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Existing image generation models face critical challenges regarding the trade-off between computation and fidelity. Specifically, models relying on a pretrained Variational Autoencoder (VAE) suffer from information loss, limited detail, and…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Chenrui Ma , Xi Xiao , Tianyang Wang , Xiao Wang , Yanning Shen

Different types of staining highlight different structures in organs, thereby assisting in diagnosis. However, due to the impossibility of repeated staining, we cannot obtain different types of stained slides of the same tissue area.…

图像与视频处理 · 电气工程与系统科学 2024-04-17 Zexin Li , Yiyang Lin , Zijie Fang , Shuyan Li , Xiu Li

We propose a novel hematoxylin and eosin (H&E) stain normalization method based on a modified U-Net neural network architecture. Unlike previous deep-learning methods that were often based on generative adversarial networks (GANs), we take…

图像与视频处理 · 电气工程与系统科学 2022-11-11 Chi-Chen Lee , Po-Tsun Paul Kuo , Chi-Han Peng

Generative artificial intelligence (AI) is rapidly transforming medical imaging by enabling capabilities such as data synthesis, image enhancement, modality translation, and spatiotemporal modeling. This review presents a comprehensive and…

图像与视频处理 · 电气工程与系统科学 2025-08-14 Xuanru Zhou , Cheng Li , Shuqiang Wang , Ye Li , Tao Tan , Hairong Zheng , Shanshan Wang

Understanding the way cells communicate, co-locate, and interrelate is essential to furthering our understanding of how the body functions. H&E is widely available, however, cell subtyping often requires expert knowledge and the use of…

Histopathological diagnoses of tumors in tissue biopsy after Hematoxylin and Eosin (H&E) staining is the gold standard for oncology care. H&E staining is slow and uses dyes, reagents and precious tissue samples that cannot be reused.…

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

计算机视觉与模式识别 · 计算机科学 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

计算机视觉与模式识别 · 计算机科学 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…

Given an incomplete image without additional constraint, image inpainting natively allows for multiple solutions as long as they appear plausible. Recently, multiplesolution inpainting methods have been proposed and shown the potential of…

计算机视觉与模式识别 · 计算机科学 2021-03-19 Jialun Peng , Dong Liu , Songcen Xu , Houqiang Li

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

Purpose: In digital histopathology, virtual multi-staining is important for diagnosis and biomarker research. Additionally, it provides accurate ground-truth for various deep-learning tasks. Virtual multi-staining can be obtained using…

图像与视频处理 · 电气工程与系统科学 2023-12-15 Johannes Lotz , Nick Weiss , Jeroen van der Laak , Stefan Heldmann

We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…

计算机视觉与模式识别 · 计算机科学 2023-09-08 Alexandre Tiard , Alex Wong , David Joon Ho , Yangchao Wu , Eliram Nof , Alvin C. Goh , Stefano Soatto , Saad Nadeem

Generative Artificial Intelligence (AI) holds immense potential in medical applications. Numerous studies have explored the efficacy of various generative AI models within healthcare contexts, but there is a lack of a comprehensive and…

人机交互 · 计算机科学 2023-12-19 Jinghong Chen , Lingxuan Zhu , Weiming Mou , Zaoqu Liu , Quan Cheng , Anqi Lin , Jian Zhang , Peng Luo

Digital pathology has advanced significantly over the last decade, with Whole Slide Images (WSIs) encompassing vast amounts of data essential for accurate disease diagnosis. High-resolution WSIs are essential for precise diagnosis but…

图像与视频处理 · 电气工程与系统科学 2024-08-28 Xuan Xu , Saarthak Kapse , Prateek Prasanna

A scalable and robust 3D tissue transcriptomics profile can enable a holistic understanding of tissue organization and provide deeper insights into human biology and disease. Most predictive algorithms that infer ST directly from histology…

Highway construction workers face a high risk of serious injury or death. Image-based training materials depicting hazardous scenarios are essential for engaging safety instruction but remain scarce due to ethical and logistical barriers.…

计算机视觉与模式识别 · 计算机科学 2026-05-13 Trevor Neece , Mason Smetana , Lev Khazanovich

Hard coatings play a critical role in industry, with ceramic materials offering outstanding hardness and thermal stability for applications that demand superior mechanical performance. However, deploying artificial intelligence (AI) for…

计算机视觉与模式识别 · 计算机科学 2026-03-30 Binwei Chen , Huachao Leng , Chi Yeung Mang , Tsz Wai Cheung , Yanhua Chen , Wai Keung Anthony Loh , Chi Ho Wong , Chak Yin Tang

Histological Tertiary Lymphoid Structures (TLSs) are increasingly recognized for their correlation with the efficacy of immunotherapy in various solid tumors. Traditionally, the identification and characterization of TLSs rely on…

图像与视频处理 · 电气工程与系统科学 2024-08-27 Qiuli Wang , Yongxu Liu , Li Ma , Xianqi Wang , Wei Chen , Xiaohong Yao

Over the past years, deep generative models have achieved a new level of performance. Generated data has become difficult, if not impossible, to be distinguished from real data. While there are plenty of use cases that benefit from this…

密码学与安全 · 计算机科学 2022-03-21 Ning Yu , Vladislav Skripniuk , Dingfan Chen , Larry Davis , Mario Fritz