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相关论文: Cochlear Wave Propagation and Dynamics in the Huma…

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We develop an analytic model of the mammalian cochlea. We use a mixed physical-phenomenological approach by utilizing existing work on the physics of classical box-representations of the cochlea, and behavior of recent data-derived…

组织与器官 · 定量生物学 2021-08-20 Samiya A Alkhairy , Christopher A Shera

The human cochlea is a remarkable device, able to discern extremely small amplitude sound pressure waves, and discriminate between very close frequencies. Simulation of the cochlea is computationally challenging due to its complex geometry,…

数值分析 · 数学 2025-10-20 Edward Givelberg , Julian Bunn

In this work, we investigate the phenomenon of transverse resonance and transverse standing waves that occur within the cochlea of living organisms. It is demonstrated that the predisposing factor for their occurrence is the cochlear shape,…

神经元与认知 · 定量生物学 2023-10-10 M. V. Semotiuk , A. V. Palagin

Most sounds of interest consist of complex, time-dependent admixtures of tones of diverse frequencies and variable amplitudes. To detect and process these signals, the ear employs a highly nonlinear, adaptive, real-time spectral analyzer:…

神经元与认知 · 定量生物学 2014-08-12 T. Reichenbach , A. J. Hudspeth

We investigate instabilities in a stochastic mathematical model of cochlear dynamics. The cochlea is modeled as a spatio-temporal dynamical system made up of a spatially distributed array of coupled oscillators, together with the cochlear…

生物物理 · 物理学 2018-09-10 Maurice Filo , Bassam Bamieh

Cochlea displays complex and highly nonlinear behavior in response to wide-ranging auditory stimuli. While there have been many recent advancements in the modeling of cochlear dynamics, it remains unclear what mathematical structures…

生物物理 · 物理学 2018-08-07 Keith Hayton , Dimitrios Moirogiannis , Marcelo Magnasco

Cochlea is an important auditory organ in the inner ear. In most mammals, it is coiled as a spiral. Whether this specific shape influences hearing is still an open problem. By employing a three dimensional fluid model of the cochlea with an…

生物物理 · 物理学 2008-02-12 Yong Zhang , Chul Koo Kim , Kong-Ju-Bock Lee , Youngah Park

The cochlea or inner ear has a remarkable ability to amplify sound signals. This is understood to derive at least in part from some active process that magnifies vibrations of the basilar membrane (BM) and the cochlear partition in which it…

生物物理 · 物理学 2015-07-08 William Ko , John M. Stockie

This study experimentally validates a numerical model of electromagnetic propagation through the human head during the pronunciation of different vowels, with the goal of improving our understanding of the underlying physical phenomena. A…

We describe a numerical method to simulate an elastic shell immersed in a viscous incompressible fluid. The method is developed as an extension of the immersed boundary method using shell equations based on the Kirchhoff-Love and the planar…

数值分析 · 数学 2025-10-20 E. Givelberg

We use a combination of analytical theory, numerical simulation, and data analysis to study the propagation of acoustic waves along coronal loops. We show that the intensity perturbation of a wave depends on a number of factors, including…

天体物理学 · 物理学 2009-11-10 J. A. Klimchuk , S. E. M. Tanner , I. De Moortel

The cochlea's capacity to process a broad range of sound intensities has been linked to nonlinear amplification by critical oscillators. However, while the increasing sensitivity of a critical oscillator upon decreasing the stimulus…

生物物理 · 物理学 2025-12-16 Henri Ver Hulst , Carles Blanch Mercader , Frank Jülicher , Pascal Martin

The tuning curve of the cochlea measures how large an input is required to elicit a given output level as a function of the frequency. It is a fundamental object of auditory theory, for it summarizes how to infer what a sound was on the…

生物物理 · 物理学 2013-05-29 Marcelo O. Magnasco

Instrumental variables are commonly used to estimate effects of a treatment afflicted by unmeasured confounding, and in practice instruments are often continuous (e.g., measures of distance, or treatment preference). However, available…

统计方法学 · 统计学 2018-07-05 Edward H. Kennedy , Scott A. Lorch , Dylan S. Small

Sound produces surface waves along the cochlea's basilar membrane. To achieve the ear's astonishing frequency resolution and sensitivity to faint sounds, dissipation in the cochlea must be canceled via active processes in hair cells,…

Elastic wave propagation provides a noninvasive way to probe granular materials. The discrete element method using particle configuration as input, allows a micromechanical interpretation on the acoustic response of a given granular system.…

地球物理 · 物理学 2018-08-28 Hongyang Cheng , Stefan Luding , Kuniyasu Saitoh , Vanessa Magnanimo

Cough is a protective reflex conveying information on the state of the respiratory system. Cough assessment has been limited so far to subjective measurement tools or uncomfortable (i.e., non-wearable) cough monitors. This limits the…

音频与语音处理 · 电气工程与系统科学 2024-12-04 Jesús Monge-Alvarez , Carlos Hoyos-Barceló , Luis M. San-José-Revuelta , Pablo Casaseca-de-la-Higuera

Forces transmitted by bones are routinely studied in human biomechanics, but it is challenging to measure them non-invasively, especially outside of laboratory settings. We introduce a technique for non-invasive, in vivo measurement of…

定量方法 · 定量生物学 2026-05-04 Ali Yawar , Daniel H. Aslan , Daniel E. Lieberman

The extraordinary sensitivity of the mammalian inner ear has captivated scientists for decades, largely due to the crucial role played by the outer hair cells (OHCs) and their unique electromotile properties. Typically arranged in three…

生物物理 · 物理学 2023-11-16 Alessandro Altoè , Christopher A Shera

Because the cochlear is very small and complex, vibration data of the whole basement membrane are not yet available from existing experiments, To address this question, this work technically adopts the mathematical and biological methods to…

生物物理 · 物理学 2021-01-12 W. Yao , J. Ma , J. Liang , X. Huang
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