghyun Yoo , Inchul Song , Yoshua Bengio

Complex multivariate time series arise in many fields, ranging from computer vision to robotics or medicine. Often we are interested in the independent underlying factors that give rise to the high-dimensional data we are observing. While…

机器学习 · 统计学 2021-02-11 Simon Bing , Vincent Fortuin , Gunnar Rätsch

Recent advancements in multimodal large language models (MLLMs) have demonstrated remarkable capabilities in processing diverse data types, yet significant disparities persist between human cognitive processes and computational approaches…

计算与语言 · 计算机科学 2025-05-09 Dongxing Yu

Modeling the spatiotemporal nature of the spread of infectious diseases can provide useful intuition in understanding the time-varying aspect of the disease spread and the underlying complex spatial dependency observed in people's mobility…

Gaussian processes offer a flexible kernel method for regression. While Gaussian processes have many useful theoretical properties and have proven practically useful, they suffer from poor scaling in the number of observations. In…

机器学习 · 统计学 2021-08-26 Nick Terry , Youngjun Choe

Cross-modal MRI segmentation is of great value for computer-aided medical diagnosis, enabling flexible data acquisition and model generalization. However, most existing methods have difficulty in handling local variations in domain shift…

计算机视觉与模式识别 · 计算机科学 2023-11-17 Bingnan Li , Zhitong Gao , Xuming He

This paper presents novel information-theoretic PHY layer performance improvement for combating the system fading effects in wireless terrestrial communication applications. Robust space-time system strategies in cooperation with the high…

信号处理 · 电气工程与系统科学 2019-10-31 Ardavan Rahimian

Speech emotion recognition is crucial to human-computer interaction. The temporal regions that represent different emotions scatter in different parts of the speech locally. Moreover, the temporal scales of important information may vary…

声音 · 计算机科学 2023-03-06 Shuaiqi Chen , Xiaofen Xing , Weibin Zhang , Weidong Chen , Xiangmin Xu

Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease…

计算机视觉与模式识别 · 计算机科学 2025-11-27 Xin Honga , Jie Lin , Minghui Wang

Functional connectivity analysis is an important tool for characterizing interactions among brain regions, particularly in studies of neurodegenerative disorders such as Alzheimer's disease (AD). Gaussian graphical models (GGMs) provide a…

统计方法学 · 统计学 2026-04-14 Panpan Zhang , Shiying Xiao , W. Hudson Robb , Dandan Liu , Angela L. Jefferson , Jun Yan

Understanding the interactions between biomarkers among brain regions during neurodegenerative disease is essential for unravelling the mechanisms underlying disease progression. For example, pathophysiological models of Alzheimer's Disease…

Latent dynamics discovery is challenging in extracting complex dynamics from high-dimensional noisy neural data. Many dimensionality reduction methods have been widely adopted to extract low-dimensional, smooth and time-evolving latent…

机器学习 · 计算机科学 2019-07-02 Qi She , Anqi Wu